Faced with joint pain, people try to find effective anti-inflammatory drugs. This is exactly what Metindol is. Instructions for use position it as a non-steroidal anti-inflammatory drug. What is its use and is there any harm from the medicine? How does it affect the body? And why does the choice of doctors and patients stop on this drug?
a brief description of
The drug belongs to non-steroidal anti-inflammatory drugs. Its active ingredient is the non-hormonal agent indomethacin. “Metindol”, thanks to it, inhibits the activity and production of substances (prostaglandins, cyclooxygenases), which stimulate the development of the inflammatory process in the body, cause pain, and increase temperature.
Basically, the medicine is intended for the treatment of pathologies of the musculoskeletal system. It is important to understand that such a tool does not eliminate the causes of pathology. It is able to alleviate the general condition of the patient, thereby improving the quality of life of the patient.
According to the instructions for use attached to the medicine "Metindol", this agent has an excellent antipyretic effect. In the form of ointment and gel, the drug is used to eliminate swelling of the joints, pain, erythema, morning stiffness, joint swelling. The use of this medication allows the patient to significantly expand the range of motion.
Dosage Forms
Manufacturers today delight with a wide variety of manufactured types of the drug. Today, pharmacists have provided the following drug groups of Metindol:
- tablets;
- capsules;
- dragee;
- solutions;
- suppositories;
- gel;
- ointment.
Indications for use
As previously noted, the drug “Metindol” is mainly recommended for eliminating the symptoms of pathologies of the musculoskeletal system of an inflammatory and degenerative nature. Instructions for use provide an extensive list of diseases in which the remedy is effective. Among them:
- Personage-Turner disease;
- juvenile chronic arthritis;
- Paget's disease;
- arthritis provoked by Reiter's disease;
- rheumatism;
- psoriatic arthritis;
- Ankylosing spondylitis ;
- rheumatoid arthritis;
- gouty arthritis (exception - acute attacks of gout).
The medicine perfectly relieves pain. Therefore, the drug is effective in the following pathologies:
- toothache;
- lumbago;
- traumatic injuries;
- headache;
- surgical interventions;
- tendonitis;
- neuralgia;
- bursitis;
- myalgia;
- sciatica.
The tool is intended for symptomatic therapy of pericarditis, Bartter’s syndrome, helps with adnexitis, algodismenorea, inflammation localized in the pelvis. This drug is widely used as a painkiller tocolytic at the time of delivery.
The drug “Metindol” is in demand, the instructions for use fully confirm this, and with various infectious and inflammatory ailments of the ENT organs, which are accompanied by severe pain (pharyngitis, tonsillitis, otitis media).
In addition, the medication is prescribed for febrile syndrome (lymphomas, hepatic metastases, lymphogranulomatosis).
"Metindol" - ointment or gel - is used for traumatic injuries of the ligamentous apparatus, tendons, joints, muscles. These are various sprains, bruises, dislocations, excessive loads. Especially in demand is an agent in the form of an ointment with the following pathologies:
- tendonitis;
- bursitis;
- tenosynovitis;
- myalgia;
- lumbago;
- radiculitis;
- sciatica;
- deforming osteoarthrosis;
- rheumatoid arthritis;
- osteochondrosis;
- humeroscapular periarthritis;
- ankylosing spondylitis;
- psoriatic arthritis.
The only exception is the pathology of the small hip and intervertebral joints.
Tablet dosage
Depending on the form of release, the drug can be prescribed orally, rectally or externally, as well as intravenously, intramuscularly.
Let's consider how to use the Metindol tablets. The instruction recommends adhering to the following rules:
At the initial stage of the disease, adults are prescribed 25 mg about 2-3 times a day. This product should be taken after a meal. A greater effect can be achieved by washing it with milk.
If it is not possible to achieve effectiveness with such an amount of the drug, then the daily dose is increased to 150 mg. This refers to three times 50 mg each.
How to use Metindol Retard? Instructions for use advises - 1-2 times a day for 1 pill. After all, one tablet of such a medicine contains 75 mg of the active substance. The maximum daily dose is 200 mg. Once the desired effect is achieved, the dose should be gradually reduced over 4 weeks.
Solution use
For relief of acute pain or chronic exacerbations, Metindol tablets may be recommended. But the most effective solution is for intramuscular administration. In this case, an injection of 60 mg of the drug is done 1-2 times a day. Such treatment can last one to two weeks. After that, the doctor recommends switching to rectal medications or tablet forms of the drug are prescribed.
Rectal dosage
Suppositories are recommended to be administered 1-3 times a day, 50 mg each. Before using such a remedy, the intestines should be completely empty and the candle should be inserted as deep as possible. In case of gout attacks, up to 200 mg of the drug in suppositories per day can be prescribed.
Ointments and gels
They are intended for outdoor use only. They are applied to the affected joints about 3-4 times during the day. Applying occlusive dressings is not recommended. For adults, the total amount of ointment per day should not exceed 15 cm (the length of a strip of product squeezed out of the tube). For children, the norm is 7.5 cm.
