"Pantocalcin": instructions for use, analogues and reviews

In this article, we consider the instructions for "Pantocalcin" for children.

The medicine is prescribed quite often. The drug is a nootropic substance that has anticonvulsant, antidysuric, cerebroprotective and other effects. This medication improves metabolism in cells and tissues, prevents the occurrence of hypoxia.

Pharmacological activity

A fairly wide spectrum of action of the medicament in question is due to the presence of hopantenic acid in its composition. The drug has a direct effect on the GABAA-receptor-channel complexes, enhances the inhibitory processes in the GABA-ergic synapse. There is also some evidence of the direct effect of this medication on glutamate, norepinephrine, serotonin, dopamine and neurotransmitter systems. As a result of the activity of hopantenic acid, glucose metabolism is normalized, in particular, its utilization in the cerebral cortex, hypothalamus, subcortical ganglia, as well as in the cerebellum, is enhanced. This confirms the "Pantocalcin" 250 mg instruction.

In addition, the processes of regulation of the exchange of nucleic acids, stimulation of anabolic processes in the brain cells are carried out, including increasing the synthesis of RNA, ATP and protein. Hopantenic acid helps to reduce platelet aggregation, thereby contributing to the normalization of the passage of red blood cells through the microvasculature, improves the nutrition of brain neurons with oxygen, and under conditions of hypoxia significantly reduces the need for oxygen in tissues, thereby reducing the level of oxygen starvation. The drug produces a pronounced neuroprotective effect, and also affects the digestibility of tricarboxylic acids, resulting in improved energy metabolism in the body.

According to the instructions, “Pantocalcin” is used in childhood also because it helps to improve memory, perception, concentration, attention, intellectual functions, the ability to absorb information and learning. In addition, the medication has a mild sedative effect, reduces the incidence of spontaneous muscle activity, and reduces the child’s hyperactivity.

Due to the fact that hopantenic acid optimizes the conduction of nerve impulses and reduces motor excitability, a significant anticonvulsant effect is observed due to the use of this medication.

Pharmacodynamics

As the instructions for Pantocalcin indicate, in the digestive tract when taken orally, the medication in question is absorbed well, its highest concentration in the blood is observed after 60 minutes. The drug passes through the blood-brain barrier, and hopantenic acid can accumulate in the kidneys, walls of the stomach, liver and skin. The active substances of the drug are excreted from the body completely unchanged, within 48 hours, mainly by the kidneys.

Indications for use

What else does the instruction tell us? "Pantocalcin" is prescribed, as a rule, for various cognitive impairments that arise as a result of severe neurotic disorders, as well as organic brain damage. For children, the drug is used to treat the following pathologies:

1. Cerebral insufficiency in schizophrenia, with concomitant treatment with antipsychotics and antidepressants.
2. Consequences of previous neuroinfections and traumatic brain injuries, also in combination with other drugs.
3. Extrapyramidal hyperkinesis in pathologies of the nervous system of a hereditary nature (for example, hepatocerebral dystrophy).
4. Epilepsy, which inhibits mental processes. The treatment is carried out in conjunction with medicines that have an anticonvulsant effect.
5. Urinary disorders (e.g., daytime urinary incontinence, peremptory urination, enuresis, pollakiuria).

This information can be found in the instructions for tablets "Pantocalcin".

In addition, a pharmacological agent is recommended for use in reducing levels of mental and physical performance, as well as high psycho-emotional stress. The medication is used in cases of delayed intellectual and mental development, the clonic form of stuttering, hyperactivity, which could be triggered by a lack of attention, as well as to develop the correct perception and memorization of information.

According to the instructions, Pantocalcin for infants is prescribed, as a rule, from the first days of life with the following pathologies:

1. Perinatal encephalopathy.
2. Neurosis.
3. Epilepsy (with small seizures).
4. Cerebrostenic syndrome (oligophrenia).
5. Various forms of cerebral palsy.
6. Trembling limbs.
7. Cramps.

Dosage forms and composition of the drug

In accordance with the instructions Pantokaltsin is produced in the form of flat cylindrical white tablets with a chamfer and a risk. The active substance in its composition is calcium hopantenate, it is present in each tablet in an amount of 250 or 500 mg. Potassium starch, calcium stearate, talc and magnesium hydroxycarbonate are presented as additional components in the medicine. Tablets are packaged in packs containing 10 pieces or plastic cans of 50 tablets each. This will confirm the instruction.

Pantokaltsin syrup many want to find on sale, but it does not exist. In this case, you will be offered an analog.

Five contour packs or one jar are placed in a cardboard box, with instructions for use with Pantocalcin 250 mg.

Use of the drug in children under three years of age

The instructions for this drug indicate that giving it to a child under three years of age is not recommended. However, specialists often prescribe Pantocalcin medication to children in the first year of life and even to newborns. This is due to the fact that this medicine is produced exclusively in tablet form, as a result of which it is not very convenient to use it for infants. And this is the only reason why the use of the drug Pantocalcin in young children is not advised.

In the treatment of diseases in infants, it is preferable to prescribe a similar drug in the form of a syrup - Pantogam. Nevertheless, pediatric neurologists often prescribe Pantocalcin in the treatment of newborns, and there are special reasons for this. Firstly, unlike other medicines, this drug is the safest because it is a hypoallergenic medicine. This is confirmed by the instruction for Pantocalcin tablets.

