How does the Venter drug work? Reviews about this medicine will be presented at the very end of the article. We will also tell you about what indications and contraindications this medication has, whether it has adverse reactions, how to take it correctly, etc.
Form, packaging, composition
What is included in the preparation "Venter"? Reviews of specialists say that the active component of this medication is sucralfate. It also contains additional constituents in the form of corn starch, colloidal silicon dioxide, talc and magnesium stearate.
Currently available for purchase:
- Venter tablets. Patient reviews indicate that this form of medicine goes on sale in contour blisters that are placed in packs of cardboard.
- Granules. The drug is packaged in 2 g sachets. 50 sachets can be contained in one cardboard pack.
Pharmacological characteristics
What are the properties of the medicine “Venter”? Reviews of doctors inform us that this agent includes such an active substance as sucralfate. This component is a disaccharide, which consists of sucrose sulfate and aluminum hydroxide.
After taking the drug inside, a fairly rapid healing of ulcers (peptic) is noted. It should also be noted that the drug in question prevents the development of peptic ulcer of the duodenum and stomach, protect their mucous membranes from the effects of hydrochloric acid and pepsin.
Why do many doctors prescribe the Venter drug to their patients? Reviews of experienced specialists suggest that this medication can significantly reduce the activity of pepsin (by about 30%), without having a significant effect on the acidity of the gastric juice.
The principle of action of the drug in question is based on the binding of its active substance to the proteins of the affected mucous tissues. Thus, the medicine “Venter” forms a protective film on the surface of the ulcer. Such an effect accelerates its scarring, regeneration of injuries, and also prevents the formation of stress ulcers and the development of relapses of peptic ulcer. In addition, phosphate absorption in the digestive tract is reduced.
Pharmacokinetics of the drug
Is the medicine “Venter” absorbed? Instructions, reviews of experienced doctors say that after taking the drug inside, its insignificant absorption into the systemic circulation occurs.
In the human body, the drug does not form clinically significant concentrations and does not exhibit a systemic effect.
It should also be noted that the medication in question is not metabolized. A small part of it is excreted through the kidneys, and the rest through the intestines (unchanged).
The drug "Venter": indications for use
Reviews of experts say that this medication should be prescribed only by the attending physician and only according to indications. The drug "Venter" is very effective in the following cases:
- as a prevention of exacerbations of peptic ulcer of the duodenum and stomach;
- as a prophylaxis of stress ulcers;
- with reflux esophagitis;
- with hyperphosphatemia in people with uremia on hemodialysis.
Contraindications to the use of granules and tablets
The medicine "Venter" is forbidden to take in the presence of the following conditions:
- high sensitivity to the elements of the drug;
- severe violations in the work of the kidneys;
- in childhood (up to four years).
It should also be said that with extreme caution, the “Venter” medication is prescribed for people with chronic renal failure, as well as during pregnancy and breastfeeding.
The drug "Venter": instructions for use
Reviews of experts indicate that the medicine "Venter" in the form of granules and tablets should be taken only inside.
The tablets are not chewed. They are swallowed in their entirety and washed down with the required amount of water. If it is impossible to use the whole drug, it is pre-dissolved in pure water, which is subsequently drunk. They do exactly the same with the drug in the form of granules.
The prepared solution must be drunk 30-60 minutes before a meal. The duration of therapy should be established only by a narrow specialist (gastroenterologist), taking into account the individual characteristics of the patient and the results of a medical examination.
The daily dosage for adults is 2 sachets or 2 tablets. One must be taken before dinner, and the second in the evening, before bedtime.
If the patient is diagnosed with hyperphosphatemia, then the indicated dose is reduced.
In the presence of a peptic ulcer, it is allowed to take an increased daily dosage of the drug (2 times). The duration of treatment for people with this diagnosis is 12 weeks. The disappearance of signs of the disease should not cause drug withdrawal. Therapy is continued until a diagnostic examination confirms scarring of the ulcers.
Take the drug for adult patients to prevent stress ulcers should be one sachet or tablet 6 times a day. In order to prevent the recurrence of peptic ulcer, an adult is prescribed one tablet or sachet twice a day.
The drug “Venter” for reflux, reviews of which are ambiguous, is also prescribed twice a day.
The maximum daily dosage of the drug is 8 sachets or tablets. With impaired renal function, the therapeutic course is reduced.
Children from four years old should be given ½-1 tablet of the drug no more than 4 times a day. Using the drug in the form of granules in childhood is not recommended.
Overdose cases
The medication in question is well tolerated by patients. In this regard, the risk of signs of overdose is reduced to zero. However, in some cases, increased doses of this medication may exacerbate allergic reactions and intolerance reactions. Thus, the patient may develop the following symptoms: vomiting, rashes and irritation on the skin, abdominal pain, nausea. These cases require symptomatic treatment.
If a person is diagnosed with kidney failure, then with prolonged therapy, he may develop aluminum intoxication, which turns into osteomalacia or encephalopathy. This requires immediate drug withdrawal, hemodialysis, peritoneal dialysis, hemofiltration and deferoxamine.
Adverse reactions
What adverse reactions occur during treatment with Venter? Side effects (reviews of this medicine will be presented below) are found in almost all medicines. And the drug in question is no exception. After taking it, the patient may develop headaches, constipation, dry mouth, nausea, insomnia, flatulence, dizziness, vomiting, lower back pain, diarrhea, allergic reactions, drowsiness, gastralgia, etc.
Drug interaction
With simultaneous treatment with antacids, it is necessary to observe the interval between medications for at least half an hour.
Combination therapy can lower the absorption of Ofloxacin, Cimetidine, tetracyclines, Ranitidine, Ciprofloxacin, indirect anticoagulants, Digoxin, Norfloxacin and Theophylline. The interval between taking these drugs and Venter should be more than 2 hours.
The combination of the medication in question and Phenytoin reduces the absorption and normal concentration of the latter, which can cause the seizure to resume. The interval between doses of these funds should be 2 hours.
Analogues of the drug
What can replace the Venter drug? Analogs (reviews of which are mostly positive) of this tool are sold in all pharmacies. These include drugs such as Alsucral, Sucralfat, Ankrusal, Ulgastran and Sucrat.
It should also be noted that the following drugs have a similar effect: De-Nol, Maalox, Renny and Almagel.
Reviews about the drug
Disorders of the digestive tract disturb many people. Therefore, reviews about the drug "Venter" are quite common. Patients using this medication report that it affects different people in different ways. Some argue that the drug in question does not always help get rid of problems in the digestive tract. Others report that if you take the medicine in combination (for example, with Omez, Fosfalugel, Rennie and others), then it helps to heal ulcers and erosion quite effectively.
It should also be noted that a large number of patients are pleased with the price of the drug. In tablets, it can be purchased for only 230-250 rubles.