In the article, we consider the instructions for use, price and reviews for Ginoflor candles.
The medical product is a local medicine, designed to normalize the microflora in the vagina in women.
This pharmacological agent is produced in tablet form for intravaginal administration, 6 pieces in blisters packaged in cardboard boxes, one or two blisters. One vaginal tablet of the drug contains 50 mg of the active ingredient - acidophilic lactobacilli lyophysylate, as well as additional substances - lactose and estriol.
Pharmacological action of the drug
According to the instructions, Ginoflor suppositories are intended for vaginal use. The main active substance of the drug helps to restore the correct balance of microflora in the vagina and inhibit the growth of pathogenic microbes and yeast-like fungi.
Estriol, which is also present in the composition of tablets, is a specific synthetic compound, which is identical in therapeutic effect to hormones produced by the ovaries of healthy women. Estriol has a therapeutic effect exclusively on the mucous membranes of the genital tract and does not contribute to impaired endometrial function. This medical product improves the protective properties of the mucous membrane and stimulates the reproduction and growth of the necessary lactobacilli.
Instructions for use for suppositories "Ginoflor" indicates that lactose, which is part of the tablets of this medicine, ensures the reproduction of lactobacilli in the vagina and the synthesis of lactic acid.
With intravaginal administration of the tablet, a gradual release of the basic elements occurs. The drug acts locally without being absorbed into the general bloodstream. The therapeutic effect is observed several hours after the use of the tablet.
So it is said in the instructions for use for candles "Ginoflor E".
Both active substances in the composition of the drug are involved in the physiological mechanisms of maintaining proper biocinosis in the vagina. The proliferating vaginal epithelium is able to accumulate glycogen in itself, which is necessary for the life of lactobacilli producing lactic acid, maintaining an acidic environment in the vagina. This creates negative conditions for the development and colonization of pathogenic microorganisms.
The price of Ginoflor E candles is not indicated in the instructions for use.
In addition to lactic acid, lactobacilli produce bacteriocins and hydrogen peroxide, which also inhibit the development of pathogenic bacteria. Violation of the physiological vaginal flora can occur due to various factors: systemic or local use of antibacterial drugs, including as a result of systemic pathologies, vaginal infections, and non-compliance with hygiene rules. In such cases, the number of lactobacilli can significantly decrease. Vaginal administration of the drug normalizes the structure of the vaginal epithelium and restores the microflora. This is confirmed by the instruction.
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The vaginal epithelium can be damaged and thinned also with hormonal changes in the body, and therefore this drug can be prescribed in postmenopausal women, weakening its local symptoms (burning, itching, dryness in the vagina, pain during intercourse) and helps normalize the structure of the urethral epithelium and vagina, reducing the incidence of degenerative conditions.
Indications for appointment
As the instruction for Ginoflor suppositories indicates, a vaginal medication is prescribed for women during therapy and prevention of the following pathological phenomena:
- during menopause in order to normalize microflora;
- with prolonged use of antibacterial drugs, as a result of which the normal environment in the vagina can be disturbed;
- with often recurring thrush;
- with atrophic vaginitis;
- with inflammatory processes of the vaginal mucosa, not complicated by infections;
- with vaginal dysbiosis, which may be accompanied by abundant secretions with an unpleasant odor.
Contraindications
According to the instructions for Ginoflor suppositories, before using this medication it is important to consult with your gynecologist and carefully read the annotation attached to the medication, as it has a number of limitations and contraindications for use:
- individual intolerance to the elements present in the composition of the product;
- age up to 18 years;
- a variety of bleeding of unknown etiology from the genital tract;
- the presence of malignant tumors of the cervix and vagina;
- uterine endometriosis;
- endometrial hyperplasia;
- treatment of a girl before sexual activity;
- tumor of the mammary glands of malignant origin.
Dosage regimen, method of use
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Ginoflor E medicine is intended exclusively for intravaginal use.
According to the annotation for the proper use of this medication, the tablet must be moistened well in running water, and then entered deep into the vagina. It is recommended to introduce one tablet per night. If during a therapeutic procedure a woman begins menstruating, then two days after its completion, it is necessary to continue therapy.
The duration of the treatment course is determined by specialists depending on individual characteristics and indications.
After chemotherapy or a long course of treatment with antibacterial drugs, a woman is usually prescribed 2 tablets of the drug once a day at night for seven days, after which the patient is recommended to switch to the standard dosage - 1 tablet once a day.
This describes in detail the instructions for the candles "Ginoflor".
Use during pregnancy and lactation
In the first trimester of pregnancy, this pharmacological drug should be used with some caution. In the subsequent periods of carrying a child to future mothers, “Ginoflor E” is prescribed according to indications in moderate dosages. Clinical studies have not determined the embryotoxic or other negative effects of the main and additional components of the drug on the fetus.
The use of a pharmacological agent during lactation is carried out exclusively according to the indications and in controlled dosages. The active elements of the drug do not penetrate into breast milk, since they are practically not absorbed into the systemic circulation.
Side effects
According to the instructions and reviews, Ginoflor E candles in most cases are well tolerated by patients. In cases of hypersensitivity in patients, certain local reactions may occur, which in some cases may occur in the following:
- discomfort in the vagina after intravaginal administration of the drug;
- itching or burning;
- redness of the mucous membranes of the genital tract.