Effects on the body

For a child, protein metabolism in the tissues and cells of the body is very important. The pharmacological agent Pantocalcin has a comprehensive effect on the brain, improves the activity of neurons and the metabolism in them, and restores the main brain functions. As a result of this, children develop faster, acquire practical skills and diverse knowledge, their intellectual and cognitive abilities increase. Also, the medication "Pantocalcin" 0.25 g for children according to the instructions is prescribed for inhibition of the central nervous system.

Use of the medication for hyperactivity

If during the period of prenatal life or in infancy a certain brain microdefeat has occurred, in the future the child may develop hyperactivity syndrome, which may be accompanied by distraction and impaired attention. At the same time, children are characterized by excessive mobility, uncontrollable behavior and the inability to concentrate on something. As a result of this, the child’s adaptation in the team is impaired; he cannot master knowledge and new skills. In order to eliminate hyperactivity in a child, neurologists often prescribe Pantocalcin to such children.

Use of medication for urinary incontinence

Against the background of some neurogenic disorders that are associated with neuromuscular pathologies in the work of the bladder, children may have urinary incontinence. In such cases, this medication also helps. It helps to optimize the functioning of the bladder and normalize urination.

Consider the method of application according to the instructions for the drug Pantocalcin.

Mode of application

The medicine should be taken after meals, thirty minutes later. The daily dosage for children is 1-3 grams, a single dose is 0.5 grams. On average, the course of treatment lasts about one to four months, and in certain cases it can increase up to six months. After this, a six-month break should be made, and then a second course of therapy with Pantocalcin.

The dosage for the child is usually selected by a specialist, taking into account the clinical picture of a particular disease. For infants, tablets are dissolved in a small amount of water. The drug, as already mentioned, has a pronounced nootropic effect, so its use should be carried out in the morning and in the afternoon (tablets should not be taken after 17 hours). As a rule, children, given their age, are given the following daily dosages: up to one year - from 0.5 to 1 gram, from a year to three years - from 1.5 to 2 grams, from three to fifteen years - from 2.5 up to 3 grams.

In case of urination disorders, a single dose is from 0.25 to 0.5 grams, and the daily dosage is determined by the calculation of 0.025-0.05 grams per kilogram of weight. The treatment course is one to three months. The use of a medication begins with minimal doses, gradually increasing them over seven days, then the maximum volume is taken, after which a slow dose reduction begins until Pantokaltsin is canceled.

Side effects

There is information that this drug almost never causes unwanted effects, so you can give Pantocalcin medication to children with complete confidence.

Contraindications

This medication should not be used in the treatment of children who have severe impairment of the functional properties of the kidneys, as well as those who suffer from hypersensitivity to hopantenic acid, as well as to other substances contained in this medicine.

Interactions with Other Medicines

The medication Pantocalcin has the property of enhancing the activity of some other nootropic drugs, as well as nervous system stimulants and medicines used for local anesthesia. In addition, the active ingredients of the drug prolong the effect of barbiturates. When a medication is used in conjunction with phenobarbital and antipsychotics, a decrease in the negative effects of the latter can be observed. The concomitant use of this drug with the preparations "Glycine" and "Xidiphon" leads to a mutual strengthening of pharmacological properties.

So it is said in the instructions for "Pantocalcin" 250 mg.

Analogues of the drug

The list of medicines analogous to this drug is very large, and the main ones that are most popular include:

• "Citimax";
• Pantogam
• PantogamActive;
• Semax
• Nooclerin
• Noofen
• "Somazin";
• Metsetam
• "Picamilon";
• Medotilin;
• Nootropil;
• Gopantam;
• Noopept;
• "Evrysam";
• Neuroxon;
• "Rekognan";
• Olatropil;
• Lira
• "Piracezin";
• Selank
• "Glycine";
• Neuronics
• "Ceregin";
• Neuro-Norm;
• "Calcium Hopentenate";
• Vinpotropil;
• Mebicabr;
• "Bifren";
• Cognum
• Entrop;
• "Gleazer";
• Lucetam
• Neupilept;
• Memotropil;
• Cerebral
• "Piratropil";
• Ceraxon
• "Delecitis";
• Anvifen
• "Elfunat";
• "Gliatilin";
• "Cereton".
• "Liposome Forte";
• "Tiocetam";
• Pramistar
• “Bilomag Forte”;
• Encephabol;

For analogues of Pantocalcin, we will not consider the instructions.

Reviews

The opinion of parents whose children underwent therapy with this medication is very mixed. There are both positive and negative reviews about the drug, which, on the one hand, gives a pronounced positive effect in the treatment of certain diseases of the nervous system, improving metabolic processes in the brain cells. As a result of this, a clear result is observed - children become calmer, cry less, shudder less from loud sounds, and begin to behave more adequately.

Older children learn the learning material better, they gradually develop the ability to concentrate more carefully on the learning process, and memorization of useful information improves. On the other hand, parents note the increased irritability of children at the beginning of therapeutic procedures, most often in the first week of taking the drug. At the same time, children experienced sleep impairment, increased tearfulness, irritability. After some time during treatment with Pantocalcin, such manifestations began to gradually disappear.

In general, parents are very pleased with this drug.

There are also reviews of adverse reactions from the use of this medication. Parents at the same time indicate that their children had minor rashes on the skin in the form of urticaria and slight redness, even though the instructions for use of this medication indicate that it is hypoallergenic and absolutely safe. No other adverse reactions from the child's body were found.

We reviewed the instructions for Pantocalcin tablets for children.