Thrush is a serious disease that affects the mucous membranes, skin, and even internal organs.
"Diflucan" refers to a group of antifungal medications and is used to eliminate mycoses of various etiologies.
Candidiasis is caused by yeast-like fungi, the disease develops when the immune system weakens, and the pathogenic microflora that is constantly present on the skin and mucous regions, activating, begins to spread uncontrollably.
Structure
The drug is produced in the following dosage forms:
- capsules;
- solution for injection;
- powder for suspension.
According to patients, different forms of release allow everyone to choose a convenient method of taking the drug.
Capsules contain fifty or one hundred and fifty milligrams of an active microelement - fluconazole, tablets are labeled on the shell and are packaged in cell packages of seven pieces.
The powder for the manufacture of the suspension is dispensed with a volume of five milliliters; there is a measuring spoon in the package. One milliliter of the finished product contains ten milligrams of fluconazole. The powder is milky in color, has no aroma and impurities.
The solution is dispensed in transparent, glass bottles of fifty, one hundred and two hundred milliliters. In one milliliter of the solution there are two milligrams of the active trace element (fluconazole).
The properties
"Diflucan" belongs to the group of antifungal drugs and has tremendous therapeutic efficacy in relation to most forms of mycoses. The drug eliminates yeast-like fungi, as well as dermatophytes.
Penetrating into the body, the active component of the drug - fluconazole - is quickly absorbed through the mucous membranes of the digestive system into the general bloodstream, the maximum content of the main substance in the blood is observed already after an hour and a half after the use or administration of Diflucan. The result is stored for thirty hours, which makes it possible to use the medicine only once every twenty-four hours.
Fluconazole immediately enters all biological fluids, which makes Diflucan even more effective.
Indications
The drug "Diflucan" is recommended for patients to eliminate and prevent the following diseases and conditions:
- Vaginal candidiasis (diseases of the mucous membranes, skin, internal organs caused by yeast-like fungi).
- Pityriasis versicolor (superficial non-inflammatory recurrent disease of the skin of fungal origin).
- Onychomycosis (nail disease caused by a fungal infection).
- Sporotrichosis (chronic fungal infection of the skin).
- Candidiasis of the oral mucosa.
- Balanitis (inflammatory process of the glans penis).
- Balanoposthitis (a common inflammatory process on the surface of the skin of the penis).
- Candiduria (persistent elevated fungal content is detected in the urine).
- Candidemia (a disease in which Candida fungi enter the bloodstream, along with the bloodstream, they penetrate into different organs and tissues).
- Mycosis of the nails (fungal infection, which is most often manifested on human skin).
Diflucan in various forms is also prescribed for prophylactic patients for cancer with chemotherapy or radiation exposure.
Contraindications
The drug is prescribed by the doctor after examining the patient. Before treatment, the patient must thoroughly read the instructions for use, since the medicine has certain prohibitions on the use of:
- Individual intolerance to substances in the composition of the drug.
- Lactose intolerance.
- Age to three years.
With extreme caution, medication is prescribed to patients if they have the following ailments:
- Diseases of the liver and kidneys.
- Fluconazole allergy.
- Cardiovascular diseases.
Instructions for use
The daily dosage of the drug and the duration of therapy in most situations is determined by the doctor in a strictly individual order for each patient. It depends on the diagnosis, weight, age.
According to the instructions, the drug is prescribed once to eliminate recurrent vaginal candidiasis. For the treatment of other forms of fungal infections, Diflucan is prescribed once a day, but continues to be taken until the clinical symptoms of the disease are eliminated.
For persons with weak immunity or with the human immunodeficiency virus, the duration of therapy is two months, after which it is necessary to switch to maintenance treatment in an individual dosage.
The elimination of yeast-like fungi in plasma and urine should occur over an extended period in a daily dosage of four hundred milligrams. After improving the general condition of the patient and eliminating the clinical symptoms of candidiasis, they switch to the maintenance dosage of the drug - two hundred milligrams.
The elimination of candidiasis of the oral mucosa, pharynx of the esophagus is carried out in a daily dose of from fifty to one hundred milligrams for fourteen days. For children, the dosage of the medicine is set by the attending doctor purely individually, depending on the age and weight of the patient.
For preventive purposes and in the treatment of fungal infections in the oral cavity while wearing dentures, a person is recommended to take Diflucan in a daily dosage of fifty milligrams together with oral local antiseptic agents for two weeks.
When eliminating balanitis and balanoposthitis, which are caused by fungal strains, representatives of a strong half of humanity are recommended to take one hundred and fifty milligrams of the drug once.
In case of fungal infection or dermatomycosis, adults are prescribed Diflucan (in any form) in a daily dosage of one hundred and fifty milligrams also for fourteen days. If necessary, treatment can be extended for another thirty days under the supervision of a therapist.
