Why are Aleron tablets needed? Instructions for use, indications for taking this medication will be described later. Also, from the article you will learn about whether it is possible to give the mentioned drug to children, whether it has contraindications, whether it causes side effects, etc.
Description, composition and packaging
What components does the Aleron medication contain? Instructions, a description of the drug report that its active substance is levocetirizine dihydrochloride. The drug also includes auxiliary components in the form of lactose monohydrate, corn starch, magnesium stearate, sodium starch glycolate (type A), colloidal silicon dioxide and microcrystalline cellulose.
In what packaging can I buy Aleron? The instructions for this medicine are enclosed in a cardboard box. It also contains blisters with white and round tablets in a film shell.
Pharmacological features
What features does the Aleron medication have? The instruction for use reports that it is an antiallergic agent. It belongs to the group of antihistamines of the third generation.
The active component of the drug is able to provide anti-inflammatory, antipruritic, antiexudative and anti-allergic effects. Also, this drug has a pronounced antihistamine effect.
Operating principle
How does the drug "Aleron"? The instruction states that levocetirizine is able to block peripheral H1-histamine receptors, as well as prevent the release of histamine due to stabilization of mast cell membranes.
According to experts, the medication in question has no effect on M-cholinergic and serotonin receptors.
To achieve a therapeutic effect, the amount of levocetirizine is half as much as cetirizine. This is due to the fact that the first component forms a more pronounced connection with receptors.
After taking the drug, the production of chemokines decreases. Chemotaxis is also inhibited, the formation of pro-inflammatory cytokines is reduced, the adhesion of eosinophils and the expression of molecules are slowed down.
Under the influence of the drug, the release of IgE-dependent histamine, leukotriene C4 and prostaglandin D2 is reduced. In addition, the drug inhibits the thrombocyte activating factor of the skin.
Drug properties
What are the properties of the drug "Aleron"? The instruction reports that this medication noticeably alleviates the severity of symptoms of various allergic reactions (for example, allergic rhinitis).
Patients who regularly suffer from seasonal allergies can safely use this tool to improve their well-being, as well as to prevent the appearance of unpleasant symptoms.
According to experts, the medication in question is effective in bronchial asthma and cold urticaria. At the same time, its active component does not have a toxic effect on the heart, and also does not inhibit the central nervous system.
Pharmacokinetic indicators
Is it possible to take the Aleron drug at the same time with food? The instruction says that food does not have any effect on the absorption of this medication (to some extent, it can reduce the rate of absorption).
The drug is absorbed almost immediately from the digestive tract. Its bioavailability level is 100%. The maximum concentration of the main substance in the blood is observed after 50-60 minutes. With plasma proteins, the drug binds to 90%.
Only a small part of the drug is metabolized in the liver. As a result of this, an inactive metabolite is formed. The half-life of Aleron is 9-10 hours. Within four days, it is completely excreted through the kidneys and intestines.
Indications for use
Why is the Aleron medication (tablets) necessary? The instruction reports that this drug is prescribed for the treatment and prevention of allergic manifestations, which can be both acute and chronic.
So, the drug in question can be used for diseases such as:
- hives;
- allergic rhinitis;
- hay fever;
- angioedema ;
- allergic dermatoses, which are accompanied by a feeling of itching, burning, as well as rashes on the mucous membranes and skin;
- conjunctivitis.
Contraindications
What contraindications does the Aleron medication have? Instructions for use (for children there are restrictions) reports that this product should in no case be given to a child under 6 years of age. Also, the drug should not be prescribed in the following conditions:
- severe renal failure;
- a high level of patient sensitivity to the constituent components of the drug, as well as to piperazine derivatives;
- impaired absorption of glucose and galactose;
- galactose intolerance.
The drug "Aleron": instructions for use
Aleron tablets should be taken only according to indications. They are prescribed for adult patients, as well as children from six years.
The drug is taken orally with a normal liquid. The duration of the course of therapy, as well as the dosage of the medication, is determined only by the doctor, depending on the diagnosis.
Usually antiallergic drug "Aleron" is prescribed one tablet once a day. The daily dose of this medicine should not exceed 10 g.
According to the attached instructions, with short contact with an allergen, therapy with this drug must be continued for a week. If the patient suffers from hay fever, then the course of treatment can last up to one and a half months. In case of acute need, treatment is extended to six months.
Similarly, you must take the drug "Aleron Neo."
The instructions attached to the medicine informs that for people diagnosed with renal failure, the dosage must be adjusted. With impaired liver function, the same dosing regimen is practiced as in ordinary people.
Adverse reactions
What adverse reactions does the drug Aleron cause? The instruction (for children and adults) reports that this medication may contribute to the appearance of the following effects:
- feeling of a strong heartbeat;
- hepatitis;
- fatigue, headache, aggressiveness, drowsiness, anxiety, weakness, cramps;
- visual impairment;
- dry mouth and nausea;
- swelling and anaphylaxis;
- dyspnea;
- abdominal pain, myalgia and weight gain;
- urticaria, pruritus, and rash.
Overdose Signs
When taking high doses of the drug, patients experience severe drowsiness or, conversely, a state of overexcitation, followed by drowsiness. When observing such symptoms, the drug should be discontinued. The patient must be prescribed gastric lavage, as well as give him enterosorbent.
Drug interaction
With the simultaneous administration of levocetirizine and drugs, whose metabolism is directly related to the cytochrome P 450 system, no interaction is observed. However, with repeated administration of theophylline, the clearance of levocetirizine may decrease to some extent.
It is not recommended to combine the Aleron medication with sedative drugs.
Levocetirizine does not affect the intake of ethanol.
Special recommendations
According to the instructions, the medication in question is prescribed with extreme caution to the elderly, as well as to those who suffer from renal failure.
While taking the antiallergic drug Aleron, the patient is not recommended to drive vehicles and interact with complex mechanisms.
Pregnancy and lactation
There is no information on the use of the drug "Aleron" during pregnancy. Therefore, during this period it should be prescribed with extreme caution.
Levocetirizine passes into breast milk. In this regard, for the period of its use, it is necessary to stop breastfeeding.
Analogs and price
There are many drugs that can replace the Aleron medication. These drugs include the following: "Aleron Neo", "Gletset", "Alerzin", "Xizal", "Ceser", "Tsetrilev" and so on.
The listed drugs have a similar effect. However, they should be used only as directed by a specialist.
As for the cost, the drug in question is not very high. It is possible to buy Aleron tablets for 220-240 rubles.
Reviews about the antiallergic drug
The drug "Aleron" is not a very popular remedy. Therefore, reviews about it are extremely rare. From those that are available, we can safely conclude that this medication completely copes with the task. A single dose of tablets allows you to quickly and effectively remove all the symptoms associated with allergies. The drug significantly alleviates the condition of patients, and also prevents the appearance of unwanted reactions.
Among the negative reviews, there are often those that state that the medication in question quite often causes side effects.