What is Pramistar? Instructions, reviews about this medicine will be described below. We will also tell you about the properties of this medication, for what purposes it is prescribed, whether it has adverse reactions and contraindications.
Composition, description, form
What packaging is Pramistar sold in? Tablets (reviews about this medicine are ambiguous) are placed in contour packs that are contained in cardboard boxes.
The active substance of the drug is pramiracetam. The composition also includes auxiliary ingredients in the form of polyethylene glycol, colloidal anhydrous silicon dioxide, crospovidone, calcium stearate, hydroxypropyl cellulose, titanium dioxide, polyethylene glycol, microcrystalline cellulose and hypromellose.
The tablets are coated, have a white color and an elongated shape with a risk.
Pharmacodynamics of the drug
How does the Pramistar medication work? Reviews of doctors say that the active component of this agent belongs to nootropics, pyrrolidine derivatives and racemates. The drug improves memory, activates the processes of motivation and promotes learning.
The principle of action of this medicine is not fully understood. However, experts argue that this medication is able to activate high affinity uptake and neuronal activity of choline in the cholinergic parts of the brain.
It should also be noted that the drug in question is actively involved in the synthesis of phosphatidylcholine. It restores the structure of the membranes of neurocytes and improves their plasticity.
How is the effect of the Pramistar medication manifested? Patient reviews indicate that this remedy does not have a sedative effect, but at the same time it directly affects the central and autonomic nervous systems.
The active substance of the drug increases the time during which people can concentrate on something. Also, the medication improves memory and activates mental work.
After taking the tablets, the structure of the reticular formation is restored , and the microcirculation of brain tissues is normalized.
Experts believe that this drug is very effective as an antidepressant.
Pharmacokinetics of oral medication
Is the drug “Pramistar” absorbed? Reviews say that after taking the tablets, their active component is rapidly and completely absorbed into the bloodstream. The highest content of pramiracetam in the blood is observed after two hours. Its half-life is six hours.
The drug is not metabolized in the liver and does not bind to plasma proteins. It is excreted unchanged along with urine.
Indications for use of Nootropic
Why can Pramistar be prescribed? Reviews say that such a tool is actively used for:
- senile dementia;
- discirculatory encephalopathy;
- memory impairment;
- emotional lability.
It should also be noted that this medication can be used during the recovery period after a head injury and ischemic stroke, in older people to improve the processes of thinking and remembering, to increase motivation, concentration, and interest in life, to eliminate irritability, melancholy and various cognitive disorders .
Contraindications
Under what conditions can not be prescribed "Pramistar" (tablets)? Instructions, reviews indicate the following contraindications:
- pregnancy and breastfeeding;
- cerebral hemorrhage;
- allergy to drug substances;
- severe liver or kidney disease.
The drug "Pramistar": instructions for use
You can find reviews on the effectiveness of pills at the very end of the article.
According to the attached instructions, the product in question should be swallowed whole. To achieve the desired result, the medicine must be taken for at least a month. As a rule, the course of therapy is sixty days.
The drug "Pramistar" is prescribed one tablet twice a day. Dose adjustment for elderly patients is not required.
People with kidney disease should monitor their work during the entire course of treatment. If in the process of this there are any undesirable effects, then therapy should be discontinued.
Cases of overdose
To date, there have been no cases of overdose of the drug in question. If the recommended doses have been exceeded, then gastric lavage should be performed, as well as enterosorbents.
Side effects
Does the drug “Pramistar” cause undesirable reactions? Reviews say that side effects of this drug are extremely rare.
In some cases, the following phenomena are possible:
- dizziness, severe agitation, headaches, tremors;
- indigestion, dry mouth, pain in the abdomen, nausea;
- insomnia, dysphoria, urinary incontinence, confusion;
- anorexia, fecal incontinence, cramping.
Drug interaction
Before using this drug, you should definitely learn about its drug interaction. According to the instructions, it is not recommended to be taken simultaneously with Captopril, Digoxin, Warfarin and Theophylline.
The drug "Pramistar" is able to reduce platelet aggregation processes. In this regard, it should not be combined with anticoagulants and platelet aggregation inhibitors .
Side effects such as irritability, insomnia or confusion are aggravated with the simultaneous administration of Thyroxin and Triiodothyronine, as well as with other thyroid hormones.
Special recommendations
The use of the drug in patients with renal failure should be accompanied by strict monitoring of the kidneys.
If the patient has such side effects as confusion, tremors and dizziness, then driving is not recommended.
Synonyms, prices and analogues of a medicinal product
A synonym for this tool is the drug "Pramiracetam". There are also a number of analogues that have a similar mechanism of action. These include the following medications: Picamilon, Aminalon, Lira, Biotropil, Glycine, Vasavital, Bifren, Visebrol, Encephabol, Gamalate B6, Cerebrolysin ”,“ Dendricks ”,“ Phenotropil ”,“ Cavinton ”,“ Phenibut ”,“ Calcium Gopantenat ”,“ Fezam ”,“ Vinpotropil ”,“ Pantogam ”,“ Noben ”,“ Piracetam ”,“ Tiocetam ”,“ Omaron ” , “Cogitum”, Noofen, “Noopept”, “Nootropil”, “Neuro-Norm”, “Ceraxon”, “Neyrovin”, “Cognum”, “Quattrex”.
To purchase this drug in the territory of the Russian Federation is quite problematic. Therefore, most patients order it from online pharmacies. It should be noted that the cost of this medicine is very high and amounts to 1500-2500 rubles.
The drug "Pramistar": reviews of the effect
Despite the fact that acquiring a nootropic drug in conventional pharmacies is problematic, there are quite a lot of reviews about it. It should be noted that they are ambiguous.
Most patients who have been prescribed this medication report that the Pramistar medicine significantly increases and improves memory, as well as stimulates the processes of thinking and awakens motivation for active activity.
Some people who have completed the full course of treatment claim that after taking the pills they became “completely different.”
As for the negative reviews, that most often they are associated with the development of adverse reactions. Of the side effects, nausea and drowsiness can be highlighted. By the way, drowsiness is very pronounced in the first few weeks of treatment. It should be noted that almost all patients get enough sleep better. They dream only memorable and vivid dreams.
In addition to improving memory and mental activity, this tool turned out to be quite effective in the treatment of traumatic brain injuries, as well as in the restoration of cognitive abilities in the elderly.
According to patient reviews, this drug significantly improves learning abilities. Thanks to him, you can pass exams well. Although some young people claim that after a month's course, this drug causes obsessions. At the same time, its abrupt cancellation leads to drowsiness and lethargy.
Most people who use or want to use this tool are confused by its price. Compared to other drugs of similar action, Pramistar is very expensive. Moreover, it is difficult to access.
As for the reviews of specialists, they report that this drug should be taken only after consulting a doctor, as well as under his strict control. It is also necessary to keep in mind that the medication under consideration is intended only for the treatment of serious disorders in the central nervous system. Use of it at your own discretion is prohibited. Otherwise, this can adversely affect the patient’s health and his overall emotional state.