Today in pharmacies you can’t find Chlorhexidine ointment, but there are multicomponent medicinal formulations containing this antiseptic. The substance has long established itself as a reliable tool for topical application. Under the name "Chlorhexidine" candles and solutions are available. Consider the features of this antiseptic substance, then turn to the trade names of creams and ointments containing it.
general information
Chlorhexidine is an antiseptic. According to the molecule, it is 1,6-di- (para-chlorophenylguanido) -hexane. For medicinal purposes, a bigluconate substance is used. This is a dichloride-containing product of the transformation of biguanide. Structurally maximally similar to bigumal. An antiseptic is active relatively negative, positive in a study of a gram of bacteria. It is used in the fight against treponema, chlamydia, ureaplasma, bacteroids, neisseria, gardnerella. The drug against tuberculous mycoplasma is ineffective. Helps with infection with simple and herpetic viruses. Does not affect spores, viruses.
Stability is observed after antiseptic treatment of the skin. Due to this, chlorhexidine-containing ointments are used to cleanse the epidermis, and the solutions have found widespread use in surgical practice. The substance is able to persist on the skin in an amount that provides a bactericidal effect. Activity is observed in the presence of suppuration, blood, although the parameters decrease.
The nuances of pharmacology
Chlorhexidine, which is part of some ointments, is widely used in various fields of medicine. This substance (mainly in liquid form) is treated by the doctor’s hands, surgical field, and instrumentation. Chlorhexidine can be used in case of septic, purulent processes. They wash the wounds, body cavities. The tool is used to prevent sexually transmitted diseases. Advantageously, a 0.5% chlorhexidine solution is used for such purposes. In surgical practice, the required surfaces are treated with liquid twice, keeping a couple of minutes between events. To quickly sterilize the instrumentation, it is immersed in the medicinal composition for five minutes. An agent with a concentration of 0.5%, alcohol-based, is suitable for hand disinfection. It is also used to work with burns, wounds. To disinfect hands, you can use a twice as saturated aqueous solution of chlorhexidine.
Dosage Forms
Abroad, chlorhexidine is used for the manufacture of "Distearyl". In this product, the antiseptic in question is contained in a concentration of 1.5% in the form of a bigluconate. Another 15% is reserved for benzalkonium. The composition has a coloring component. Benzalkonium increases the disinfection effect. Thanks to the dye, you can immediately see which zones are processed. The tool has found use in surgical practice for processing the surgical field. They disinfect the equipment used in the clinics.
Sibicort ointment with chlorhexidine is in demand. The antiseptic in question is contained in an amount of 1%, the same amount is reserved for hydrocortisone. This is an anti-inflammatory, antibacterial drug that treats eczema, dermatitis, and bacteria infection.
Chlorhexidine - an integral element of a number of toothpastes, means for rinsing the oral cavity. The substance is used for the manufacture of dental gels used for applying applications to mucous membranes.
Ointments: names
There is no Chlorhexidine ointment on the domestic market, but there are several medicinal products that contain the antiseptic in question. These include the Sibicort mentioned above. In addition, chlorhexidine is included in the means for dental use:
- "Dentamet."
- Dicloran Dent.
Chlorhexidine is one of the elements of the Bepanten Plus drug. He is included in the Pantoderm Plus remedy. Chlorhexidine is present in medicines:
- Bemilon.
- "D-Panthenol Plus Antiseptic."
More information on popular products: Sibikort
Such an ointment based on chlorhexidine contains in one gram of the product 10 mg of antiseptic and the same amount of hydrocortisone. The drug is available in tubes with the presence of 20-100 g of the drug. The product belongs to the class of antibacterial, anti-inflammatory and anti-itch drugs. It is prescribed if chronic eczema is bothering, dermatitis has been identified, aggravated by bacterial infection. You can not use this ointment with hypersensitivity to active components or excipients. The product is not used if there are foci on the skin due to syphilis and tuberculosis. A contraindication to use is a viral infection.
As noted in the instructions for use of the cream with chlorhexidine Sibikort, this drug can cause an allergic response to the body. Possible increased susceptibility to light radiation. Hydrocortisone, included in the product, can provoke skin atrophy, the appearance of acne, thinning of the integument, and erythema. There are cases when the integument burned in the area of ​​application, they became dry and irritated. Redness of the skin, itching, swelling are possible.
With prolonged use, application over large areas, impervious materials may manifest systemic negative effects. These include purpura, acne, hypercorticism, telangiectasia. With prolonged use, there is a risk of secondary infection of skin lesions. There is a possibility of hypertrichosis. Chlorhexidine, which is part of Sibikort, can cause dryness, dermatitis. In the first few minutes after application, the integument may be sticky. When using the drug in the fight against gingivitis, the following are possible: deterioration in the ability to perceive taste, the appearance of tartar, discoloration of the teeth.
