From the article we learn the international name "Mexidol". Also consider the instructions for use with the drug.
"Mexidol" is an antioxidant that is included in the category of new generation drugs. Its action is aimed at normalizing the blood circulation of the brain, both in adult patients and in children. The drug has a nootropic effect, which consists in protecting brain cells from free radicals, as well as in normalizing metabolism. Mexidol is widely used in neurological practice.
The nootropic effect of the drug activates the brain's mental activity, increases the ability to master information and learn, and also has a beneficial effect on the quality of memory. Acting as an antioxidant, Mexidol protects cells from excessive oxidation, reduces the harmful effects of free radicals on the body and increases the resistance of tissues and organs to oxygen deficiency.
What is the international name Mexidol? About it - further.
Composition and form of release
It is produced both in tablet form and in the form of a solution for injection. The active component of the drug is ethylmethylhydroxypyridine succinate.
The international name is Mexidol in Latin Mexidol.
The international trade name in Russian, Mexidol, remains so.
The international nonproprietary name of Mexidol is absent.
One tablet contains:
- 125 mg of the active antioxidant component.
- Auxiliary components: povidone, magnesium stearate, lactose monohydrate, titanium dioxide, hypromellose, polyethylene glycol, triacetin.
Solution
In the form of a solution, the drug is produced in ampoules of 2 and 5 ml. The solution is colorless, transparent, intended for administration intramuscularly or intravenously. The content of ethyl methylhydroxypyridine succinate in one milliliter of the solution is 50 mg. In addition, water for injection was added to the solution.
Vacation in pharmacies and cost
The drug is dispensed in pharmacies without a prescription, however, to take it, you must consult your doctor.
The cost of the drug is on average about 300 rubles for one package of tablets and 400 rubles for a small package of ampoules.
The properties
“Mexidol” (international name Mexidol) is prescribed when it is necessary to stimulate the blood supply and metabolic processes in the brain. The main properties of the drug are as follows:
- Membrane Protective.
- Antioxidant.
- Anticonvulsant.
- Antihypoxic.
- Hypolipidemic.
- Nootropic.
- Anxiolytic.
After a course of treatment with Mexidol (the international Latin name Mexidol) in any form, including injections, the following effects of the drug are observed:
- Increased dopamine levels.
- Normalization of metabolic processes.
- Normalization of blood supply to the brain.
- Improving blood microcirculation.
- Normalization of rheological parameters of blood.
- Decreased platelet aggregation.
- Activation of energy production by mitochondria of cells.
- Stabilization of cell membranes.
- Normalization of metabolic processes in the defeat of some parts of the myocardium by coronary artery disease.
- Decrease in the volume of necrotic lesions.
- Increased blood circulation in areas of the myocardium undergoing ischemia.
- Stabilization of the membrane of blood postcellular structures, namely platelets and red blood cells during hemolysis.
- Decrease in the level of cholesterol of the general type.
- Decrease in indicators of low density lipoproteins in the blood.
- A decrease in the intensity of the manifestation of symptoms of pancreatogenic toxemia type (blood intoxication).
- Reducing the intensity of manifestations of endogenous poisoning caused by acute pancreatitis.
- Increased compensatory activity of aerobic glycolysis.
- Against the background of oxygen starvation of brain cells, the antioxidant reduces the degree of suppression of oxidation processes in the Krebs cycle.
- Increased levels of creatine phosphoric acid and adenosine triphosphate.
- Reducing the severity of complications with reperfusion syndrome, provoked by coronary insufficiency in acute form.
- Recovery and improvement of electrical conductivity and conduction of the heart muscle.
Another important property of the medication is to eliminate the symptoms that accompany withdrawal symptoms.
So it is said in the instructions to "Mexidol" (international name "Mexidol").
Indications
It is widely used in medical fields such as cardiology, neurology and psychiatry. The following pathological conditions are indications for prescribing the drug:
- Panic attacks.
- Cognitive impairment as a result of cerebrosclerosis.
