In the article, we consider the instructions for use with Motilak tablets.
It is a medication that is intended for the treatment of nausea and dyspeptic disorders. The mechanism of its effect on the patient’s body is complex, which is why its high efficiency is due. It is allowed for use with the aim of treating children from 5 years old.
Pharmacological forms
According to the instructions to Motilak, the drug is available in two pharmacological forms - oral tablets and tablets intended for resorption. Packages containing 10 or 30 tablets are on sale, while the dosage of the active ingredient in both forms of the drug is the same.
Composition, description of the drug
As the instructions to Motilak indicate, the main active ingredient in the composition is domperidone. First of all, the active component is able to affect the activity and activity of the vomiting center located in the brain, but on the outside of the BBB. Against the background of the use of the drug, the activity of this zone is suppressed, as a result of which the patient has a feeling of nausea and the development of vomiting is prevented. Motilak is also effective in vomiting, which is provoked by a variety of reasons:
- Pathologies of the digestive tract, which are in a chronic form.
- Eating new food or one that is difficult to digest.
- Diseases of infectious etiology.
- The use of medications.
Motilak is able to improve the contractility of the digestive tract, mainly the gastric muscles. This contributes to the fact that the lump of food is pushed with greater speed, the patient disappears discomfort and a feeling of heaviness. It is effective in diseases accompanied by dyspeptic symptoms (belching, flatulence, heartburn) and stagnation of food. If a person is healthy, then a feeling of fullness in his stomach can develop after eating fried foods or eating excessively large portions of food. In these cases, a one-time use of the medication is allowed in order to eliminate discomfort. In addition, the medicine is often used to treat a variety of diseases.
Through the blood-brain barrier, the drug penetrates poorly, but has a central effect. Nevertheless, extrapyramidal side effects develop quite rarely.
Any of the pharmacological forms of the medication contains a number of auxiliary components, among which sugar is present. In this regard, patients suffering from diabetes mellitus and disorders of carbohydrate metabolism, it is important to be careful when using the drug.
It does not affect the rate of gastric secretion, but it is able to influence the synthesis of prolactin.
The instruction manual for Motilak is very detailed.
The drug belongs to the group of antiemetic drugs with a central type of exposure. It is an antagonist of dopamine receptors.
Indications for use
In accordance with the instructions for use of Motilak, adult patients are recommended for use if there is a need to eliminate the symptoms of dyspepsia provoked by a slowdown in the process of promoting food through the digestive tract:
- Heartburn.
- Abdominal pain.
- Flatulence.
- Bloating.
- Burping.
- Feelings of overflowing stomach.
In addition, the medication is able to effectively stop nausea and vomiting, which have the most diverse etiology:
- Provoked by antiparkinsonian medications.
- Caused by chemotherapy or radiotherapy.
- Intoxication.
- Medicinal
- Infectious.
- Organic.
- Functional.
In pediatric patients, the drug is prescribed in the same cases as in adult patients with the goal of stopping vomiting and various dyspeptic manifestations. Allowed its use in children from 5 years.
In accordance with the official instructions of Motilak, its use in the treatment of women in the last two trimesters of pregnancy is acceptable. Treatment in the first trimester can be carried out, but only if the doctor considers the use of Motilak appropriate.
Dompiridone is excreted in breast milk in small quantities, however, the mechanism and consequences of exposure to the active component in newborns are not fully understood. That is why experts recommend refraining from using Motilak in the lactation period. If there is an urgent need for its use, a woman needs to transfer the child to artificial feeding before starting a course of therapy.
Contraindications
What else can you learn from the instructions for Motilak tablets? Inadmissible application is only in a few cases:
- In conditions where increased gastric motility is contraindicated - with organ perforation, obstruction, bleeding.
- If the patient is diagnosed with prolactinoma.
- If the patient has an individual hypersensitivity to any component of the drug.
- At the age of less than 5 years.
Below we consider analogues.
Instructions for use "Motilaka"
The standard single dose is one tablet, which is equivalent to 10 mg of the active ingredient. The amount of drug used can be doubled if there is such a need.
