According to the instructions, "Dioxidin" (ointment, solution for topical application and injection into a vein) is an antimicrobial drug. It has an extensive range of efficiencies. "Dioxidin" is prescribed for infectious diseases provoked by the usual proteins, Klebsiella, intestinal and Pseudomonas regiments, as well as staphylococci, streptococci, salmonella, anaerobic life forms. The drug is effective against life forms that provoke gas gangrene.
When will it help?
From the instructions and reviews about "Dioxidine" it follows that the drug is effective in foci of inflammation, which are characterized by the generation of purulent mass. Doctors and people who have used the drug equally agree that Dioxidine has a pronounced effect. The medication is strong, effective, helps with inflammatory processes in different parts of the body. Based on localization, choose the optimal form of release - inject the drug into the circulatory system or apply externally.
The instructions for the use of "Dioxidine" (ointments and solutions) indicate the effectiveness of the composition with purulent purulent type, pulmonary abscess, inflammatory processes in the urinary system. The drug is used for phlegmon, peritonitis, pleural empyema, an abscess localized in soft tissues. Clinical practice shows the effectiveness of “Dioxidine” in the treatment of wounds received during the operation, as well as deep-cavity injuries. The appointment of the drug in question as a prophylactic after catheterization of the urinary system has shown effectiveness.
Dosing Nuances
In the instructions for "Dioxidine" the manufacturer indicates that the drug is reasonable to use in the treatment of adult patients. Before the start of the therapeutic course, a tolerance test is mandatory - 10 ml of a 1% medication is injected into the diseased areas and the patient is monitored for another six hours after the procedure. During this period, adverse reactions may occur that are considered contraindications to the use of the drug - your head may feel dizzy, fever and chills are possible. If such phenomena are not fixed, it is allowed to use the composition of the course.
According to the instructions, “Dioxidin” in the form of a solution is recommended for introduction into the affected cavity through a drainage system, syringe or catheter. Most often, a one percent solution is used. A single dosage is from ten milliliters to fifty. Maximum per day in the form of a one percent solution is allowed to use 70 ml of the substance. The manufacturer recommends using the drug once a day or twice, given that the total dose should not be exceeded for 24 hours.
Rules and Features
In the instructions for the use of "Dioxidin" in the ear, vein, nose, wound cavity, foci of inflammation in different parts of the body, it is recommended to use a long therapeutic course. The doctor selects the specific duration, evaluating the tolerance of the composition and the severity of the pathology. In some patients, treatment takes several days, in others up to three weeks, while in others it stretches for a much longer period.
If there is evidence for this, after a while you can repeat the course. In the instructions of "Dioxidine" the manufacturer indicates the need to withstand a month or a half month pause before re-use of the drug.
One percent solution of "Dioxidin" can be used topically, topically. To do this, a gauze dressing is moistened in a liquid and applied to the surface of the wound.
Too much!
The manufacturer in the instructions for "Dioxidine" warns of a possible overdose. You can notice the condition by pronounced side effects (listed below). If a fact of excessive use is detected, it is necessary to consult a doctor to select the optimal symptomatic treatment.
Negative consequences
It is possible to encounter unpleasant consequences when using the composition, if you neglect the instructions and recommendations of a qualified doctor. In particular, according to the instructions of "Dioxidine", the drug is not recommended for children precisely because of the increased likelihood of a negative response from the body. In practice, in some cases, the doctor may recommend the use of the composition. The doctor will explain how to do this correctly, under which symptoms urgently need to refuse treatment. Without a specific education, it is prohibited for a child to prescribe Dioxidine.
Using the composition may cause an allergic reaction. This is often expressed by skin itching, skin rashes. Some develop dyspepsia, headache, shivering, reddening of the skin. There are frequent cases of local skin rashes in the area of contact with the medication.
If the “Dioxidine” used according to the instructions (in the ear, nose, wound cavity, for internal administration) has caused negative adverse reactions, you should consult a doctor. The doctor will evaluate the patient’s condition, cancel the drug or reduce the dosage, and also recommend antihistamines.
It is impossible!
According to the instructions for use, "Dioxidine" for children is not used. Although a minor age is a contraindication, it is stipulated that in some cases the composition can be used, but only strictly under the supervision of the attending physician. The condition of a sick child must be constantly monitored.
You can not use the tool when detecting hypersensitivity or intolerance to any of the compounds present in the composition of the drug. It is forbidden by the instructions for use of "Dioxidin" to a child (in the nose, vein and externally), as well as for some groups of adults - pregnant women and nursing mothers. You can not use the drug with adrenal cortex insufficiency.
