The antiviral drug Cycloferon is a well-known Russian drug. The tool activates the resistance of the human body to various viral agents. The active component of Cycloferon is a high molecular weight substance that can enhance the synthesis of interferon in the body. A distinctive characteristic is the vastness of its pharmacological effects.
The composition of the drug "Cycloferon"
The active substance of this medication is meglumine acridone acetate, and water for injection is an auxiliary component. It is a clear liquid with a yellow color.
Also, the drug can be found in enteric-coated tablets. The active substance in the composition is also meglumine acridone acetate.
Pharmacodynamics
The drug "Cycloferon" acts as a low molecular weight inducer of interferon, which guarantees a very wide range of its immunomodulating, antiviral and anti-inflammatory activity.
The main producers of interferon after the introduction of Cycloferon are macrophages and lymphocytes. Depending on the type of infection, the prevalence of a particular link in the immune system is noted. This drug induces high titers of interferon in organs that contain lymphoid elements (we are talking about the spleen, liver, lungs). The medicine activates brain stem cells, and in addition, the formation of granulocytes is stimulated. Cycloferon activates lymphocytes along with natural killer cells, normalizing the balance between t-helpers and t-suppressors. Among other things, the activity of Ξ±-interferons is enhanced.
The antiviral drug Cycloferon is effective against viruses in pathologies such as tick-borne encephalitis, influenza, hepatitis, herpes, cytomegalovirus, immunodeficiency and others. In the presence of acute viral hepatitis, Cycloferon prevents the pathology from transitioning to the chronic stage. At the stage of the initial manifestation of HIV infection, this medicine helps to stabilize the immune parameters.
The great effectiveness of this drug in the complex treatment of acute and chronic bacterial infections (that is, with neuroinfections, chlamydia, bronchitis, pneumonia, postoperative complications, urogenital infections, peptic ulcers) as part of immunotherapy has been established.
The medicine "Cycloferon" is highly effective in rheumatic and systemic diseases of the connective tissue, it suppresses the autoimmune reaction and has an anti-inflammatory and analgesic effect.
Pharmacokinetics
When you enter the maximum allowable doses, the maximum concentration in the blood, as a rule, is achieved after two hours. After a day, the antiviral drug Cycloferon is already detected in trace amounts. The medicine is able to cross the blood-brain barrier. The withdrawal period is usually from four to five hours. It does not accumulate in the human body with prolonged use.
Indications for use for adults and children
The antiviral drug Cycloferon is used to treat adults as part of complex therapy:
- With HIV infection.
- Against the background of neuroinfections with serous meningitis and encephalitis and tick-borne borreliosis.
- If the patient has viral hepatitis.
- In case of herpes or cytomegalovirus infection.
- Against the background of secondary immunodeficiency associated with acute and chronic bacterial and fungal infections.
- With chlamydial infections.
What else does Cycloferon help from? It is used against the background of rheumatic and systemic pathologies of connective tissues (with rheumatoid arthritis, systemic lupus erythematosus, and so on), as well as in the presence of degenerative and dystrophic diseases of the joints. In this case we are talking about deforming osteoarthrosis.
For the treatment of children, Cycloferon is used as part of complex therapy:
- He is treating viral hepatitis in children.
- Therapy of herpetic infections.
- Treatment of HIV infection in children.
Contraindications
From what "Cycloferon" helps, we now know. Contraindications are pregnancy along with the period of feeding, hypersensitivity to the components of the drug, decompensated cirrhosis of the liver and children under four years of age.
Method of use in adults
So, how to take Cycloferon?
The medicine is usually used intramuscularly or intravenously once a day according to the basic therapeutic scheme: every other day. The duration of the treatment course depends on the disease:
- In the presence of herpes and cytomegalovirus infection, this medication is administered according to the basic scheme: ten injections of 0.25 grams. The total dose is 2.5 grams. Treatment is especially effective at the onset of exacerbation of the disease.
- With neuroinfection, the drug is administered according to the basic scheme. The course of therapy is twelve injections of 0.25 grams in combination with etiotropic treatment. The total dose is 3 grams. Repeated courses are conducted as required.
- With chlamydial infections, the drug is administered according to the basic scheme. The course of therapy is ten injections of 0.25 grams. The total dose is 2.5 grams. A second course of therapy is carried out after fourteen days. It is advisable to combine Cycloferon with antibiotics.
- In acute viral hepatitis and mixed forms, this drug is administered according to the following scheme: ten injections of 0.5 grams. The total dosage is 5.0 grams. With a prolonged course of infection, the course is repeated ten days later. In chronic hepatitis, the drug is administered according to the basic therapeutic regimen of 0.5 grams. Then, a maintenance regimen is carried out three times a week for three months as part of a complex treatment. This drug is recommended in combination with chemotherapy and interferons. The course is repeated after fourteen days.