The destruction of pityriasis versicolor with fluconazole is carried out in a dosage of three hundred milligrams once every seven days for one month.
In rare situations, the solution and suspension can be used in pediatric practice for babies under three years of age. In this case, the dosage is determined strictly by the doctor, based on weight, in addition, the medicine is not used every day, but once every three days.
Can I use Diflucan during pregnancy?
In medicine, there is no information regarding the effect of an active trace element on the fetus during pregnancy. According to the information, a woman’s prolonged use of fluconazole-based medications in large doses in a “large position” can provoke pathologies in development, in particular, the occurrence of skull disorders, deformation of the hips and ribs.
When taking Diflucan in a dose of not more than one hundred and fifty milligrams a day, such violations on the part of the fetus were not observed, but the use of the drug for the treatment of women “in an interesting position” is possible only if the expected benefit for the mother will be much greater than the risks for the baby.
In addition, with the appearance of thrush in a pregnant woman, the doctor tries to find similar medicines that can not harm the future mother and baby.
Since the active substance can easily pass into breast milk, it is not recommended to use Diflucan during lactation. If treatment is necessary, a woman needs to find a substitute drug or interrupt lactation.
Adverse reactions
Doctors warn, and patients note in the reviews that during the treatment with "Diflucan" there is a risk of developing the following negative phenomena:
- Dizziness.
- Paresthesia (a disorder of sensitivity, which is characterized by spontaneously developing sensations of burning, tingling, crawling ants).
- Migraine (a neurological disease, the most common and characteristic symptom of which is episodic or regular severe and painful headache in one half of the head).
- Trouble sleeping.
- Irritability.
- Pain in the epigastric zone.
- Upset stool.
- Nausea and vomiting.
- Excessive thirst.
- Failures in the liver.
- Increased activity of hepatic transaminases.
- Rashes on the skin.
- Anaphylaxis (an allergy of an immediate type, a state of sharply increased body sensitivity, which develops when the allergen reappears).
- Angioneurotic edema (acute disease, which is characterized by the instant development of local edema of the mucous cavity, subcutaneous tissue and the skin itself).
In most cases, Diflucan is remarkably tolerated by patients, and adverse reactions are extremely rare.
Interaction with other medicines
With the joint use of the drug with anticoagulants, the likelihood of bleeding increases.
According to reviews and instructions for use with Diflucan and analogues, while using Diflucan with Hydrochlorothiazide, there is an increase in the content of the active trace element in the blood by about forty percent, which must be taken into account in this drug ratio.
With the joint interaction of the drug with Diazepam and its substitutes, psychomotor reactions in the patient may fail. This pharmacological interaction requires a reduction in the dosage of fluconazole and control of the patient's health.
When taking the medicine with "Rifampicin" together, you need to increase the dosage of "Diflucan", because under the influence of the second fluconazole it is immediately released from the body and does not have time to exert a therapeutic effect.
Features
According to reviews and instructions for the use of "Diflucan", prolonged use in large doses increases the risk of liver intoxication, therefore, during treatment it is necessary to constantly monitor the level of hepatic transaminases, and if they increase, take such patients under close supervision.
People of retirement age in the absence of impaired renal function do not need to adjust the daily dosage.
Analogues of Diflucan
According to reviews of tablets, it is known that the following drugs are generic of the drug:
- Difluzole.
- Flucostat.
- Futsis.
- "Flucorus".
- Fluconorm.
- Wagisept.
- Mikomaks.
- "Fluconazole".
- Fluconazole
According to the instructions and reviews about "Diflucan", before changing the drug to another drug, it is important to consult a doctor to make sure there are no contraindications.
Storage
Diflucan capsules are dispensed from pharmacies without a prescription, but the solution and powder for the preparation of suspensions can only be purchased if it is available.
The medication must be kept in a place inaccessible to children, excluding the penetration of sunlight. The expiration date is indicated on the package; upon its expiration, the drug should be discarded.
It is recommended to keep the prepared suspension in the refrigerator for no more than fourteen days. Before each use, the medicine should be shaken. The average price of Diflucan in pharmacies is 300-2000 rubles, depending on the form of release.
Opinions
Women leave the most reviews about Diflucan, as the problem of thrush affects almost every representative of the fair half of humanity.
Candidiasis can be triggered after taking strong antibacterial drugs, hormonal medications, and a decrease in the body's protective functions.
With variable steps, periods of exacerbation are replaced by the resumption of the disease, acquiring a chronic form. In such situations, capsules at a dose of one hundred and fifty milligrams help remarkably.
According to reviews of Diflucan, with thrush it is an effective medicine for Candida fungi. In the preparation, the manufacturer combined all the most useful trace elements. The drug has almost no contraindications. But it is forbidden to people with heart, kidney and liver diseases.