Some diseases of the throat and larynx require special treatment. For example, with serious purulent and bacterial infectious processes, special medications are recommended that actively eliminate the focus of inflammation.
"Dioxidine" is an antibiotic that belongs to the quinoxaline group. It is applied in many branches of medicine.
Structure
The medicine is dispensed from pharmacy points in the form of a solution that is intended for intracavitary and external use. The drug has a concentration of one percent and is dispensed in ampoules of transparent glass with a volume of ten milliliters. The contents of the ampoule are sterile, the solution may have a yellow or green color.
The main active ingredient of "Dioxidine" is hydroxymethylquinoxalindioxide. One ampoule of the drug contains one hundred milligrams of the active trace element. Water for injection acts as an additional substance. Does Dioxidin Gargle Use? Let's try to figure it out.
Pharmacological actions
The medication is an antibiotic with a wide spectrum of exposure, it is considered a derivative of quinoxaline. The active microelement has a pronounced chemotherapeutic effect in relation to infectious processes that are caused by Pseudomonas aeruginosa, as well as vulgar protea, dysentery bacillus, Salmonella, streptococcus, Klebsiella. The drug is active even against those viruses that show resistance to antibiotics and chemotherapeutic drugs.
With prolonged use of Dioxidin, bacteria can develop immunity and resistance. With intravenous use of the drug, the dosage prescribed by the medical specialist must be strictly observed.
When applied externally as a means for treating wounds and purulent inflammations, it helps to quickly clean the surface of crusts and exudate, activates the processes of restoration and epithelization of damaged tissues.
Indications
Dioxidin is recommended for patients for the treatment and prophylactic purposes of the following diseases and ailments:
- Inflammation caused by pathogenic microflora.
- Wounds.
- Trophic ulcers.
- Burns of varying degrees.
Intracavitary use of the drug is prescribed for diseases such as:
- Peritonitis (inflammation of the parietal and visceral sheets of the peritoneum, which is accompanied by a severe general condition of the body).
- Abscess of the lung (purulent-destructive limited process in the lungs).
- Cystitis (inflammation of the bladder).
- Mastitis (inflammation of the breast).
- Phlegmon (acute diffuse purulent inflammation of the cellular spaces, unlike an abscess, does not have clear boundaries).
- Postoperative wounds.
- Complicated otitis media (ENT disease, which is an inflammatory process in the ear).
- Complicated sinusitis (inflammation of the maxillary sinuses).
- Sinusitis (damage to the mucous membrane of the sinuses).
- Tonsillitis (inflammation of the tonsils).
- Pharyngitis (acute or chronic inflammatory process localized in the pharynx, affecting its mucous membrane and deeper layers).
- Laryngitis (an inflammatory process in the mucous cavities of the larynx).
Contraindications
"Dioxidine" can be used only as directed by a doctor. Before treatment, you must thoroughly familiarize yourself with the instructions for use, since the drug has the following prohibitions:
- Individual intolerance to the drug.
- Pregnancy and lactation.
- Adrenal cortex insufficiency.
- Failures in the kidneys.
- Acute renal failure.
- Children's age up to twelve years.
How to use the drug?
The drug is usually prescribed to people in a stationary location. "Dioxidine" is used in many branches of medicine both externally and internally.
If necessary, intravenous administration, the contents of the ampoule are diluted to the desired concentration with a solution of sodium hydrochloride. The dosage and duration of the course of treatment is determined by the attending doctor depending on the diagnosis and clinical signs.
Therapy of wound surfaces
If it is necessary to treat open festering or poorly healing wounds, lotions with the drug are used. To do this, gauze is moistened with a solution and applied to the wound surface. Deep damage is tightly plugged with gauze turundas, which are also moistened with Dioxidine. In the presence of drainage, up to one hundred milliliters of medicine is administered daily several times a day as an antiseptic into the damaged cavity.
For the treatment of wounds provoked by osteomyelitis, the affected area of the skin is first treated with a 0.5 percent solution, and then gauze is applied.
The drug can be used for prophylactic purposes of the occurrence of postoperative complications. To do this, each wound is treated with "Dioxidine". In the absence of individual intolerance, this medicine can be used for up to two months with normal tolerance.
Gargling "Dioxidine": how to dilute the solution correctly?
It is necessary to buy a one-percent solution with a concentration of active trace element 0.01 grams at the pharmacy. The medication effectively eliminates a huge number of pathogens, but it can lead to the appearance of negative side effects. Therefore, therapy with "Dioxidine" should be carried out, as a rule, in a hospital setting.
Gargling is less dangerous than injecting the drug into a vein, but even with this use, the occurrence of adverse reactions cannot be ruled out, since the drug is absorbed through the mucous membranes, penetrates into the plasma, and then excreted with urine.
Dosage
According to the instructions for the use of "Dioxidine" it is known that for the greatest effectiveness of therapy it is important to comply with the dosage and not exceed it. For irrigation of the throat, a 1 and 0.5 percent solution of the drug is used.
One ampoule must be diluted in one hundred milliliters of water (ten milliliters of solution per hundred milliliters of liquid). It is important to use boiled water or pharmacy saline. If the ampoule with a volume has a volume of 20 ml, then the liquid needs to be twice as much.
The resulting solution is not recommended to be stored. It is usually done before use. The frequency of rinsing is determined by the attending doctor, depending on the disease.
According to the instructions for use, "Dioxidine" for gargling can not be used more often than three times a day.
Adverse reactions
Against the background of drug treatment in humans, the following negative effects may appear:
- Chills.
- Headaches.
- general weakness.
- Cramps.
- Allergic reactions.
- Skin tightness.
- Dryness.
- Rash.
- Swelling.
In severe situations, the patient may experience angioedema and anaphylaxis.
Overdose
With prolonged use of the Dioksidin solution intravenously or into the cavity, signs of poisoning are likely to appear, which are manifested in the suppression of the kidneys and the malfunction of vital organs.
If you accidentally introduce too large dosages of the drug, a person needs to remain under the supervision of a doctor. If necessary, carry out symptomatic therapy.
Features
The medication is intended only for the treatment of adult patients. Before using the solution, a tolerance test should be done. In the absence of adverse reactions within four hours, the medicine can be used for treatment. It is necessary to use "Dioxidin" for gargling according to the instructions.
"Dioxidin" is prescribed only in extreme situations in the absence of pharmacological action from taking antibacterial drugs from the group of cephalosporins, carbapenems.
For people with chronic kidney diseases, the medication concentration is selected individually.
When storing "Dioksidina" ampoules for gargling in the refrigerator, sediment may precipitate. In this situation, before starting treatment, I heat the ampoule until the crystals completely disappear. Next, the solution must be cooled to the patient's body temperature. If the precipitate appears again, the drug must be discarded, even if its period is still normal.
Analogues of "Dioxidine"
The following medicines are considered similar in their pharmacological effects to the solution:
- Gatifloxacin.
- Ofloxin.
- Trinefron.
Before changing the prescribed drug with its generic, it is important for a person to consult a medical specialist, since not all of these drugs have the same pharmacological activity as Dioxidin.
How to store the drug?
According to reviews, “Dioxidin” for gargling is dispensed from drugstores strictly according to a prescription from a medical specialist. The solution must be kept in a dark, cool place, inaccessible to children.
In case of violation of the integrity of the ampoule or the occurrence of sediment, the drug is not recommended. The cost of "Dioxidine" varies from 200 to 500 rubles.