The nuances of using
In the accompanying documentation, the manufacturer draws attention to the need to avoid the simultaneous ingestion of the medication in question and alcoholic beverages. The restriction applies to alcohol of any strength level. Alcohol is a toxic substance that negatively affects the functioning of internal systems and organs. With the simultaneous use of degree drinks and an antibiotic for treatment, the toxic effect of both types of products increases.
Performance Nuances
The manufacturer draws attention to the possibility of the formation of resistance in pathological microflora to the active components of the drug. Tests have shown that Dioxidin has no local irritant effect. Intravenous use has a small therapeutic breadth. This obliges especially carefully to observe the established dosage. In the instructions for use, "Dioxidine" (in the nose, externally, for the treatment of foci in the internal organs) is recommended primarily for purulent, necrotic areas, burn lesions. Under the influence of the drug, the surface cleans faster, reparative recovery is activated, and renewal of the epithelium is stimulated. The wound process proceeds significantly more favorably in comparison with the lack of antibacterial treatment.
Experimental studies have shown that the drug has a mutagenic effect. This must be taken into account when evaluating the possibility of using Dioxidin in children. Instructions in the nose, on the wound, in the vein are recommended to be used only in adulthood. Tests also proved the presence of a toxic effect for the embryo, teratogenic effect.
Safety first
According to the instructions, Dioxidin is used with caution in the nose, wound or vein. For example, in any form, regardless of the focus of localization of the inflammatory process, the drug for chronic kidney failure can be used strictly in reduced dosages and only with the ineffectiveness of other medicines that are safer for humans.
Forms and indications
Intravenously "Dioxidin" is used for burn disease, meningitis, accompanied by discharge of pus. The drug is indicated for inflammatory purulent processes, if manifestations of the pathological condition suggest generalization.
Inside the cavities, Dioxidin is indicated for use in pleurisy, empyema, cystitis, peritonitis, as well as a prophylactic.
External use is recommended for deep, superficial wounds that provoked the release of pus. The drug is indicated for trophic ulcers, for a long time not healing violations of tissue integrity. You can use the drug when introducing infection into a burn, with osteomyelitis, if the wounds fester, and also for the treatment of phlegmon. Instructions for use in the nose "Dioxidine" is indicated for acute forms of sinusitis. Also, the drug for local use is prescribed for an abscess, the need for treatment of wounds after surgery. The drug helps with purulent mastitis and skin diseases, one of the symptoms of which is suppuration.
Prices and alternatives
Currently, an average of 140 rubles is being asked for in a pharmacy for one package of Dioxidin. If it is impossible to purchase the composition prescribed by the doctor, you can consider as an alternative the following drugs:
- Dixin.
- "Dioxiplast".
- Hindiox.
Before replacing, consult your doctor. It must be borne in mind that alternative antibiotics can provoke severe adverse reactions, and a therapeutic course will show insufficient effectiveness. To minimize risks, medicines are used strictly under the supervision of the attending doctor.
Stuffy nose. Relevance of the problem
Runny nose is an extremely widespread symptom. It accompanies colds and flu, SARS. A stuffy nose significantly worsens the quality of life, makes you uncomfortable during the day and makes it impossible to sleep at night. Lack of adequate treatment can cause sinusitis. To eliminate the inflammatory process, you can use the instructions "Dioxidine" in the nose. Since it has already been indicated above that the drug is strong enough and dangerous with uncontrolled use, they practice treatment with it only after consulting a doctor.
Antibiotics are effective formulations to eliminate a wide variety of inflammations in the human body. Such medicines quickly destroy pathological colonies, slow down the growth of microflora, but can provoke side effects. "Dioxidine", like some other antibiotics, has a bactericidal and antibacterial effect at the same time. The substance slows down the process of reproduction of microbes and activates their death, harming cell membranes. To get rid of the common cold, Dioksidin produced in ampoules is used in the nose. The drug is not recommended for children for such purposes, but in a particular case, the doctor, having assessed all the dangers and benefits, can recommend such a tactic. Without medical advice, it is forbidden to use the drug to treat a child.
The nuances of using
Dioxidin was developed and manufactured by Russian pharmaceutical companies. At the heart of the drug is quinoxaline. Its effectiveness against bacteria that are resistant to most antimicrobial agents and other chemical therapy agents has been proven. Is it possible to use Dioxidin for inhalation? According to the instructions, this cannot be done, since the manufacturer did not receive a patent for a medicine as a substance from a cold. Therefore, if you need to use it in this way, you will have to strictly follow the recommendations of your doctor. The unauthorized use of the medication is guaranteed to lead to severe side effects.
