In the article, we consider the instructions and reviews for the medication "Cetrin".
The drug is a popular antiallergic drug. This medicine effectively eliminates negative allergic symptoms due to the active substance cetirizine. The principle of action of this component is that it stops the work of histamine receptors. Allergic histamine is unable to bind to receptors.
Reviews about Cetrin and its effectiveness are abundant on the Internet.
Description of the medication
The drug is an antihistamine designed to eliminate the symptoms of allergic reactions in children and adult patients. “Cetrin” refers to the category of selective and selective antihistamines, also called histamine blockers. This drug has an unusually strong sedative effect along with inhibition of the nervous system. Due to this, it is used mainly in the role of anti-allergic medication, starting from the age of six.
This is confirmed by the instructions for the use of tablets "Cetrin." According to reviews, the drug is as good for adults as it is for children.
Release format and composition
The release form of this medication is round tablets, which have a white tint. They are covered with a protective membrane that dissolves when it enters the intestines. These tablets are convex on both sides, on one of them there is a risk. Tablets are packed in blisters of ten pieces, which are placed in turn in cardboard boxes of two or three plates.
Each pill includes 10 milligrams of the active substance, which is cetirizine hydrochloride. The composition of this drug also includes auxiliary components: lactose, povidone, stearic acid and starch.
This is stated in the instructions for use of tablets "Cetrin". We will review reviews about the medication below.
Pharmacokinetics of the drug
The therapeutic effect of Cetrin is due to the action of the active component of cetirizine on the body. Thanks to the action of this medication, the development of allergic reactions in the cells of the human body is blocked, which leads to a decrease in the manifestation of external symptoms of allergies.
Immediately after ingestion, the cetirizine component can be rapidly absorbed from the digestive system. Eating does not affect this in any way and does not affect the quality of absorption. In adults, immediately after taking this medicine in standard dosage, its maximum concentration is reached after an hour and amounts to 290 nanograms per milliliter.
The binding of the drug to plasma proteins reaches 93%. During the use of this drug in the amount of 10 milligrams for ten days, cumulation of cetirizine is not observed. In a small amount, the drug presented is metabolized in the body by dealkylation to form an inactive metabolite.
Indications for use
The medical tool "Cetrin" is intended for stopping and preventing various allergic reactions, for example:
- With the inflammatory process of the nasal mucosa, which is caused by flowering plants.
- Against the background of urticaria, including idiopathic.
- With angioedema.
- Against the background of an allergy to ultraviolet radiation.
- With hay fever.
- Against the background of allergic conjunctivitis.
- With bronchial asthma.
- With the appearance of skin itching.
- Against the background of increased lacrimation.
- Against the background of allergic reactions caused by bites of mosquitoes, bees and various insects.
In addition, this drug is prescribed to patients during periods of taking other medications or food products that cause unwanted allergic manifestations.
Instructions for use of the medication
Pills should be taken orally, washed down with some water. Eating does not affect the digestibility of the drug presented. The instructions recommend that you take this drug one pill once a day. This is best done in the evening.
Children who are over six years of age are prescribed the following scheme: the drug should be taken twice a day for 5 milligrams (this is exactly half the tablet). The instructions strictly prohibit the use of this medicine for persons under the age of six.
How many days should Tsetrin take?
The duration of use of Cetrin directly depends on a number of factors. The determining ones are the severity and nature of the course of an allergic disease. So, "Cetrin" in order to relieve acute allergic reactions is used for ten to fourteen days. In the event that allergy symptoms disappear faster (in less than ten days), then the medication is stopped earlier. Thus, in the treatment of acute allergic reactions, the duration of administration is determined by the rate of disappearance of symptoms.
As soon as the signs of allergic reactions disappear, you can immediately stop taking the drug. True, in this case, the continuous use of Cetrin should not be allowed to last longer than fourteen days. When using “Cetrin” as a prophylactic for stopping an exacerbation of an allergic disease (for example, runny nose, hay fever, dermatitis, and so on), a longer course of therapy is required. Feedback on the use of Cetrin is mostly positive.
As a rule, the preventive course of using the drug is from one to one and a half months. Doctors are advised to take Cetrin as part of prophylaxis during the entire time the potential allergen remains in the environment. For example, if a person has an allergy to flowering plants, it is required to take Cetrin in May or June until absolutely all the trees have faded.
The drug can be used for the treatment of bronchial asthma as a basic antihistamine in combination with other medicines. In this case, Cetrin is taken in a course lasting from fifteen to twenty days. Next is a break of one week. After that, the medication resumes. A similar method of taking "Tsetrin" in the treatment of bronchial asthma has been practiced for years.
