"Cinnarizine": indications for use, analogues, reviews

In the article, we consider the indications for the use of honey. the drug "Cinnarizine".

The drug is a calcium channel blocker with a significant effect on the vessels located in the brain. The medication is used in the complex treatment of various pathologies of the central nervous system.

The composition and dosage form of the drug

Indications for the use of "Cinnarizine" will be presented below. It is made in the form of tablets for oral administration, which have a rounded shape, white color and a biconvex surface. The main active ingredient of this medication is the substance of the same name cinnarizine, the content of which in one tablet is 25 mg. In addition, the composition of the medicine includes some additional compounds:

• wheat starch;
• colloidal silicon dioxide;
• lactose;
• magnesium stearate;
• povidone K25.

The drug is packaged in blisters, 50 tablets each. A cardboard pack contains one blister, as well as instructions for using the medication.

Pharmacological properties

What do the indications for use depend on?

Cinnarizine, which is the main active element of this medical product, is able to block the calcium channels of cell membranes, as a result of which the influx of calcium ions is suppressed. A consequence of this effect is a decrease in the tone (relaxation) of smooth muscle cells of arterial vessels, which are localized mainly in the structures of the central nervous system. In addition, the result of such pharmacological effects of the tablets “Cinnarizine” have several therapeutic properties, which include:

• Strengthening the processes of blood flow into the cells of the brain and the nutrition of neurocytes, which are cells of the nervous system.
• Reducing the severity of circulatory failure in brain tissue, such as dizziness, tinnitus, systematic headaches.
• Strengthening the stability of the structures of the nervous system to conditions of oxygen starvation (hypoxia).
• Increasing the elasticity of red blood cells with the normalization of their passage through the vessels of the microvasculature.
• Lowering blood viscosity with the normalization of its rheological properties (liquefaction).
• Reducing the severity of reactions of arteries in the brain to vasoconstrictive active compounds produced in the body (norepinephrine, bradykinin, adrenaline).

Indications for use in the instructions for "Cinnarizine" are described in detail.

While taking this drug, its main active ingredient is quite quickly and almost completely absorbed into the general bloodstream and enters the central nervous system through the blood-brain barrier. This component undergoes a metabolic process in the liver with the formation of inactive decay products, excreted from the body mainly with feces and to a small extent with urine. The half-life of the drug (half-dosage withdrawal period) is about five hours.

Indications for use of "Cinnarizine"

The tool is used in the complex therapy of various brain pathologies that can develop against the background of circulatory disorders, with a deterioration in blood flow in the peripheral tissues.

The indications for the use of the drug “Cinnarizine” include:

• Dementia, which is a decrease in the level of intelligence that often develops in elderly people against the background of insufficient blood supply in the structures of the brain.
• A history of ischemic stroke (the death of a piece of tissue in the brain), which is the result of a pronounced and sharp deterioration in blood circulation. Reviews about the drug "Cinnarizine" and indications for use will be given at the end of the article.
• Dyscirculatory encephalopathy, which is a pathological condition that develops with a systematic deterioration of blood circulation in the tissues of the central nervous system.
• A variety of vestibular disorders, which are accompanied by dizziness, noise in the head, vomiting and nausea of ​​central origin.
• Recovery period after traumatic brain injury. What other indications for the use of the drug “Cinnarizine” exist?
• The recovery period after hemorrhagic stroke (a consequence of hemorrhages in the brain tissue).
• Also, indications for the use of the drug “Cinnarizine” are pathological disorders in the peripheral circulation - obliterating arteritis, intermittent claudication, Raynaud's disease, trophic changes in tissues, and diabetic angiopathy.

In addition, this medication can be used to prevent motion sickness ("air" or "sea" disease).

Indications for the use of "Cinnarizine" should be strictly observed.

Contraindications

Categorical medical contraindications for the use of a pharmacological agent are increased susceptibility to any of the elements of the drug, the period of breastfeeding, pregnancy.

With some caution, the drug is used in concomitant cases of Parkinson's disease.

Before using this medication, the appointment of a specialist should eliminate the presence of contraindications.

Dosage

The medicine "Cinnarizine" is intended for oral use, it is advisable to take it after a meal. It is undesirable to chew a tablet and drink it with a large volume of liquid. Dosages and regimen of this medication directly depend on clinical indications:

• with deterioration of peripheral circulation, 50-75 mg of the drug is prescribed 3 times a day;
• with circulatory disorders in the central nervous system - 25-75 mg 3 times a day;
• with a variety of vestibular disorders - 25 mg 3 times a day;
• in the prevention of "air" and "sea" disease - for adults, the drug is prescribed in a dosage of 25 mg half an hour before the trip, for children 1/2 tablet, if necessary, the medication can be repeated, but this should be done no earlier than six hours later .