The above symptoms, as a rule, are very slightly expressed and do not require the abolition of a medical device.
This tells us the instruction. According to reviews, the price of Ginoflor candles is quite acceptable.
No cases of drug overdose have been recorded in medical practice, however, in order to prevent the above side effects, it is not recommended to increase the dosages indicated in the instructions for the medicine.
Drug interaction
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With simultaneous therapy with a pharmacological agent with antibiotics or bacteriostatic medicines, a decrease in the therapeutic effectiveness of these tablets is observed. In addition, they are not recommended for use in concomitant treatment with other topical medicines, as this can significantly weaken the therapeutic effectiveness.
Instructions for candles "Ginoflor E" is very detailed.
Special recommendations
During the use of the vaginal product, it is recommended to avoid sexual contact, since the medicine can have a negative effect on the integrity of latex products, which must be warned about for patients who are not planning a pregnancy in the near future.
Storage conditions
The drug must be stored in a cool, dark place at a temperature not exceeding 8 degrees (in the refrigerator). Storage of the medicine at room temperature leads to the death of lactobacilli.
This is indicated in the instructions for use with Ginoflor candles.
Price
The approximate cost of these vaginal tablets is 950-1650 rubles, depending on how many tablets are contained in one in the package. It depends on the region and the pharmacy network.
Analogs
The following drugs are similar in therapeutic effect with the drug “Gynoflor E”:
- “Vagilak” is a medicine that helps to normalize the natural vaginal environment, maintaining acidity in the range from 3.7 to 4.6, and increases the resistance of the mucosa to the influence of pathogenic microflora. The medication helps to eliminate such symptoms of vaginal dysbiosis as burning and itching in the perineum, a feeling of discomfort, copious discharge with an unpleasant odor. This pharmacological agent helps to reduce the likelihood of relapse of the disease.
- "Ginolact" is a medicine, which contains lactic acid bacteria that act antagonistically against pathogenic strains of microorganisms. They provide the normalization of the natural mechanism of protection of the vaginal mucous membranes due to the conversion of glycogens to lactic acid, which reduces the level of acidity, which is unfavorable for the multiplication of streptococci, trichomonads, etc. This medication is able to quickly restore microflora.
- "Terzhinan" is a medicine of combined structure for local use in gynecology. It has an antiprotozoal, antimicrobial, antifungal and anti-inflammatory effect, ensures the integrity of the vaginal mucous membranes and stabilizes the pH. Ternidazole, as one of the main elements of the drug, reduces the production of ergosterol, changes the properties and structure of cell membranes, and has a trichomonacid effect. In addition, the drug contains neomycin, an antibiotic from the aminoglycoside category, which has a bactericidal effect on many pathological microorganisms, and nystatin, an antifungal antibiotic from the polyene category, which is highly effective against yeast-like fungi. Also, the composition of this medication contains prednisone, an analog of hydrocortisone, which has a pronounced anti-inflammatory, anti-exudative and anti-allergic effect.
- "Gentaxan" is a complex long-acting antimicrobial agent for topical application, which includes aminoglycoside sulfate, a compound of zinc and tryptophan and polymethylsiloxane in the composition of gentamicin. Gentamicin is an active element of the drug, which is a broad-spectrum antibiotic.
Another active substance - polymethylsiloxane - provides a sorption-detoxification effect and, together with zinc-tryptophan, has an antibacterial effect. Due to the sorption properties, this medicine absorbs toxins of pathogenic bacteria, low molecular weight metabolites and fibrin degradation products. The mechanism of action of the drug is associated with the prevention of protein production by microorganisms and with the violation of the bilipid layers of cell membranes. The medicine reduces the manifestation of general and local intoxication, normalizes gas exchange, microcirculation and pH.
Reviews
The problem of vaginal dysbiosis in recent years has been very acute in women of various ages, which may be due to adverse environmental conditions, poor nutrition, viral diseases and weakened immunity. Especially taking antibiotics greatly violates the microflora, which is expressed in unpleasant burning symptoms and severe itching in this area, and these phenomena, in turn, violate the woman’s lifestyle and mood.
The medication Ginoflor E is widely prescribed in clinical gynecology in case of the occurrence of “thrush” in women and other pathological conditions described above. The reviews of specialists contain information that this pharmacological agent is considered one of the most modern and effective in the domestic market of medicines, and, despite the high cost, is in great demand. It is prescribed to all women in case of unpleasant symptoms in the vagina for the treatment of microflora dysbiosis, as well as for preventive purposes during the use of antibacterial drugs.
Reviews of patients who used these vaginal tablets are, for the most part, positive. Women observed that with “thrush” the drug “Ginoflor E” gave a very quick therapeutic effect, and already on the first day of the acute condition the symptoms were significantly reduced - the itching in the vagina became less pronounced, the general condition also improved. There are no negative reviews about the Ginoflor medicine.
As for the negative side effects from the use of this medication, they are not described in the reviews, on the contrary - women observed the absence of such phenomena and very good tolerability of the medication.
We reviewed the Ginoflor E candles and instructions and reviews.