- Withdrawal syndrome, psychopathy.
- Intoxication with psychotropic drugs in acute form.
- Neurasthenia after intense physical exertion.
- Complications after injuries to the brain and concussions.
- Encephalopathy in acute or chronic form.
- Dysfunction of the autonomic system.
- Neurosis-like condition.
- Acute coronary circulation disorder in combination with other drugs.
- In the field of surgery, the drug is prescribed in the postoperative period, as well as during recovery from inflammation of the abdominal cavity and pancreatitis.
- As a prophylactic in transient ischemic brain disease, as well as to eliminate residual symptoms after a stroke.
- Prevention of planned excessive loads, both physical and mental.
Contraindications
Mexidol is not prescribed in the following situations:
- acute renal failure;
- hypersensitivity to the components that make up the drug;
- children under the age of 18;
- the period of bearing a child and breastfeeding.
Severe abnormalities in the liver can also become a reason to limit the intake of Mexidol. The trade and international name of the drug has already been considered, so you can move on to other equally important issues.
Instruction manual
The drug in tablet form is taken three times a day for 1-2 tablets. The maximum daily dosage is 800 mg, or 6 tablets. The course of therapy lasts from two to six weeks. When eliminating the withdrawal symptoms caused by alcohol intoxication, it will be necessary to take tablets for 6-7 days, while the dosage should be reduced by the end of therapy.
In some cases, it is required to begin treatment with minimum dosages of 1-2 tablets in the morning and evening, gradually increasing the dose to achieve positive dynamics.
Patients with coronary heart disease “Mexidol” is prescribed according to the standard scheme, however, the duration of therapy will be up to two months. Repeated treatment is recommended in the fall or spring.
The Mexidol solution is administered intravenously or intramuscularly. For infusion, the drug is diluted with saline. The method of intravenous administration can be jet or drip, depending on the prescription of the doctor. The maximum daily dosage of the drug in case of injection should not be more than 1200 mg.
Adverse reactions
While taking Mexidol (international name in Latin Mexidol), some adverse reactions may occur, including:
- violation of taste perception;
- dry mouth
- dyspeptic disorders;
- symptoms of an allergic reaction.
When these symptoms appear, you do not need to cancel the drug. Adverse reactions will go away on their own and will not require specific additional treatment. To eliminate the metallic taste in the mouth during the intravenous administration of Mexidol (international name in Latin Mexidol), it is necessary to reduce the rate of administration of the drug.
Overdose
With a significant excess of the prescribed therapeutic dosages of the drug in the case of using a solution, severe drowsiness occurs. If this symptom appears, discontinue the administration of the drug and conduct symptomatic therapy.
In medical practice, there are cases when a severe form of hypersensitivity to sulfites contained in the drug occurs. This is especially true for patients with a history of bronchial asthma.
Against the background of treatment with Mexidol, it is not recommended to drive vehicles and carry out work that requires an increased concentration of attention and a high speed of psychomotor reactions.
Analogs
The most popular structural analogues of Mexidol include the following drugs:
- Mexiprim;
- Mexidant
- "Cerecard";
- Neurox
- Mexifin;
- Mexicor;
- "Medomeksi".
On average, the cost of these analogues is 50 rubles per ampoule.
A group of drugs is also singled out, which includes various active components, but they have a similar effect on the patient’s body as Mexidol. These drugs are:
- "Glycine";
- "Instenon";
- Nootropil;
- Cortexin;
- Piracetam
- "Antifront";
- Cavinton
- "Actovegin";
- "Armadin."
Some therapeutic regimens prescribe an integrated approach involving the simultaneous administration of several drugs, the main thing is that they are not structural analogues. Thus, it is possible to simultaneously act on several pathological mechanisms at once.
The medication is an effective drug to eliminate various disorders in the blood circulation and supply the brain with oxygen. The drug shows especially good results as a prophylactic.
The article considered the international name "Mexidol" and instructions for use.