Amiksin is a medicine made on the basis of tilorone. The drug belongs to the class of antiviral. This is an immunomodulatory agent. As you can conclude from the reviews about it, the drug is quite effective, although in some cases the persons who used it were categorically dissatisfied with the result. Consider the features of the drug and its administration, as well as responses about it.
What are people talking about?
As you can conclude from the reviews, the instructions for use of Amiksin have an extensive list of indications, but it does not help everyone. Some individuals noted that the tool quickly and reliably helped, while others recognized that there was no effect from its use. If you study the responses in special publications devoted to the aggregation of user opinions, you can find out that some of hers got herpes worsened while taking the drug, while others, using such pills, quickly treated the manifestations of a chronic disease.
How effective will be the treatment of many diseases that Amixin treats, according to the instructions, from the reviews is not always clear, but the responses are more positive for those who use the drug under the supervision of a specialist. However, if opinions on the effectiveness of the remedy differ, then the responses devoted to its cost are quite similar: the majority admits that the medicine is very expensive. A pack of medication for children costs from 700 rubles, for adults - even more expensive.
general information
The instruction for Amixin tablets indicates the presence of tilorone, which is included in the product as the main ingredient. The drug is made in the form of tablets with a thin shell. If you break the pill, you can see the orange filling. White inclusions are possible. One tablet contains 60-125 mg of the active ingredient.
Additional components are starch, cellulose, calcium and sodium compounds, povidone. For the manufacture of the shell, polysorbate, coloring ingredients, sykovit, macrogol, hypromellose, titanium dioxide were used. As you can see, the composition of the tool is quite simple and transparent.
Pharmacology
Characterized by such diverse reviews of use, Amiksin is an antiviral drug that belongs to the group of inducing the production of interferon.
This is a low molecular weight substance, made in vitro artificially. Under its influence, the generation of three types of interferon is activated in the body. Mostly, the agent affects intestinal epithelial cells, granulo-, lympho-, hepatocytes and neutrophils capable of producing interferon. After ingestion, the maximum activation of interferon production is observed first in the intestinal tract, then in the liver, and then in the blood. For the first results, it takes about 4 hours, the maximum effect is not achieved immediately, but takes about a day. An antiviral effect is observed due to the immunomodulating properties of the drug.
Containing the active ingredient in an amount of 60 mg to 125 Amixin, it is able to activate the synthesis of interferon. It affects stem marrow cells. The effect is dose dependent. It is possible to increase the generation of antibodies, reduce the suppression of immunity, restore compliance with helpers, type T suppressors. There is effectiveness in viral invasion, including influenza, herpetic viruses, hepatitis. The mechanism of the fight against viruses is due to inhibition of translation of specialized viral proteins. Due to this feature, the reproductive ability of the virus decreases.
Kinetics
For children and adults, the instructions for use of Amiksin in tablets indicate the ability of the drug to be absorbed in a short time when passing through the digestive tract. Bioavailability is estimated at approximately 60%. The ability to enter into strong bonds with plasma proteins is estimated at 80%.
The main ingredient of the drug is not subject to biological transformation reactions when in the human body. It does not have a cumulative effect. Mostly elimination occurs in its original form. The main percentage is excreted in the intestinal tract with feces. About 9% are eliminated by urine. The elimination half-life averages 48 hours.
When will it help?
Adult instructions for use "Amiksin" is recommended as a prophylactic that eliminates the flu, SARS. You can use a pharmaceutical product in the complex treatment of pulmonary tuberculosis, chlamydia (respiratory and affecting the urogenital tract). The drug treats viral hepatitis, herpes, cytomegalovirus. The pharmaceutical product is effective as an element of a combination program when it is necessary to treat encephalomyelitis due to allergies or due to viral invasion. It is allowed to include drugs in the program to combat uveo-, leukoencephalitis, multiple sclerosis.
For children over the age of seven, the pills in question are prescribed if the child is sick with SARS or the flu.
Hepatitis treatment
The medication is intended for oral use. The drug is taken before a meal. Adult instructions for the use of Amiksin, if necessary, a nonspecific preventive measure recommended a six-week course (if you suspect hepatitis A). The tool is used once a week, taking 125 mg. In total, the patient receives 0.75 g of the drug per course. In the fight against hepatitis of this type, 125 mg is taken twice on the first day, then the same dose is used every two days. In total, a dozen tablets are indicated for the course.
If the examination showed hepatitis B, which is just beginning, the course is acute, 125 mg should be taken in the first two days, then switch to taking the drug once every two days. In total, a person should receive 16 tablets for the program. With prolonged development of the disease, on the first day, take 125 mg twice, then switch to once every two days. In total, two dozen capsules are received for the duration of treatment.
In chronic hepatitis B, it is shown at first to take 20 tablets. In the first two days, they consume 250 mg of the drug, then they start to drink the drug once every two days. After completing the initial stage, go to the second step: 10-20 tablets are taken, consuming 125 mg once a week. In total, the patient will receive 3.75-5 g of the drug per course. The duration of therapy varies from 3.5 months to six months. The specific duration is determined by biochemical characteristics, immunology, the results of morphological analyzes showing how actively the treatment is proceeding.
Hepatitis C
Instructions for the use of Amixin tablets for hepatitis C in case of acute course are indicated in the first two days, 1 unit per day. Then take a tablet every two days. The course is 20 tablets.
In the chronic course of the disease, a course of 20 tablets is first required. In the first two days, the patient receives two tablets, then appoint a tablet every two days. The second stage of treatment - 20 tablets, used 1 piece per week. In total, the patient receives 40 tablets (or 5 g of the drug) for the course. The duration of therapy is six months. Biochemistry, morphology, and the state of immunity are regularly checked to correct the therapeutic program.
