Amoxicillin is an antimicrobial agent with an extensive spectrum of action. To which series of antibiotics does Amoxicillin belong? The drug belongs to the 4th generation of semisynthetic penicillins.
The antibiotic is active against gram-positive aerobic bacteria:
- Streptococcus.
- Staphylococcus
In addition, the drug exhibits increased activity to gram-negative aerobic bacteria:
- salmonella;
- gonococci;
- meningococcus
- Escherichia coli;
- klebsiellam.
Why amoxicillin tablets?
Release form
According to the instructions for use, depending on the ailment, different forms of medication are prescribed. The basis of the drug is amoxicillin trihydrate. Additional substances include magnesium, sodium, polyvidone and others.
Forms of release of "Amoxicillin" are:
- Tablets.
- Capsules
- Suspension for oral administration.
- Solution for oral administration.
- Dry matter for injections.
The cost of the drug varies from 60 to 110 rubles. Why amoxicillin tablets?
What is Amoxicillin used for?
According to the instructions for use, the medication is used for bacterial infections that are provoked by pathogens sensitive to its action.
The range of indications for the use of the drug "Amoxicillin" includes:
- Salmonellosis is an intestinal infection that is triggered by salmonella.
- Dysentery is a bacterial intestinal infection that is caused by damage to the mucous membrane of the colon.
- Meningitis is an inflammatory lesion of the membranes of the brain and spinal cord.
- Endocarditis is a serious disease in which the inner membranes of the heart chambers are affected.
- Laryngitis is a lesion of the mucous membranes of the larynx, which is usually associated with colds or with infectious diseases such as scarlet fever and whooping cough.
- Sepsis is an infectious disease that develops with the progression and spread of the infectious process through the body through the blood.
- Sinusitis is an inflammatory lesion of the mucous membrane of the sinuses.
- Tonsillitis is an inflammatory lesion of the tonsils, which develops due to the influence of bacteria or viruses on lymphoid tissue.
- Pharyngitis is an acute or chronic inflammatory process localized in the pharynx, affecting its mucous membrane and deeper layers, as well as soft palate tissues, lymph nodes.
What cures Amoxicillin yet? The drug is also effective in the following pathologies:
- Otitis media is an infectious inflammatory process that is characterized by instant development and localization in the middle ear cavity.
- Pneumonia is an inflammation of the lung tissue, usually of an infectious origin with a primary lesion of the alveoli and interstitial lung tissue.
- Bronchitis - damage to the respiratory system, in which the bronchi are involved in the inflammatory process.
- Cystitis is an inflammation of the bladder, a widespread urological disease of the urinary system.
- Urethritis is an inflammation of the urethra (urethra) caused by damage to the canal wall by various bacteria and viruses.
- Gonorrhea is a sexually transmitted infection that causes damage to the mucous membranes of organs lined with cylindrical epithelium: the urethra, uterus, rectum, pharynx, and conjunctiva of the eyes.
- Cholecystitis - inflammation of the gallbladder - is one of the most common complications of gallstone disease.
- Cholangitis is an inflammation of the bile ducts.
- Peritonitis is an inflammation of the parietal and visceral sheets of the peritoneum, which is characterized by a serious condition.
- Enterocolitis - acute and chronic diseases of the digestive tract, characterized by inflammation of the mucous membrane of the small and large intestines.
- Erysipelas is a serious infectious disease, the external manifestation of which is a progressive lesion.
- Infected dermatoses are inflammatory diseases that affect the skin.
In combination with Metronidazole, the medicine is used to eliminate chronic gastritis or peptic ulcer.
Pharmacological effect
Amoxicillin is effective against a large number of pathogens, with the exception of penicillinase viruses.
Amoxicillin begins to act half an hour after use, and the drug lasts for eight hours, therefore, to maintain maximum concentration, the drug is prescribed three times a day.
After a certain period of time, the medication is partially excreted by the kidneys, liver and in small quantities with breast milk, therefore, nursing mothers are advised to stop breastfeeding the baby for the duration of therapy.
Pregnancy and breastfeeding
"Amoxicillin" crosses the placenta, in small amounts excreted in milk. If you need to use the drug while carrying a child, it is necessary to weigh the likely benefits for the mother and the potential risk to the fetus. With extreme caution, "Amoxicillin" should be used for breastfeeding.
During pregnancy, the drug can be prescribed according to the indications for inflammatory diseases. It is also used for bacterial infectious processes. But still, "Amoxicillin" in pneumonia in adult women during pregnancy can cause dysbiosis, allergic reactions, fungal infection.
Treatment
According to the instructions for use, the dosage of the drug is purely individual. The duration of therapy varies from 5 to 12 days:
- For oral use, a single dose of the active substance for adults and children from 10 years old (weighing more than 40 kilograms) varies from 250 to 500 mg, with a severe course of the disease - up to 1 gram.
- For children from 5 to 10 years, a single dose of the active component is 250 mg; at the age of 2 to 5 years - 125 milligrams; for children under 2 years, the daily dosage is 20 mg per kilogram of weight.
- For adult patients and children, the interval between doses is eight hours. In the treatment of acute uncomplicated gonorrhea - 3 grams once.
The treatment of acute otitis media is based on antibiotic therapy. "Amoxicillin" with otitis media, adults are prescribed at a dosage of 0.25-0.5 g three times a day. The duration of therapy is 10 days.
Situations in which the drug is prohibited to use
"Amoxicillin" is not prescribed for the following diseases and conditions:
- Increased Sensitivity.
