The local antibacterial and antifungal medicine, which is actively used in gynecological practice, is the drug Neo-Penotran.
Pharmacological properties
The active components of the drug - miconazole nitrate and metronidazole - determine its antiprotozoal, antibacterial effect. Metronidazole inhibits the reproduction of nucleic acids of microorganisms, which leads to the destruction of their DNA and death. Miconazole disrupts the synthesis of elements of the cell membranes of fungi, which causes their destruction.
The tool has activity against anaerobic bacteria, trichomonads, pathogenic fungi, including the genus Candida, garganella, anaerobic streptococci. As the review indicates, Neo-Penotran effectively fights some gram-positive bacteria.
Release form and analogues
A product is produced in the form of vaginal suppositories, which contain from 100 to 200 mg of miconazole nitrate, as well as from 500 to 750 mg of metronidazole. The “Neo-Penotran Forte-L” analogue, in addition to the listed substances, contains 100 mg of lidocoin. There are no drugs that exactly copy the Neo-Penotran formula. The closest thing is the Klion-D 100, which contains the same active components, but in different volumes.
Indications for use
Suppositories are prescribed for topical treatment of mixed vaginal infections, bacterial vaginosis. The drug is used for vaginal candidiasis, trichomonas vulvovaginitis.
Contraindications
As the review shows, Neo-penotran cannot be used for severe abnormalities in the liver, porphyria, ailments of the nervous system, and violations of hematopoiesis. Suppositories are not prescribed for hypersensitivity to active elements, in early pregnancy, children and adolescents under 14 years of age. In the 2nd and 3rd trimesters, the drug is used strictly according to the indications. During lactation, if treatment is necessary, it is necessary to stop breastfeeding.
Candles "Neo-penotran": instructions, price
The medication is administered once a day in the evening. The course of treatment is a week. With recurrent vaginitis, the drug must be used twice - in the morning and in the evening. Therapy is carried out for two weeks. With a longer use, as indicated by the review, Neo-penotran may cause signs of an overdose. These symptoms are manifested by pain in the epigastrium, stomatitis, nausea, a metallic taste in the mouth, and itching. You can buy Neo-Penotran candles, the price of which is 678 rubles, in a pharmacy without a prescription.
Side effects
The drug can provoke negative reactions of the body, which are similar to signs of an overdose. According to the recall, Neo-Penotran can cause itching, burning, or irritation of the vaginal mucosa. In addition, dry mouth, abdominal pain, loss of appetite, diarrhea, metallic taste are observed. These symptoms disappear after the end of therapy. In rare cases, from the nervous system there are psycho-emotional disorders, headache, ataxia.