In cases of development of hypersensitivity to the Cinnarizine drug in patients, the initial dose should be ½ tablets, after which it must be gradually increased to obtain the expected therapeutic result. The duration of the therapeutic course with this medication varies from several weeks to three to six months and is determined individually by the specialist in each case.

Adverse reactions

Against the background of the use of Cinnarizine in the form of tablets, some negative side effects may occur from the following systems and organs:

1. Digestive system - dry mouth, dyspepsia (instability of stool, bloating), abdominal pain, jaundice, which is caused by stagnation of bile in the hepatobiliary system.
2. Nervous system - drowsiness, increased fatigue, headaches, increased tone of skeletal striated muscles, hand tremors, inhibition of motor activity.
3. Heart and blood vessels - decreased levels of systemic blood pressure (hypotension).
4. Skin - increased sweating (hyperhidrosis), rashes on the skin, flat lichen (develops in extremely rare cases), lupus-like rashes on the skin.
5. Allergic phenomena - rash and itching, hives, soft tissue swelling with localization in the genital area and face (angioedema).
6. Metabolism is an increase in body weight.

If the first negative pathological symptoms occur while using this medication, taking the tablets should be stopped and consult a specialist.

Special recommendations for use

Before prescribing this drug, the doctor must pay attention to some rules for its use:

1. With prolonged use, it is recommended to conduct regular laboratory monitoring of the functional state of the liver and kidneys, as well as to observe the picture of peripheral blood.
2. A medication in athletes can provoke false positive anti-doping control results.
3. A few days before skin tests for allergies, the drug should be discontinued, since it can level a positive result. This is usually associated with the presence of an antihistamine anti-allergic effect in the medicine “Cinnarizine”.
4. A medicine can enhance the effects of alcohol and sedative medications.
5. Patients with Parkinson's disease "Cinnarizine" are prescribed only in cases where the intended benefit is higher than the potential risk.
6. During the therapeutic course, it is recommended to refuse to perform potentially dangerous activities that require a high concentration of attention and the speed of mental reactions.

Overdose symptoms

The maximum number of Cinnarizine tablets per day should not exceed nine. In case of an overdose, symptoms arise that are similar to adverse reactions from the use of this medication, only with an enhanced effect. In this case, symptomatic therapy is carried out, since there is no specific antidote for this drug.

It is important to comply with the indications for use.

The price of Cinnarizine

The average price of one package of medication varies between 30-40 rubles. It depends on the region and the pharmacy network.

Indications for use of "Cinnarizine" and analogues often coincide.

Analogues of this medication

Cinnarizine analogue medications are:

1. Mexidol is a domestic product that is prescribed for impaired brain activity. The drug improves memory, is indicated for patients with cardiac ischemia, with arterial hypertension, acute vascular conditions.
2. Omaron is one of the best analogues, which includes cinnarizine and piracetam. Indications for use with the funds are completely identical. It treats diseases of the central nervous system and can be prescribed even to children with low intellectual development.
3. “Betagistin” is a practically harmless medicine produced in Belarus, which is indicated for dizziness, fainting, inability to concentrate, paresthesia, etc.
4. Cavinton is a Hungarian medicine whose effect is aimed at stabilizing cerebral circulation.
5. "Enap" - production of Slovenia. The medication is prescribed for hypertension, heart failure, ischemic myocardial disorders, angina pectoris.
6. "Tanakan" is an Italian medication that is used for discirculatory encephalopathy, impaired attention, memory, sleep, and intellectual abilities. In addition, it is indicated for the treatment of sensorineural disorders in asthenic conditions (depletion of the body due to psychogenic, traumatic and neurotic).

Drug Reviews

Despite the fact that this medicine has a very low cost and simple composition, it is in great demand in the pharmaceutical market. This is due to the fact that the medicine rarely causes adverse reactions, but acts quickly and purposefully.

Testimonials of patients indicate that “Cinnarizine” is easily tolerated by the body, rarely causes unwanted side effects and successfully fulfills its intended purpose - to improve blood supply to the brain. This effect was confirmed not only by diagnostic measures, but also by the well-being of patients who observed multiple beneficial effects, among which: improved memorization not only in adults but also in children; elimination of the symptoms of vegetative-vascular dystonia, anxiety disorders, normalization of the condition after various head injuries and after strokes, as well as with symptomatic therapy of such phenomena as dizziness, tinnitus, migraine, cephalgia and much more. Such an extensive list of indications for the use of Cinnarizine.

Reviews of specialists characterize this medication as simple and effective, but many doctors prefer to prescribe more modern drugs with a combined effect to their patients. "Cinnarizine", according to them, can only be used in cases of minor manifestations of certain pathological processes, and this tool is also well suited for complex therapy. In more complex cases, with a severe course of the disease, they prefer to prescribe other systemic medications that are more effective than this.

We examined the indications for the use of Cinnarizine tablets.