- Seasonal allergic rhinoconjunctivitis is a chronic inflammatory disease of allergic etiology, in which the mucous membrane of the nasal cavity and conjunctiva of the eye is affected.
- Infectious mononucleosis is a viral disease that is accompanied by fever, damage to the lymph nodes, spleen and peculiar changes in the composition of the blood.
- Hepatic insufficiency is a complex of symptoms characterized by a violation of one or more functions of the liver, resulting from damage to its parenchyma.
- Lymphocytic leukemia is a blood disease in which, among the normal cells that make up the blood, cells with a pathological gene structure are born.
- Bronchial asthma is a chronic inflammatory disease of the respiratory tract, characterized by asthma attacks of varying duration and frequency.
- Exudative-catarrhal diathesis is an anomaly that is characterized by a tendency to infiltrative-desquamative changes in the skin.
- Lactation.
- With extreme caution, an antibiotic is used for kidney diseases, as well as a history of pregnancy and bleeding.
Can I drink "Amoxicillin" at a temperature
According to the annotation, antimicrobials are also prescribed for patients with fever. With the right selection of the drug, its use shows excellent results.
Is it possible to use Amoxicillin in a certain situation, it should be decided in conjunction with the attending physician.
In most cases, all of the above diseases are accompanied by an increase in body temperature. Patient responses confirm that Amoxicillin in SARS in adults improves the patient's condition in the first days of therapy.
Side effects
According to the instructions, when using Amoxicillin, the following negative effects are likely to occur:
- Anaphylactic shock is an allergic reaction of origin, a state of sharply increased body sensitivity.
- Rhinitis is a lesion of the nasal mucosa.
- Erythema - severe redness of the skin, which occurs due to the fact that the capillaries expand.
- Nettle rash - a skin lesion, dermatitis of an allergic etiology, which is characterized by the rapid development of severely itchy areas.
- Quincke's edema is an allergic reaction to the influence of various biological and chemical factors.
- Conjunctivitis is an inflammatory process that occurs on the mucous membrane of the eye.
- Joint pain.
- Fever.
- Dizziness.
- Depressive disorders.
- Stenosis is a persistent narrowing of the lumen of the hollow anatomical structure of the body.
- Peripheral neuropathies - a violation of the transmission of signals by the brain due to damage to one nerve or group.
When using Amoxicillin together with clavulanic acid, the following side effects may occur:
- Cholestatic jaundice is a condition in which the flow of bile into the duodenum and intestines is impaired due to a decrease in its synthesis or excretion.
- Epidermal necrolysis is a serious disease, accompanied by rejection of the surface layer of the skin and impaired functioning of the internal organs.
- Erythema multiforme is an acute inflammatory lesion in the skin or more often in the mucous membranes, which is characterized by a large number of elements of polymorphic rashes, as well as a predominantly cyclical course and a tendency to exacerbations and self-healing.
- Hepatitis is an inflammatory disease of the liver, usually of viral origin.
- Exfoliative dermatitis is a group of diseases in which the skin becomes inflamed, reddens, then blistering and peeling are noted.
What can replace Amoxicillin
The following medications are substitutes for Amoxicillin:
- Apo-Amoxi.
- "Ecobol".
- Amosin.
- "Augmentin."
- Amoxisar.
- Amoxiclav.
- Danemox.
- "Azithromycin".
- Hikontsil.
- "Flemoxin Solutab".
- E-Mox.
- Sumamed.
- Amoxillate.
- Bactox.
- Ospamox.
- Tysil.
It is not recommended to replace the drug with a similar one on its own. Be sure to coordinate the replacement with your doctor.
Alcohol Compatibility
Can I drink alcohol while taking Amoxicillin? With the simultaneous administration of alcoholic beverages with Amoxicillin, intoxication occurs. The consequences of this combination are as follows:
- Alcohol reduces the effectiveness of any antibacterial medication. Therapy becomes ineffective.
- Side effects of the drug in combination with alcohol are amplified.
- The medicine can provoke vomiting, increase irritability and irritability.
- Dry mouth appears, severe headaches and a change in taste. If these two substances enter the body, then there is a powerful effect on the central nervous system.
What storage conditions does the drug have
According to the annotation, the drug should be stored in a dark place, away from children, at a temperature not exceeding 25 degrees Celsius. Amoxicillin is suitable for 3 years. It is forbidden to use the medicine after the expiration date. The drug is dispensed from a pharmacy with a prescription.
Reviews about the drug
On the Web you can often find the responses of patients who talk about Amoxicillin, which heals almost any ailment, effectively reduces the temperature. Reviews are mostly positive about the medicine.
They note that after the start of therapy, the therapeutic effect manifests itself immediately, the medication is convenient for both adults and small patients for whom there is a suspension.
According to reviews that "Amoxicillin" treats, we can conclude that the most diverse diseases. In addition, as an advantage, it is mentioned that the drug can be taken while carrying a child. Opinions about the "Amoxicillin" of pregnant women, as a rule, narrate about its increased effectiveness and the rare development of adverse reactions.
Feedback from medical professionals is also positive. But doctors always warn that self-medication is strictly prohibited.
Amoxicillin is an effective medicine that eliminates many types of bacterial diseases. What does "Amoxicillin" treat? With laryngitis, sinusitis, pyelonephritis, tonsillitis, dermatitis, this medicine is often prescribed.
One of the main advantages of an antimicrobial agent is experts consider its acid resistance and bioavailability.
Eating food does not change the pharmacokinetic properties of Amoxicillin. As a result, the maximum concentration in the blood of the antibiotic reaches about an hour or two after taking the medicine.