Children at an early age (up to seven years) who are prone to allergic reactions like dermatitis can use Cetrin for prophylactic purposes from three to four times a year, in short courses of ten to fourteen days. Such prophylaxis is required to prevent atopic march in babies who are prone to allergic reactions.
And the instructions and reviews about the tablets "Cetrin" confirm that adverse reactions are extremely rare.
Contraindications to the use of the medication
This medical product has a number of different contraindications. Before starting use, you should always consult your doctor. It is also recommended to follow the rules that are prescribed by the instructions attached to the drug. This medicine is not recommended for use by the following persons:
- People who suffer from severe kidney and liver disease.
- Children under the age of six.
- Patients who have hypersensitivity to the ingredients of the drug.
- Pregnant women.
- Patients who have malabsorption syndrome or suffer from lactose intolerance.
- Women who are breastfeeding.
The minimum dosage of this drug (subject to medical supervision) can be prescribed even if there is a violation of the heart rhythm, and in addition, against the background of epilepsy and other diseases of the nervous system. It is allowed to take this medicine from the age of sixty-five years.
Side effects
According to reviews of Cetrin, against the background of its intake, a dry mouth may appear along with increased drowsiness. The following negative effects may occur much less frequently:
- Dizziness or headache.
- The occurrence of an upset or discomfort in the digestive system.
- The development of migraine and allergic reactions.
- Onset of nausea or vomiting.
- The appearance of psychomotor agitation.
Instructions for use and reviews of "Cetrin" confirm this.
special instructions
Due to the possible occurrence of seizures, people who suffer from epilepsy should take Cetrin with great care. The instructions recommend that adults refrain from taking alcoholic beverages during treatment with this drug.
People with trauma to the spinal cord, as well as prostatic hyperplasia, should use this medication with great caution because of the risk of urinary retention. This drug may also cause a drowsiness. This must be taken into account when driving a car or when working with dangerous machinery.
About this warns the instructions for use of "Cetrin." Reviews and analogues of this drug are also of interest to many, as will be discussed below.
Drug overdose
In this case, gastric lavage is necessary. It is worth noting that there is no special antidote to this medicine. The simultaneous administration of a dosage five times higher than the norm can cause the following symptoms in a person:
- The appearance of an upset digestive system.
- Dilation of the pupils along with confusion.
- The occurrence of fatigue and heart palpitations.
- The occurrence of drowsiness, agitation, and irritability.
- Urinary retention or constipation.
Storage conditions
This medicine should be stored in a place that is inaccessible to children. In this case, the storage temperature should not be more than twenty- five degrees. The expiration date from the moment of production of the drug is usually twenty-four months. Upon completion of this tool is strictly forbidden to take. This drug is released over-the-counter.
According to reviews, analogues of Cetrin are no less effective in combating allergies.
Analogues of the drug
This medicine has several widely known analogues, consider them:
- The drug "Zodak". The active ingredient in this drug is cetirizine. This analogue is produced in the form of a syrup, and in addition, in the form of tablets with a 10-milligram dosage and in drops. Testimonials from patients indicate that there is no significant difference between Cetrin and Zodak.
- The drug "Tavegil." The active substance in this case is clemastine. It is worth noting that the antiallergic effectiveness of Tavegil in time lasts half as much as that of Tsetrin.
- The drug "Claritin." The active ingredient in this drug is loratadine. This medication does not cause a sedative effect, it almost does not interact with other medicines.
Reviews about "Cetrin"
The medicine “Cetrin” is currently a widely known and popular anti-allergic medicine. On the Web, people greatly praise this medication for its effectiveness.
They like that as part of the treatment, it is enough to use only one tablet per day to achieve the desired effect. The advantages of Tsetrin are noted, such as antipruritic effect and the absence of a sedative effect when taking pills. Patients praise this medicine for its low price, and in addition, for efficiency, since the drug is enough for a whole month with constant use.
What other reviews are there about Cetrin tablets?
The disadvantages include the fact that this drug is quite bitter and poorly soluble in water. Another disadvantage is the age limit: children under 6 years of age should not take this medicine. This drug is also not recommended during pregnancy.
Some also report that Tsetrin is far from always coping with its antiallergic task. Patients also complain of side effects that, when using the drug, can manifest themselves in the form of dizziness and psychomotor agitation.
Thus, the reviews about "Cetrin" on the Web are very different: some customers praise him, while others, on the contrary, believe that the medication is of average effectiveness. But it is worth emphasizing that in most reviews these tablets are still given a positive assessment.
So, we reviewed the instructions and reviews for the medication “Cetrin”.