Neuroviruses
Amiksin is a drug that is effective in the fight against neuroviral infection. With this diagnosis, the drug is used as an element of a comprehensive treatment. In the first two days, the patient is shown to take a tablet or two. Then - 1 dose every two days. Duration usually varies within four weeks.
In the fight against acute respiratory viral infections, influenza in the first two days should receive a tablet per day, then the frequency is halved. In total, six tablets are shown to a person during treatment.
Cytomegalovirus and other viruses
Infection with cytomegalovirus or herpes requires the use of a capsule of the drug in the first two days, then halve the frequency. In total, during the treatment period, the patient should take from a dozen tablets.
Amiksin is a medication effective in chlamydia. In the first two days it is shown to take a tablet, then use a capsule once every two days. In total, a dozen tablets should be taken during the treatment period.
With pulmonary tuberculosis in the first two days, the patient receives 250 mg per day, then the program is changed using a tablet for two days. In total, during the treatment, the patient receives two dozen tablets.
What about the children?
Amiksin is a medicine approved for use by children over the age of seven. If the child is sick with SARS, the flu, the disease flows without complications, it is indicated to take a tablet containing 60 mg of the active component. Take after a meal in the first two days of illness, then another day later. In total, the child receives three capsules. In severe cases of the disease, the drug is used for the first two days, then twice more every other day. In total, the patient receives four capsules per course, which is 0.24 g of the active ingredient. If necessary, taking the drug is allowed for young children, but older than 1 year.
Unwanted effects
The use of Amiksin tablets can provoke dyspeptic symptoms. Cases of short chills are known. Allergic reactions to the components of the drug are recorded. But often the medication is well tolerated by patients. Most, as official studies show, have no side effects. But if you turn to reviews about the use of a pharmaceutical product, you can see that some have encountered undesirable effects, noted the lack of effectiveness of the drug. To minimize the risk of side effects, you need to consult a doctor before starting the course.
Sometimes you can’t
Contraindication to the appointment of the drug is intolerance to any substance used by the manufacturer of the drug. Possible high sensitivity of the body to the components of the drug. The drug is not intended for children under the age of seven without a doctor's prescription. The drug is not prescribed for pregnant women and is not used during lactation.
About the nuances
The use of Amiksin in combination with antibiotics is allowed. The drug can be combined with other drugs used to combat bacterial invasion or when a viral agent penetrates.
There have been no cases of overdose. According to doctors, the drug is compatible with drugs from other pharmacological groups, and their administration cannot be a contraindication to the use of Amiksin.
Possible alternatives: Tamiflu
The need for selection of replacement arises if, for some reason, the drug prescribed by the doctor did not fit. The fact that such cases do occur can be found by reading the reviews on the use of Amiksin by some children and adults. The instructions say that this medicine is antiviral. If you study the pharmacy assortment for the availability of antiviral medications, as well as get opinions on different products, you can conclude: one of the reliable options is Tamiflu capsules.
This medicine is in the form of hard capsules. The case is gray, the cover is painted yellow. Inside the capsule is a powder of white or yellowish tint. The main ingredient is oseltamivir. The capsule contains 75 mg of this substance. As additional ingredients, starch, povidone, mellose, talc, stearyl fumarate are included. For the manufacture of the shell used gelatin, coloring components, titanium compounds. It is especially important to become familiar with the complete list if a person is allergic to substances used in the pharmaceutical industry. For example, the product does not contain lactose, which many people today have intolerance to. Gluten free ingredients are also not listed.
How it works?
Tamiflu is an antiviral medicine. It effectively inhibits viral neuraminidase, that is, an enzyme that activates the release of young virus particles from an infected cell. In laboratory conditions, the ability of the drug to slow down viral development has been proven. The concentration that allows to inhibit neuraminidase in half corresponds to 0.1-1.3 nM for A-flu, 2.6 nM for B-virus.
We conducted tests that proved that the drug does not correct the activity of producing antibodies to influenza. The drug does not affect the generation of antibodies if the patient receives a vaccine against this disease. Studies were conducted during the flu epidemic. Individuals received capsules of the drug in the first 40 hours after the onset of symptoms. In the majority, virus A was detected, virus 3 was detected in 3%. In both cases, taking the medicine reduced the duration of unwanted symptoms by an average of 32 hours.
How to use?
"Tamiflu" is shown de older than 1 year and adults for the treatment of influenza. It is used to prevent this disease in people under the age of twelve, if the probability of infection is estimated to be above average. It is allowed to use Tamiflu as a prophylactic if there is a danger of contracting the flu.
The drug is used orally. It is recommended to receive the remedy with a meal or immediately after eating. In general, the drug is absorbed, tolerated better if taken with food. If a person cannot swallow a capsule, use powder. As such, use the contents of the capsule, opening it. It is allowed to open the capsule if it has become brittle due to prolonged storage. The drug is combined with a small spoon of sweetened food (syrup, honey), thoroughly mixed and given to the patient. Once the drug is prepared, you must immediately take it. Store the prepared mixture is strictly prohibited.
It is advisable to begin treatment in the first two days of the onset of symptoms of the disease. People over the age of twelve are shown to receive 75 mg twice a day. The duration of the course is five days. Increasing the dosage will not make the effect stronger.
These two drugs are quite effective and help to cope with respiratory diseases and flu in a fairly short time. Especially in the winter when viruses "wake up".