For the treatment of chronic digestive disorders and dyspeptic symptoms, it is shown to use 10 mg of dompiridone three times a day. The third method is preferably carried out before bedtime. The digestibility of dompiridone decreases if you take it after eating. In this regard, doctors recommend taking the pill no later than half an hour before meals.
In order to stop acute conditions (vomiting, overeating, nausea), adults are shown the use of 20 mg of the active component, which is equivalent to two tablets. It is allowed to repeat receptions up to 4 times during the day.
If the patient has impaired renal or hepatic functionality, the specialist should adjust the dose. As a rule, a reduction in the frequency of doses of the drug is made.
What does the instruction manual for Motilak for children tell us?
For children, the dosage should be determined by the pediatrician taking into account the patient's age and weight. Children from 5 years old should be prescribed 5 mg of dompiridone per 10 kg of weight. The medication should be taken four times a day.
In order to treat women in the lactation period and during pregnancy, the dosage should be used, which the doctor determines individually in each case.
Negative impact
According to the instructions for use and reviews of "Motilak", against the background of its use, the patient may develop some undesirable effects, including:
- Allergic manifestations in the form of skin itching, rash.
- An increase in blood levels of prolactin, dysmenorrhea, gynecomastia - from the endocrine system.
- Drowsiness, convulsions, extrapyramidal symptoms - on the part of the National Assembly.
- Dry mucous membranes in the oral cavity, constipation, cramping - from the gastrointestinal tract.
If any of these negative manifestations appears, it is important to seek the advice of a specialist.
Interaction with other medicines
Before starting use, the patient should notify the doctor about the drugs that he is taking. This will avoid drug interactions.
The effect of Motilak is neutralized, and its use becomes ineffective if it is used in conjunction with anticholinergic medicines.
Its bioavailability is significantly reduced if it is taken together with antacids and drugs that inhibit gastric secretion.
Some drugs with the ability to affect the activity of liver enzymes, when used in parallel with Motilak, change the level of dompiridone concentration in the blood plasma.
Parallel therapy with digoxin and paracetamol preparations is allowed - the concentration of these substances in the blood under the influence of Motilak does not change.
Special instructions for use
The metabolism of dompiridone after taking Motilak occurs in the tissues of the liver. This explains the recommendation to use the drug with caution in the treatment of patients suffering from liver failure.
Patients with impaired renal function, and who are shown the long-term use of Motilak, are shown careful monitoring.
It is important to maintain a two-hour interval between the use of the medication and antacid drugs. A similar rule should be observed for drugs that inhibit the proton pump.
Psychomotor reactions against the background of the use of Motilak are not disturbed, therefore, the drug can be used by drivers and workers whose activities are associated with the management of complex mechanisms. This possibility is due to the fact that the medication does not provoke the development of dangerous unwanted effects.
Overdose
As a result of a significant excess of the recommended dose, the severity of side effects increases. Some patients suffer from extrapyramidal disorders such as impaired muscle tone, speech, cramps, disorientation, and drowsiness.
Overdose therapy involves the use of symptomatic medications - anticholinesterase and antihistamines. This will allow in a short time to stop unpleasant symptoms. In addition, the use of activated carbon is indicated for the purpose of removing excess dompiridone from the body.
Analogs
If necessary, Motilak can be replaced with a similar medication. The most popular are: Motizhect, Tserukal, Metoclopramide, Ganaton, Domstal-O, Motilium.
If you need to replace the drug, it is important to consult with your doctor first.
We will not consider the instructions for the analogues of Motilak in detail.
In Russian pharmacies, the average cost of a medicine is 255 rubles per pack.
Reviews
Numerous reviews of people who used the "Motilak" indicate that it effectively and quickly stops dyspeptic disorders such as bloating, heartburn and belching.
The undoubted advantage of the drug is that it is allowed for use in the treatment of children, has a small number of contraindications, rarely causes serious unwanted effects.
However, you should consult your doctor before using it. We reviewed the instructions and reviews for Motilak.