Afobazol is a modern over-the-counter drug produced in Russia, capable of combating anxiety disorders in adults. Afobazole acts as a light tranquilizer and is widely used in general practice. The drug has proven itself due to its good tolerance and effectiveness.
Description of the drug "Afobazol"
A synthetic drug related to anxiolytics. Afobazole acts as an anti-anxiety agent without interacting with benzodiazepine receptors, without giving a sedation effect. The drug activates the nervous system, removing asthenia, fatigue and anxiety. Does not relax muscles, does not dull attention, does not impair memory. The drug does not develop dependence and withdrawal syndrome upon discontinuation of administration. With a calming effect, Afobazole indirectly improves sleep, accelerating the process of falling asleep. Corrects vegetative symptoms and mood swings.
Suction and removal
The drug is taken orally and reaches a maximum concentration, absorbed from the stomach in less than an hour. The conversion of the active substance is in the liver. It is excreted quickly, holding in the blood for a maximum of two and a half hours. A medicine has the property of increasing its concentration in organs that have the most developed blood supply, including in the brain, quickly passing into the smallest vessels and capillaries. Excretion is carried out with urine and feces in the form of metabolically altered compounds.
How long does Afobazole work? For a positive anti-anxiety effect, the drug should accumulate within a week, and the maximum benefit is achieved only after four weeks of regular administration of the drug.
From what tablets "Afobazol"
The drug is used in the treatment and correction of the following conditions in adults:
- It is used for generalized anxiety disorders, accompanied by constant underlying anxiety, which can occur on the slightest occasions and without them.
- The use of the drug makes sense with agoraphobia, when patients cannot leave their homes and be in public places without fear and somatic symptoms.
- Afobazole is prescribed for panic attacks that haunt a person in the form of anxiety attacks with fear of death and autonomic reactions that occur for no apparent reason.
- With neurasthenia has a good effect due to a mild activating effect.
- In adaptation disorders, Afobazole acts as an anxiolytic and mood stabilizer.
- With somatoform autonomic dysfunction, manifested by various bodily manifestations without damage to organs or systems of the body.
- In the complex treatment of psychosomatoses (bronchial asthma, hypertension, peptic ulcer, atopic dermatitis, rheumatoid arthritis, hyperthyroidism) Afobazole acts as a tool that positively affects the nervous system by calming. Thus, it stabilizes the condition of the affected organs.
- To complement the treatment of insomnia, accompanying neurotic disorders, as well as arising independently.
- Gynecologists use the drug to relieve symptoms in the premenstrual period, as well as to reduce pathological climacteric manifestations (irritability, headaches, sweating, anxiety, mood swings).
- By narcologists and toxicologists, the drug is prescribed to alleviate withdrawal symptoms when giving up alcohol after prolonged systematic use, as well as to improve the state of craving for smoking when trying to quit addiction.
- Doctors of all profiles use the medication widely to stabilize the state of the nervous system in chronically ill patients, including those with cancer, cardiac pathology, and skin manifestations.
Mode of application
Knowing why Afobazol tablets are prescribed in general practice, you need to understand the dosage regimen and duration of use of this drug.
The drug is prescribed only to adults after eating orally. The medicine is taken one tablet three times a day with an average daily dose of 30 mg. Under the supervision of a doctor, it is possible to increase the dosage to 60 mg per day. Most often, this occurs in the regimen of two tablets three times during the day.
The average course of Afobazole is from two to four weeks. With long-term treatment of nervous system disorders, the use of this drug may be longer, up to three months.
When prescribing and taking a medication, it should be remembered that it tends to accumulate in the body for at least a week, and the anti-anxiety effect fully unfolds by the end of the month of administration, remaining in the body even after stopping the use of the drug for about two weeks.
Contraindications
Soothing tablets "Afobazole" can not be taken with:
- Pregnancy
- Breastfeeding.
- In children under 18 years of age.
- Individual hypersensitivity reactions to the main or auxiliary components of the drug, including lactose intolerance.
Side effects and overdose
The drug is very well tolerated.
Of the undesirable effects, the occurrence of allergic manifestations in the form of skin rashes, itching of the skin, Quincke's edema can be noted. Very rarely, patients are bothered by a headache associated with taking Afobazole.
Taking the medication in dosages that significantly exceed the average recommended doses can cause overdose symptoms. They manifest themselves in severe drowsiness without muscle relaxation. To remove this undesirable effect, a 20% solution of caffeine-sodium benzoate-sodium should be administered subcutaneously one milliliter up to three times.
special instructions
The medicinal substance is not used in childhood.
Pregnant and lactating women should not use this tool.
Drivers and workers involved at heights and other hazardous types of work can use Afobazole in the recommended dosages, since the drug has no effect that can slow down the reaction and reduce the concentration ability of a person.
Interactions with Other Medicines
Consider how the drug manifests itself while taking it with other drugs:
- Afobazole does not react with ethyl alcohol.
- Hypnosis Medication “Tiopental” does not reduce its effect when taking “Afobazole”.
- When used together with "carbamazepine" and its analogues, the anticonvulsant effect increases.
- The anxiolytic "Diazepam" begins to act with great effect.
Reviews
When studying the drug "Afobazole" with instructions for use and price, reviews of this drug from doctors and patients also deserve attention.
Psychiatrists, psychotherapists and narcologists note the medication in most cases on the positive side due to the stable anti-anxiety effect and good tolerance. In this case, a rule applies that says not to harm the patient. Therefore, doctors clearly distinguish between conditions in which it is advisable to prescribe this drug, and in which it will no longer be effective and valuable time will be lost.
When doctors appoint Afobazole for neurotic disorders, the degree of impairment of the nervous system, the duration of the disease, and what medicines the patient has taken before, which helped and worsened well-being, are taken into account. It should be remembered that when self-medicating in cases of pathology affecting the brain and peripheral nervous system, you can seriously harm yourself, so all drugs should be prescribed only by a specialist.
Patients who took Afobazole in medium therapeutic dosages, doing this regularly, without missing a dose and during the period prescribed by the doctor, characterize this medication as an effective way to combat anxiety as the main manifestation of neurosis. After examining the statistics on sites with drug reviews, you can present the result as a percentage of positive responses, which according to various sources ranges from 74 to 100%.
The form of release, storage, dispensing of the drug and the price in pharmacies
The drug substance is compressed into 10 mg white tablets with the addition of potato starch, cellulose, lactose, magnesium stearate and povidone.
Tablets are packed in blisters of 20 units, which are three pieces are packed in a cardboard box.
Keep the medicine where children can not reach it. Storage temperature should not exceed 25 degrees, avoiding direct sunlight and high humidity. Shelf life of the drug is three years from the date of manufacture, it is prohibited to use the product after this period.
The medicine can be bought in the pharmacy network without a prescription form. Instructions for use are attached to each package.
In reviews of Afobazole, the price of this drug is described as acceptable. The cost of pharmacies varies from 326 to 535 rubles.