- How to take Cycloferon in the presence of HIV? The drug is administered according to the basic scheme: ten injections of 0.5 grams. And then according to the supportive treatment plan: every three days for two months. The course is repeated after ten days.
- With immunodeficiency, a basic course is carried out. The total dosage is 2.5 grams. A second treatment course is carried out after twelve months.
- With rheumatic and systemic connective tissue disease, four courses of five injections of 0.25 grams each are taken with an interval of ten days. A second course is carried out on the recommendation of a doctor.
- In degenerative and degenerative joint diseases, two courses of five injections of 0.25 grams each are performed according to the therapeutic basic scheme with a break of ten days. A second treatment course is carried out on the recommendation of a doctor.
Instruction for children
The drug "Cycloferon" for children is used intramuscularly or intravenously once a day every other day. The daily therapeutic dosage is 10 mg per kilogram of weight.
- In the presence of acute viral hepatitis and against the background of mixed forms, this drug is administered according to the basic scheme, with fifteen injections being performed. In the presence of a protracted course of infection, the course is repeated after ten days.
- If the child has chronic hepatitis, the drug is administered according to the basic scheme, that is, ten injections are made. And then supportive treatment is undertaken three times a week for three months as part of a comprehensive treatment. This is confirmed by the instructions for Cycloferon for children.
- In the presence of HIV infection, a course of ten injections is carried out according to the basic treatment regimen. Then, supportive treatment is undertaken every three days for several months. A second treatment course is carried out in ten days.
- With herpetic infections, a course of ten injections is carried out according to the basic scheme. If the virus remains active, the Cycloferon therapeutic course for children according to the instructions is continued according to the maintenance schedule.
Dosage and administration of tablets
Pills are taken orally, half an hour before a meal, 1 time per day. They should not be chewed, but rather washed down with water.
Age dosages: for children from 4 to 6 years - 150 mg; from 7 to 11 years - 300-450 mg; adults and children from 12 years old - 450-600 mg. If necessary, repeat the course, but not earlier than after 2-3 weeks.
Side effect
Against the background of the use of this medication, patients may only experience allergic reactions. If any other side effects from Cycloferon are observed that are exacerbated, then they must be reported to the doctor.
Interaction with other medicines
The drug "Cycloferon" is compatible and combines perfectly with all medical devices that are traditionally used in the treatment of these diseases. This medication enhances the effect of interferons, and in addition, nucleoside analogues. Possible reduction in side effects of chemotherapy.
How much is Cycloferon, consider below.
special instructions
The medicine does not affect the ability to operate the machine. For diseases of the thyroid gland, consultation with an endocrinologist is required. Blue staining of urine is possible.
Release format
The solution is intended for intravenous, and in addition, for intramuscular administration. Five ampoules are placed in blister packs of polyvinyl chloride film. Another dosage form is tablets.
Storage conditions
This drug must be kept in a dark place at a temperature of up to twenty degrees. Freezing the solution during transportation at a negative temperature does not lead to a change in the properties of the drug. Thawed in the presence of room temperature, the drug can retain its biological and, at the same time, chemical properties. With a change in the color of the solution and the appearance of sediment, the use of this drug is unacceptable. Keep the medicine out of the reach of children.
Medication price
How much is Cycloferon, interesting to many. The tool in question will cost consumers 400 rubles. It depends on the region and the pharmacy network.
Analogs
The following medicines should be attributed to analogues:
- The drug βViferonβ costs two hundred rubles and is the cheapest type of immunostimulating medicine. This analogue is characterized by a sufficiently large antiviral activity.
- The medicine "Genferon" will cost three hundred rubles. It is released in the form of suppositories or spray. Applied with inflammatory pathologies of the urogenital tract. This is an antimicrobial immunomodulating drug of systemic and local action.
- Means "Interferon" costs one hundred and fifty rubles. It is released in ampoules for the manufacture of a solution. Indications for its use are the prevention and treatment of influenza or otolaryngological diseases, and in addition, hepatitis B and C. It is also used to treat genital warts, leukemia, myeloma, AIDS (if it is an uncomplicated acute infection), as well as in the presence of malignant melanoma.
The analogue of Cycloferon in tablets is Anaferon.
Reviews
In the reviews about this medicine, consumers mostly write positive comments. Reportedly, the medical tool Cycloferon is today one of the most reliable and proven drugs to maintain immunity.
To the positive aspects of the medication in question, people attribute the fact that it does not cause adverse reactions. In particular, this drug is praised by parents, whom he helped more than once in the treatment and prevention in children of various viral infections and otolaryngological diseases.
We examined the Cycloferon medication for instructions for use and reviews.