In the article, we will consider the indications and reviews for Cortexin injections for children.
A drug is a nootropic drug that belongs to the category of protein bioregulators. The active substance of the same name in its composition is a complex of soluble polypeptide fractions that are extracted by vinegar extraction from the brain of cattle and pigs. This component overcomes the barrier between the central nervous system and the circulatory system, penetrates through the capillaries of the brain to nerve fibers and cells.

This allows the drug to protect neurons from the action of free radicals of oxygen starvation, to increase resistance to toxins. The medicine helps to improve brain functions, making it easier for the child to perceive and remember information, and his ability to concentrate is increased. In addition, Cortexin reduces the increased activity of epileptic centers, preventing convulsive phenomena, slows down the oxidation of fatty acids by oxygen, increases the survival of neurons with severe hypoxia, activates metabolic processes, and improves the functionality of the cerebral cortex.
In order to normalize brain activity, activate metabolic processes in its tissues and eliminate all kinds of neurological pathologies, this medication is often prescribed for children. Reviews about "Cortexin" are abundant.
The composition of the medication and the form of release
"Cortexin" is presented in only one dosage form - lyophilisate for injection. The drug is packaged in cardboard boxes, inside of which are 10 glass bottles with white or yellow powder, which can also look like a homogeneous porous white or yellow mass.
The main component of this powder are polypeptide fractions. Similar protein molecules with small mass and length are a complex soluble in water, and are called cortexin. Their volume in one bottle can be 5 or 10 mg. These substances are extracted from pigs and cattle.
Glycine was added to the drug as a stabilizer, the dose of which is 6 mg in 5 mg vials of the soluble complex and 12 mg in 10 mg vials.
Reviews for Cortexin for children and the price will be discussed below.
Mechanism of action
After the injection of the drug “Cortexin”, protein low-molecular molecules pass through the blood-brain encephalic barrier and have the following effects on the brain:
- Stimulation of nerve cells, due to which the balance of inhibitory and exciting mediators is normalized.
- Protection of neurons from all kinds of damaging factors, for example, from hypoxia, exposure to calcium ions and free radicals. This therapeutic effect is called cerebro- or neuroprotective. This develops the resistance of nerve cells to negative external influences, including stress and the use of certain psychotropic medications.
- The activation of metabolic processes in the brain tissues and the acceleration of recovery of nerve cells, as a result of which the functions of the central nervous system and its general tone improve.
- High efficiency when exposed to those parts of the brain that are responsible for the ability to work and learn new material. This effect is called nootropic and consists in improving thinking, attention and memory.
- Decreased convulsive activity in case of impaired brain function. As a result, the use of the Cortexin medication helps prevent seizures.
- Slowing down oxidative processes in the brain cells, that is, the drug acts as an antioxidant.
Reviews about Cortexin for children are mostly positive.
Indications for use in children
In childhood, the drug "Cortexin" is prescribed for the following diseases:
- traumatic brain injuries (including to eliminate their consequences);
- encephalitis or encephalomyelitis;
- speech delay;
- epilepsy;
- neuroinfections caused by certain bacteria or viruses;
- delayed psychomotor development ;
- circulatory disturbance in the brain;
- encephalopathy;
- hydrocephalic syndrome;
- problems with attention and memory;
- asthenia;
- cerebral palsy. According to reviews, "Cortexin" for children with ZRD is very effective.
The medicine can be used to treat children of any age, even infants in the first year of life. This tool is used even in premature babies, in the presence of serious indications, for example, with birth injuries, neuroinfections or hypoxia.
Reviews of Cortexin injections for children are presented at the end of the article.
Contraindications
This medication is not used in children with intolerance to its substances. There are no other contraindications to the use of this medication. However, if a child falls ill with a respiratory illness during the course of treatment, he should definitely contact a specialist who may cancel Cortexin therapy, since this medicine is not given for colds and flu, but is transferred to the treatment for the period of recovery.
Adverse reactions
According to reviews of Cortexin for children, in some cases, drug therapy provokes allergic reactions, for example, a rash and itching on the skin. If the injection site turns red, any rashes appear, and the child experiences pain and burning, it is necessary to consult a doctor.
Mode of application
The drug "Cortexin" is administered intramuscularly. Before making an injection, the lyophilisate should be diluted, and this is done immediately before administration. For such purposes, special water for injection is used, as well as sterile physiological solutions.
You can also dilute the medicine with 0.5% novocaine, but this solvent is used much less often. Despite the fact that it reduces pain, when diluted with an anesthetic, the effect of the drug “Cortexin” decreases, and the risk of allergic reactions increases. For this reason, the use of novocaine is recommended only in cases where the child does not tolerate injections or they are too painful for him. In this case, he should be allergic to novocaine. This is confirmed by the instructions for use for Cortexin injections for children. Reviews on this subject are available.
To dilute the drug powder, it is necessary to collect the solvent in a volume of 1-2 ml using a sterile syringe, remove the foil from the vial of the lyophilisate and puncture the cork. After this, the solvent is gently discharged inward so that foam does not form. In this case, a stream of liquid must be directed to the wall of the bottle, so that the liquid slowly drains onto the powder.
After that, removing the needle, you need to slightly shake the bottle until the medicinal powder is completely dissolved. When the fluid becomes clear and uniform, it is drawn into the same syringe and intramuscular injection is performed.
It should be remembered that for one injection, you need to dilute the entire lyophilisate, and only after that dial the desired volume of the drug solution. It is unacceptable to divide the powder into parts and dilute one of them.
