Anthelminthic drugs are medicines that are designed to remove helminths from the human body. Depending on the class of helminths, such medications are divided into three groups. They adversely affect roundworm, pinworms and so on.
The most effective anthelmintic drug is the piperazine medication. Price, reviews and how to use it are presented below.
Composition, shape, packaging
What form is inherent in a drug like piperazine? Patient reviews report that this tool can be purchased in the form of tablets that are contained in contour cells. Their main component is piperazine adipate. In addition to it, the composition of the medication includes such additional compounds as calcium stearate and starch.
Pharmacodynamics of the drug
What features are characteristic of a medication such as piperazine? Instructions for use, reviews of experts claim that this is an anthelmintic intended for the treatment of ascariasis and enterobiasis.
This medication adversely affects individuals of pinworms and roundworms of all sexes, both immature and sexually mature. It paralyzes the muscles of nematodes and disrupts the system of their neuromuscular transmission.
With a single dose of tablets, the effectiveness of deworming is about 93-95%. When reusing the product, this value reaches 100%.
Due to the fact that this medication is not able to affect the shell of roundworm, but only causes paralysis of their muscle tissue, there is completely no chance of absorption of toxic decomposition products of worms.
It cannot be said that when infected with other nematodes, as well as with cestodoses and trematodoses, this medicine is ineffective.
Kinetic properties
Is the piperazine anthelminthic drug absorbed? Reviews report that this remedy is absorbed very quickly from the intestines. It is secreted from the human body through the kidneys.
Indications
In what cases is the most effective active ingredient of the drug, like piperazine adipate? Reviews of experts report that this tool is intended for the treatment of:
Contraindications
When should you not take a substance such as piperazine adipate? Reviews say that it is contraindicated in the presence of allergic reactions in the patient. Also, the medication in question should not be used for nephritis, epilepsy, organic lesions of the central nervous system, chronic renal or hepatic insufficiency.
Method of administration and dosage of medication
The drug "piperazine" for children (reviews of tablets will be presented below) is allowed to prescribe. However, this medicine should be taken only for strict indications.
According to the instructions, with ascariasis and enterobiasis, this medication is used twice a day, for two consecutive days (although there may be other regimens). Do this one hour before a meal or 60 minutes after it.
A single dosage for children under one year is 200 mg, for infants 2-3 years old - 300 mg, 4-5 years old - 500 mg, 6-8 years old - 750 mg, 9-12 years old - 1 g, and 13-15 years - 1.5 g.
For adult patients and adolescents from 15 years of age, the dose of the drug should be 1.5-2 g.
The course of treatment with this tool, as a rule, should last for five days. According to experts, this medication is taken in cycles (three) at seven-day intervals.
Between courses it is necessary to do enemas (at night) with sodium bicarbonate and water (for 250 ml of water ½ dessert spoon of soda).
For babies, the enema volume includes up to 3 glasses of fluid, and for adults - up to 5.
It should also be noted that the drug in question is often used to treat farm and domestic animals. According to the instructions, for them, the medication is indicated for toxascaridosis, uncinariosis, hookworm and trichocephalosis.
Side effects
Piperazin anthelmintic tablets, reviews of which are ambiguous, can cause adverse reactions such as:
- hallucinations, ataxia, blurred vision, dizziness, nystagmus, headache, paresthesia, vomiting, chorea, euphoria, impaired coordination, tremor;
- skin rashes, including erythema multiforme, urticaria, purpura, as well as bronchospasm, Steven-Johnson syndrome, itching, arthralgia, fever;
- nausea, drowsiness, areflexia, weakness, spastic epigastric pain, diarrhea, cramps.
The risk of such effects, including neurotoxic nature, is significantly higher in people suffering from renal failure.
Special recommendations
Therapy with this tool does not require a specialized diet, as well as any other human preparation. With a tendency to constipation, laxatives are prescribed to the patient.
In the treatment of enterobiasis , a strict hygiene regime must be observed in order to improve the results of therapy.
It is permissible to conduct treatment with this drug on an outpatient basis.
Weakened people with anemia require careful medication.
The drug "piperazine": reviews
Unfortunately, there are not very many reviews about this tool. Experts attribute this to the delicacy of the problem. According to some patients, this tool effectively copes with its task. Analysis shows that the number of worms is significantly reduced after the first pill.
Also, the advantages of the drug in question include its cheapness (9-15 rubles), a convenient form of release and availability.