Bepanten Plus
Cream with chlorhexidine is intended for external use. The product is made in the form of a matte uniform white product. A yellowish tint is allowed. There is a specific weak aroma. The substance should be uniform, soft. One gram contains 50 mg of dexpanthenol and ten times less chlorhexidine in the form of hydrochloride. Paraffin, macrogol, water, lanolin, alcohols, pantolactone are used as additional ingredients. The medication is packaged in tubes with a capacity of 3.5-100 g. The product belongs to the class of antimicrobials that activate regenerative processes and inhibit inflammation of drugs. Thanks to the antiseptic, the cream is effective against bacteria typical of the skin integument - there are almost always such ones on the body, they penetrate into the damaged areas, especially when contaminated. The second main component, in turn, is soon transformed into pantothenic acid. This substance is significant for the formation and regeneration of cells.
As you can learn from the instructions for the cream with chlorhexidine "Bepanten Plus", the medicine relieves pain, because it cools the treated area. It protects the integument from infection and stimulates regeneration. It is easily applied, distributed, removed from the skin. The tool does not have oily, sticky. There is currently no information on kinetics.
Technical information
Recommended use of ointment with chlorhexidine “Bepanten Plus” for infection of superficial skin lesions, for the treatment of nipple cracks when breastfeeding. Indications are chronic focal processes (pressure sores, difficult healing ulcers) and wounds caused by surgical intervention. Bepanten Plus is used in case of small lesions for which there is a high risk of infection.
The drug is distributed in a thin layer once or several times a day over the surfaces in need. First you need to clean the skin. An open method of treatment and the use of dressings are allowed. Using the drug can provoke the appearance of urticaria, itching areas.
According to the instructions for the ointment with chlorhexidine "Bepanten Plus", the drug is prohibited if the affected area is located in the auricle, and also in the case when the wound is very dirty, deep. You can not use the tool if a high sensitivity to any component of the product is detected. During breastfeeding, pregnancy, cream is used carefully, without treating large areas. During use, you need to protect your eyes from the penetration of drugs into them. It is strictly forbidden to take the ointment inside.
Nuances and rules
A bite, a stab wound, a very contaminated wound, a large area, depth - all this requires specialized medical intervention and is not treated with Bepanten Plus cream. Keep in mind the risk of tetanus. If the use of a cream with chlorhexidine does not reduce the size of the damage, the wound does not heal in one and a half to two weeks, you need to see a doctor. To this extent, severe reddening of the edges, swelling of the zone, pain, and fever are forced. Similar manifestations indicate a risk of sepsis.
There is no evidence of an overdose. Bepanten Plus is not used simultaneously with other antiseptics, as there is a possibility of negative mutual influence.
D-Panthenol
On sale there is a fairly popular ointment with chlorhexidine - "D-Panthenol." The instruction for the use of this drug states that the product is made in the form of a cream, white or close to this shade, having a uniform structure. The drug is packaged in tubes of 25-50 g. One hundred grams of product contains five dexpanthenol and 0.776 g of chlorhexidine in the form of a bigluconate 20% solution. Alcohols, macrogol, water, pantolactone, lano, petroleum jelly, dimethicone, propylene glycol are used as additional ingredients.
Officially, the drug is referred to as stimulants of regenerative processes, belongs to the group of drugs that improve trophism, tissue repair. The ointment is intended for external use. The product belongs to the class of combined preparations, fights against microbes, inhibits the activity of inflammatory foci, locally improves regeneration.
“D-Panthenol” is a cream with chlorhexidine, which is transformed into pantothenic acid in the skin cells due to the presence of the active substance. An antiseptic shows an effect against vegetative species of bacteria, positive and negative, in a Gram study. The tool is effective against yeast and lipophilic viruses, eliminates dermatophytes. For bacterial spores, an antiseptic is only dangerous when the temperature rises. Using the product allows you to clean the covers, disinfect them with a minimal risk of irritation. If you apply the cream on the wound surface, this will protect it from infection and accelerate regeneration.
It is possible and impossible
Like the identical preparation "Panthenol plus Chlorhexidine", the cream "D-Panthenol" is intended for the treatment of small wound surfaces, if there is a risk of infection. These are minor burns and scratches, damage due to scratching of the skin, minor cuts, abrasions. The drug is used for superficial infectious foci on skin lesions. It is used to treat nipples that become covered with cracks during lactation. You can use the drug in a chronic wound process. This is observed if there are pressure sores, the product helps with trophic ulcers. It is used to treat wounds after surgery.
As you can learn from the instructions of the ointment with chlorhexidine "D-Panthenol", the drug is designed for external application from one to several times daily. Before using the pharmaceutical product, the surface of the wound is cleaned. You can apply the product to inflamed areas. Open treatment and the use of dressings are allowed. Using the product can cause itching, hives. Do not use the medication for the auricle, with severe contamination, severe injury, deep damage, high susceptibility to the components of the composition used by the manufacturer.
