According to the latest data, in Russia every year, 54,000 women are diagnosed with breast cancer. And the beautiful half of humanity, unfortunately, hears this diagnosis more and more often. But medicine does not stand still. Effective remedies are being developed to combat a terrible disease. One of them is the Tyverb. Instructions for use of the named drug, as well as its generic Tykerb will be offered to you later in the article.
Where can Tykerb and Tyverb buy cheaper?
In Russia, both a branded drug and its analogue can be ordered and purchased on the website of a well-known Indian company with a serious reputation, . In order to provide services, you will need the availability of documents confirming the need for treatment.
For Tayverb, the price (for branded product) in Moscow, for example, is now kept at 163,000 rubles. While buying a generic will cost you 40,600 rubles. As you can see, the difference is significant. Therefore, for those to whom it is too expensive to buy “Tyverb”, the generic Tykerb will be an affordable means with which you can save your health and even life.
About the generic drug
The generic of the described drug is Tykerb, manufactured by GlaxoSmithKline (India). It has the same main active substance, and therefore, an absolutely similar effect. But for patients suffering from such a serious illness and forced to spend large sums of money on treatment, it may turn out to be much more affordable than the brand name Tyverb.
After all, it is no secret that when a generic company is issued, a licensed company does not spend money on development, testing and advertising, so the cost and retail price of such medicines are much lower. And this, by the way, does not affect the effectiveness of the produced medicine.
When the drug is used
The main active ingredient of this drug is a tyrosine kinase inhibitor - lapatinib. It suppresses the effect of the mutant tyrosine kinase protein, due to which healthy cells are transformed.
Such a protein molecule is also HER2 receptors. They are located on the surface shells of breast cells or inside them, and in the case of overexpression, these cells are forced to actively and uncontrollably divide, which makes the development of the disease particularly aggressive.
In such cases, the drug Tyverb is prescribed. It is usually combined with “Capecitabine” for patients with locally advanced or metastatic cancer, in whom the pathology progresses both after Trastuzamb therapy and against its background. Also effectively described is a combination with an aromatase inhibitor for postmenopausal patients in the diagnosis of hormone receptor-positive metastatic cancer.
How to use "Tayverb": instruction
The described tool is available in the form of tablets, which should be taken only as prescribed by the doctor, once a day, one hour before or one hour after eating. The interval between doses of the medication should be 24 hours, and it can not be reduced.
If you have to miss the appointed time, it is strongly recommended that you wait for the next dose.
The dose is determined depending on the type of disease:
- So, for patients with metastatic pathology, it is 1250 mg of the drug "Tyverb" and 2000 mg of "capecitabine."
- In the case of a hormone-sensitive tumor, take 1500 mg of the main drug with an aromatase inhibitor, in an amount of 2.5 mg.
Contraindications
The described tool is contraindicated during pregnancy and lactation. It is not prescribed for children, since there is no sufficient information about the effect of the drug on the child's body. It is prescribed with caution in case of impaired liver function, renal failure (for patients after 65 years) and in conditions that can lead to left ventricular failure.
Side effects
Drugs containing lapatinib can cause side effects. So, in patients when taking Tyverb tablets, general weakness, signs of anorexia, and a decrease in LVEF are often observed (which is mainly asymptomatic and is restored when the drug is canceled). There are also symptoms of diarrhea, a skin rash (which goes away on its own and does not require withdrawal of the drug) and nail damage.
Treatment with the named agent should be carried out only under the strict supervision of a specialist!