The drug "Hexamethylenetetramine" or in another way "Urotropin" describes the instruction as a tool belonging to the group of prodrugs. The use of this combined medication has a pronounced hypotensive and antiseptic effect. It should be especially noted that in the acidic environment of the body, the “Urotropin” agent, the instruction to which this confirms, breaks down with the release of a special formaldehyde that has an antimicrobial effect during urination. For this reason, special drugs should be taken at the same time as this medicine. They should be made on the basis of components that can slightly acidify urine.
This combination preparation is currently being produced in the form of tablets and a 40% solution for injection. As an active ingredient, the listed forms include methenamine.
Urotropin tablets are recommended for use by the user mainly for the purpose of eliminating various infectious diseases of the urinary tract. For example, cystitis or pyelitis. The drug is administered intravenously for influenza, encephalitis, sepsis, meningitis, arachnoiditis and
typhoid fever. With this application, the drug “Urotropin” (instructions indicate this), due to the acid reaction directly occurring in the focus of inflammation, exhibits a pronounced antiseptic and “colloidoclastic” effect. In addition, with the intravenous administration of the drug, certain shifts occur in the ionic composition of the plasma, which, in turn, activates the body's defenses. It is this reaction that experts explain the positive effect of this drug in all kinds of neurasthenic conditions and arteriosclerotic disorders. Among other things, the use of Urotropin tablets is recommended for the treatment of gout, since, when combined, uric acid and formaldehyde form
formaldehyde-uric acid. However, in this case, the drug should be taken on an empty stomach so that it does not break down in the stomach. Use of this medicine is also recommended for a variety of allergic skin diseases (including polymorphic erythema and urticaria), cholangitis - inflammation of the bile ducts, cholecystitis - inflammation of the gallbladder and eye diseases (iridocyclitis and keratitis).
The main contraindications to the appointment of this drug are individual intolerance to methenamine and the presence of hepatic-renal failure. With great caution, you should take these tablets in case of dehydration.
As for possible adverse reactions, various dyspeptic phenomena should be highlighted here first of all. For example, diarrhea, nausea, vomiting, and abdominal pain. Hematuria, albuminemia and crystalluria may also occur as a result of taking the drug "Urotropin". Patient reviews also note the risk of developing urticaria, skin rash, soreness and redness directly at the injection site.