Cortexin is recommended to be injected into the muscles of the thigh or shoulder. To reduce soreness, the injection should be performed with a thin needle and the medicine should be administered slowly. The next injection is made from the previous one at a distance of at least 1 cm.
According to reviews, “Cortexin” children under one year old is usually well tolerated.
Dosage of medication
For children weighing up to 20 kg, the dosage is calculated based on body weight. In this case, the number of kilograms is multiplied by 0.5. For such a baby, vials of 5 mg of the active ingredient are taken, 2 ml of solvent is diluted, and administered as much as necessary by weight of the child. The remainder of the drug is discarded.
Children weighing more than 20 kg "Cortexin" is prescribed 10 mg per day. In one bottle with the appropriate content of the active complex, dilute 1 ml of solvent.
The drug should be administered daily, once a day, ten days. Injections are recommended in the first half of the day, since the medication has some stimulating effect. After a ten-day course, you should take a break for several months, after which treatment can be repeated.
If, for a specific reason, the injection is missed, a double dose of the drug does not need to be administered. In such a situation, the course of therapy is simply prolonged so that 10 injections are obtained.
Drug interaction
The drug "Cortexin" does not adversely affect the body when used simultaneously with other drugs, so the limitations are met. However, the drug should never be mixed with other solutions than solvents in the same syringe. In cases where several types of injections are prescribed with different drugs, they must be administered by separate injections.
This is stated in the instructions for use for Cortexin for children. Price and reviews are of interest to many.
Analogues of the drug
Replace the drug "Cortexin" can be some other medications drugs with a similar therapeutic effect. These include:
- Kogitum. This medication in the form of a sweet solution with a banana flavor in ampoules is very popular with RRP, perinatal damage to the central nervous system, asthenia, neurosis and other pathologies. It can be used in children from 7 years of age.
- "Cerebrolysin." The therapeutic effect of this drug for intramuscular and intravenous injections is provided by peptides that are extracted from the brain of pigs. The drug is used in children with various craniocerebral injuries, metabolic or organic diseases of the brain. It is prescribed according to indications at any childhood.
- “Aminalon” is a medicine that is available in the form of tablets and has a therapeutic effect thanks to gamma-aminobutyric acids. The drug is prescribed for impaired attention, cerebral palsy, depression, mental retardation, motion sickness, drowsiness, etc. It is possible to use in children older than one year.
- Pantogam. This medicinal product in the form of syrup or tablets is used in any childhood and contains hopantenic acid in the composition . The medication is indicated for neurosis, mental overload, stuttering, impaired attention, enuresis and other pathologies.
- "Gliatilin" - a medical product that is made in the form of capsules and powder for injection, contains choline alfoscerate and is prescribed for cerebrovascular accidents, hydrocephalus, memory impairment, tics, birth defects of the brain, developmental delay and other disorders. The medication is also allowed to be used at any age.
- "Vinpocetine." This drug is produced in tablets and powders for injection and is used for encephalopathy in children, stroke, epilepsy, autism, etc. Use it only under the supervision of a specialist.
- Nootropil. The basis of this medication is piracetam. The drug is made in tablets, solutions and capsules. Assign to children from one year with brain injuries, reduced learning, stroke and other neurological pathologies.
- "Glycine" - a tablet drug that is used for stress, developmental delay, impaired attention. It is used in children from birth.
- Phezam is a capsule-based drug that includes two main components that affect the brain - piracetam and cinnarizine. The drug is recommended for children from five years old with motion sickness, decreased memory, tinnitus, asthenia and other disorders in the nervous system. Below are the reviews.
The price of Cortexin injections for children
The cost of this drug in the domestic pharmaceutical market is approximately 800 - 1300 rubles, which depends on the dosage of the drug in ampoules - 5 or 10 mg.
Efficiency
Many clinicians believe that the effect of using Cortexin for children with speech delay has not been scientifically proven. In the reviews of doctors, this is confirmed.
This happens because in different situations with pathologies of the nervous system and the brain, its effect may be different. In some children, a positive effect is noted already at the beginning of therapy with the drug, in others it can be almost invisible. Nevertheless, pediatricians continue to widely prescribe this medicine, but at the same time they are trying to supplement this treatment with other medications.
Reviews about "Cortexin" for children
There are many positive reviews about the treatment of children with Cortexin medication, in which parents note that after a course of therapy, children begin to talk better, easily memorize poems, new information, become less nervous, and expand their vocabulary. In very young children, the drug accelerates the development of fine motor skills. According to parents, children learn to sit faster, roll on their tummy, get up, learn crawling, walking and so on. With a speech delay when the child is 3 years old, Cortexin, according to reviews, also helps a lot.
When treating school-age children, parents confirm the positive effect of the drug on thinking, memory and concentration. The medicine effectively helps patients of this age group of children with difficulties with the assimilation of educational material, low learning ability, and problems with speech. At the same time, experts also emphasize that injections help eliminate the detrimental effects on the brain of hypoxia, stress, trauma and other negative factors. However, many doctors attribute the medication and other nootropics to the group of medicines whose effectiveness has not yet been proven.
"Cortexin" for a child’s speech, according to reviews, is well tolerated. Local reactions to the drug are extremely rare and, most often, this occurs when it is diluted with novocaine.
There are also some negative reviews about this medication, in which parents complain about the high cost of the drug for one course of treatment and the pain of injections. In some children, there was a lack of a positive effect on the activity of the nervous system. In addition, many parents are not satisfied with the fact that this medical product is released only in injectable form, as a result of which they choose an analog drug in tablets or syrups.
According to doctors, Cortexin is very suitable for children. It is well tolerated, rarely causes side effects.
We reviewed the instructions and reviews for the Cortexin drug for children.