"Dioxidine" affects the body in a different way than vasoconstrictor drugs. With its use, the mucosa is not irritated, addiction is not formed. The main substances penetrate the sinuses and inhibit the activity of pathological bacteria in these cavities. The drug is effective in treating purulent sinusitis.
Features of use in ENT diseases
Long-term practice has shown that Dioxidin can be used for diseases of the nose, throat, and ear. The drug has a pronounced antiseptic effect, disinfects even hard-to-reach areas of the nasopharynx, destroys the pathogenic microflora in the bronchi. In general, it is recommended to use Dioxidin only with the ineffectiveness of other drugs and the inability to treat with safer methods. Due to the increased risks, “Dioxidine” is usually not used to treat colds and diseases of the ear, throat in children.
In the practice of ENT doctors, “Dioxidin” is usually used if the patient suffers from a prolonged sinusitis accompanied by active purulent discharge, while safer antimicrobials do not show a pronounced effect. In this case, it is recommended to make punctures with subsequent washing of the sinuses with the described composition.
"Dioxidine" is used for diseases of the ENT organs, if other drugs are unavailable for various reasons. If surgery is planned, the medication will help to pre-disinfect the organ.
Application Nuances
If it is necessary to disinfect the ENT organs, Dioxidin should be used in the form of a solution. On sale there are injection ampoules containing a one percent substance or liquid with half the concentration of the active component. The volume of ampoules is 5-10 ml. To treat the nasal cavity, a weaker release format is used in its pure form, and one percent liquid is diluted in half with saline or cold, pre-boiled water.
Upon visual inspection, you can notice the presence of a crystalline precipitate in the ampoule. This is a normal phenomenon, not indicating a decrease in the quality of the composition. The ampoule is first heated in the hands to the temperature of the human body (you can use a water bath), after which it is gradually cooled. If the precipitate is repeated, the drug should not be used. In the absence of crystals, the medication is suitable for use.
How to bury?
As part of a therapeutic course for rhinitis, sinusitis Dioxidin is used for 3-7 days. The specific duration of treatment is determined by the severity of the case. The procedure is quite simple: open the ampoule, add three drops of the substance into each nasal passage with a pipette, introducing it extremely deeply. The frequency of procedures is three times daily. To store the drug, the neck of the ampoule is tightly covered with a cotton swab. The medication should be stored in the refrigerator, just before each instillation, warming in the hands.
The opened ampoule has a shelf life of one day. Unused residues are disposed of. Maximum efficiency can be achieved if, before applying Dioxidin, first rinse your nose with slightly salted boiled water.
The dangers of therapy
The active components of Dioxidin are highly aggressive, which forces them to be used carefully. In particular, its use during the period of gestation or breastfeeding is associated with a risk of penetration of the active compound through the placenta and into milk. This can cause mutations in the body of the fetus, baby.
Until reaching the age of twelve, "Dioxidine" is contraindicated. Based on the studies, doctors confidently argue that a high dosage of the composition can cause DNA changes. If the guaranteed positive effect of the composition is significantly higher than the possible risks, under the supervision of the attending doctor, “Dioxidin” is allowed, but only if more and more safe agents have already been tried and have shown their ineffectiveness - this is possible with a chronic form of purulent sinusitis.
When using Dioxidinum by children it is especially important to strictly observe the doses established by the doctor.
Treatment of sinusitis: possible consequences
As part of the therapeutic course for ENT diseases, Dioxidin is usually used in diluted form, which significantly minimizes the likelihood of side effects. Subject to medical advice and preliminary screening for the absence of allergies, in most cases the drug is well tolerated. There are cases when patients had severely sore and dizzy, he was shivering and feverish, fever. Also, Dioxidin can cause stool and soreness in the intestines. If side effects occur, it is necessary to consult a doctor - the doctor will be able to assess how reasonable it is to continue the course or whether to refuse the medication.
Do I need it?
As can be seen from the many responses, the drug in question is really effective, but it has certain disadvantages. Patients who used it to treat a runny nose, sinusitis, note that it is inconvenient to use the drug. Another important drawback is the lack of direct instructions in the instructions on the possibility of such use of the composition.
But as a means for disinfecting wounds, the substance is effective, works well and rarely provokes side effects, which is why it is considered a good option for purulent and infectious, inflammatory foci.