Contraindications
Like any other medicine, it is only necessary to use the drug “Metindol retard” only as prescribed by the doctor. Instructions for use provide a list of contraindications. Not prescribed for:
- heart defects;
- peptic ulcer disease;
- bleeding (intracranial or from the digestive tract);
- “Aspirin” triad;
- ulcerative colitis;
- cirrhosis with portal hypertension;
- violation of color and visual perception;
- puffiness;
- hypertension
- chronic heart failure;
- bronchial asthma;
- liver failure;
- pathology of the optic nerve ;
- bleeding disorders (hemophilia, frequent bleeding);
- pregnancy
- impaired blood formation (leukopenia, anemia);
- pathologies of the vestibular apparatus;
- breastfeeding;
- decreased auditory perception.
A rectal preparation is contraindicated in case of hemorrhoids, proctitis, rectal bleeding.
Ointment, gel are not used for children under one year of age, as well as with impaired integrity of the skin.
Extremely carefully prescribed drug "Metindol" for elderly people, children, as well as for the following pathologies:
- depression;
- epilepsy;
- parkinsonism;
- hyperbilirubinemia;
- thrombocytopenia.
Side effects
Despite the fact that the drug "Metindol" receives reviews mostly positive, it should be used with extreme caution. Some patients may experience side effects:
- Digestive system. Sometimes there is vomiting, heartburn, nausea. There may be a decrease in appetite, hyperbilirubinemia.
- The sensory organs. The patient may experience tinnitus, a change in taste perception. Some people have clouding of the cornea, hearing loss, conjunctivitis, visual impairment, diplopia.
- Nervous system. The drug can lead to peripheral neuropathy, depression, fatigue, increased drowsiness, dizziness, irritability. In some cases, there is agitation, insomnia, headache.
- The cardiovascular system. The patient may feel tachyarrhythmia, high blood pressure. Some patients have swelling, and heart failure worsens.
- Urinary system. The instruction provides the following possible complications: nephrotic syndrome, hematuria, malfunction of the renal system, papillary necrosis, interstitial nephritis.
- Hematopoietic organs. The drug can contribute to the development of anemia, provoke bleeding (gastrointestinal, uterine, hemorrhoidal).
- Allergic manifestations. As a result of taking the medicine, urticaria, erythema nodosum, skin rash, itching, and anaphylactic shock sometimes occur .
Drug overdose
The following signs indicate an overestimated dose of the drug:
- dizziness;
- nausea;
- headache;
- vomiting
Sometimes patients experience cramps. This is a dangerous and very serious condition.
The first thing to do is to remove the remnants of the drug from the body. In the future, symptomatic therapy is undertaken. It is aimed at stopping unpleasant signs of an overdose.
special instructions
Do not self-medicate and do not take any medications, including Metindol Retard, without consulting a doctor. The instruction warns that elderly people, patients with diseases of the kidneys, liver and gastrointestinal tract, hypertension, heart failure, epilepsy, parkinsonism should use this medicine with extreme caution.
All patients who are prescribed the drug "Metindol", it is recommended to systematically monitor the function of the kidneys, liver, observe the change in the picture of peripheral blood.
It is undesirable to use the above remedy simultaneously with other NSAIDs. Categorically it is not recommended to combine the drugs "Metindol" and "Diflunizal". The drug reduces the effect on the body of diuretics. The severity of nephrotoxic effects leads to the combined use of drugs "Metindol" and "Paracetamol." Glucocorticosteroids, drugs "Corticotropin", "Ethanol", "Colchicine" provoke a risk of gastrointestinal bleeding.
As mentioned above, do not apply the product in the form of ointment, gel on damaged skin. In addition, carefully avoid getting the drug on the mucous membranes or in the eyes.
Throughout treatment, one should refrain from activities that require a fast reaction rate, attention span.
Consumer opinion
Most patients are satisfied with Metindol Retard. Their reviews indicate the effectiveness of the drug. People notice that the tool almost always helps everyone to relieve pain discomfort provoked by a variety of disorders of the musculoskeletal system, which are inflammatory in nature. Patients indicate that even a very strong sensation, this tool can eliminate. But in this case, as a rule, you need to take 2 tablets.
Some people experience unpleasant manifestations of Metindol Retard. Reviews of such people indicate side effects. As a rule, headache is noted.
Conclusion
Everyone should realize that the use of NSAIDs can never be considered safe. No matter how effective the remedy, it is worth taking it with some caution. Without fail, the doctor who will prescribe this drug for you will take care of monitoring the state of the body during therapy. The patient himself must also carefully monitor his feelings. If you feel the occurrence of any side effects, then the drug “Metindol” is not quite right for you. In this case, consult a doctor. He will recommend you another, no less effective means to combat unpleasant pathologies.