The drug "Sedalgin Plus" is a combination agent that has a pronounced
antipyretic, analgesic and anti-inflammatory effect. The basis of the action of this medicine is the inhibition of the growth and reproduction of prostaglandins by inhibiting the cyclooxygenase enzyme. The use of this anti-inflammatory drug can improve neuro-reflex conductivity, stimulate metabolism and increase the bioavailability of analgesics. The increase in the permeability of histohematological barriers and the consequent enhancement of the therapeutic effect is also provided by the Sedalgin Plus combination drug, the price of which varies from 90 to 170 rubles.
This analgesic is produced in the form of round tablets containing metamizole sodium, caffeine and thiamine hydrochloride as active components .
Auxiliary ingredients are substances such as
wheat starch and microcrystalline cellulose. Talc is also found in Sedalgin Plus. The composition of this tool is supplemented with a small amount of silicon dioxide, gelatin and magnesium stearate.
As for the scope of this anti-inflammatory drug, it is usually prescribed for the relief of moderate or mild pain syndrome of various origins. For example, to eliminate migraines. In case of neuralgia, the purpose of the combined drug "Sedalgin Plus" is also shown. In addition, this anesthetic drug is actively used for arthralgia - joint pain, myalgia - muscle pain, algodismenorrhea - menstrual pain, radicular syndrome. The fever, which often accompanies various colds and infectious inflammatory diseases, is also the reason for the appointment of these antipyretic tablets.
The main contraindications to the use of Sedalgin Plus are such conditions as renal failure, severe liver failure, individual intolerance to pyrazolone derivatives, hypersensitivity to metamizole sodium, caffeine and thiamine hydrochloride. In addition, you should not take this drug for people suffering from serious blood diseases, bronchospasm, hypertension, severe atherosclerosis, insomnia and increased intraocular pressure. The list of contraindications also includes pregnancy, lactation, age up to twelve years.
Using this drug, you must always remember the risk of unwanted side effects. For example, some patients complain of dizziness, loss of appetite, insomnia, vomiting, nausea, and increased heart rate. In addition, thrombocytopenia, cholestasis, hemolytic anemia, jaundice, purpura, Quincke's edema, leukopenia, anaphylactic shock and agranulocytosis may occur. If side effects occur, the drug should be discontinued.