Pantoderm Plus
Pantoderm Plus ointment containing dexpanthenol and chlorhexidine is popular among patients. The drug is made in the form of a creamy mass for local external application. The product is white or as close to this color as possible. The concentration of the active ingredient is 5%. Packed in 30 g tubes. 100 g of the preparation contains 5 g of dexpanthenol and chlorhexidine bigluconate in an amount of 0.076 g. The manufacturer used additional ingredients as water, paraffin, alcohols, propylene glycol, pantolactone, macrogol, dimethicone, squalane.
The medication belongs to the class of combined. Designed for external therapy. The instructions for the use of ointment with chlorhexidine "Pantoderm Plus" indicate: the antimicrobial effect of the drug, the ability to inhibit inflammatory processes, activate regenerative. The medication is intended to treat a small wound process, the course of which is accompanied by the danger of infection. It is used in the presence of bacteria in superficial skin lesions. They treat the nipples of nursing mothers if they are bothered by cracks. Ointment is used after surgery and for chronic wounds. The tool is intended for application to the skin from once a day or more. Pre-areas are cleaned. You can use the ointment yourself or apply under a bandage. Application can provoke an allergy.
Bemilon
The instructions for use of ointment with chlorhexidine "Bemilon" noted that the product is intended for external use. One gram of product contains 1 mg of betamethasone and five times more chlorhexidine. The drug is packaged in tubes of 15-30 g.
The drug fights bacteria, inflammatory processes. This is a combined medication, both antimicrobial and GCS. Betamethasone is a steroid that has a local effect. The tool is effective against allergies, inflammation, edema, proliferation, itching. It has a pronounced vasoconstrictor effect, more significant than that of other fluorine derivatives of corticosteroids. The systemic effect is minimal, since only a small amount is absorbed through the skin. When applied to the integument, neutrophil accumulation is prevented, exudation, cytokine generation is weakened. The drug inhibits the transportation of macrophages. As a result, granulation, infiltration weaken.
Thanks to chlorhexidine, the ointment fights against germs, eliminating both positive and Gram negative species. The tool is effective against dermatophytes, yeast.
Technical data
Bemilon is prescribed for the treatment of psoriasis, necrobiosis, dermatitis, neurodermatitis, eczema. It is used for various forms of erythema, for the treatment of lymphocytoma, lymphoplasia. The drug is indicated for some types of lupus, with lichen planus, itchy skin due to various reasons. It is prescribed for phlebotoderma.
The drug is intended for external application from two to three times a day. The product is distributed in a thin layer over diseased skin, rubbed lightly on the surface. If the course is mild, a single use daily is sufficient. If the case is difficult to treat, occlusive dressings can be used. This option is not suitable for children. At a minor age with facial lesions, ointment is used for no more than five days in a row.
The nuances of using
Application can provoke acne, striae, itching, burning, dryness of the integument, follicles, prickly heat, hypertrichosis. Prolonged use is accompanied by a risk of atrophic processes, local hirsutism, purpura, and pigmentation reduction. There is a risk of telangiectasia. Too long treatment courses can cause systemic phenomena that are usually caused by steroid drugs.
You can not use the drug for syphilis, tuberculosis, viral invasion of the skin. Contraindications are skin tumors, trophic ulceration caused by varicose veins, rosacea, acne and skin reactions after receiving the vaccine. "Bemilon" is not used to treat skin rashes in children under one year of age, if such is due to diaper rash. You can not use the drug with increased susceptibility of the composition.
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The ability to absorb active elements during local application of a dental gel is close to zero. Accordingly, there are no kinetic parameters for the drug in question.
"Metrogil Dent" is prescribed for the treatment of infection, foci of inflammation in the oral mucosa, periodontal. The drug is used for different variants of the course of gingivitis, periodontitis. It is indicated for cheilitis, Vincent's gingivitis, weighted with ulcers and tissue necrosis. "Metrogil Denta" helps with a combination of periodontal disease and gingivitis, effective in stomatitis with aphthae. It is used if wearing prostheses provoked inflammatory foci, is prescribed for periodontal abscess, periodontitis, alveolitis.
The pharmaceutical product is not recommended for minors. It is not used for pathologies of the central nervous system, PNS. You can not prescribe a remedy for blood diseases, including those previously recorded, as well as with increased susceptibility to active and auxiliary components, nitroimidazole transformation products.
About application experience
As people who used Chlorhexidine in the form of a solution or ointments with this component note, the product effectively disinfects integuments and objects. The substance reliably treats inflammatory foci. Very rarely, people notice the occurrence of allergies. The drug is safe, as those who use it admit, but it is very cheap, therefore it is available to almost everyone.