"Traklir" (bosentan) refers to a group of vasodilating (vasodilating) drugs. Their use creates the effect of expansion in blood vessels, due to the relaxation of the muscle layer of the walls of the latter. And this, in turn, makes it possible to increase the efficiency of organs, since their supply of oxygen from the flowing blood improves.
Next, you will be offered a description of the drug "Traklir", the price of this tool, as well as favorable offers for its purchase.
Where better to buy "Traklir": price
Buy drugs for treatment chronic diseases are often quite expensive for patients. This is compounded by the fact that such a person, as a rule, does not have the opportunity to earn money to buy them. After all, the patient has reduced working capacity, and even is completely disabled. Well-known Indian company Cipla Ltd. produces a generic of the described drug - Bosentas, which has the same active substance, and therefore the same therapeutic effect.
On "Traklir" the price in Russia is within 200 000 rubles, and on the website You can get its generic almost 10 times cheaper . For this you will need to submit only a document confirming the need for such treatment.
The low cost of the tablets is due only to the fact that their manufacturer does not need to spend money on the development, testing and promotion of the drug on the market. At the same time, its quality remains at a high level. In this case, cheap does not mean bad.
Indications
The named tool is available in the form of tablets. It is prescribed to patients (adults and children from 3 years of age and older) with certain pathologies:
- with primary (hereditary or idiopathic) pulmonary arterial hypertension (PAH), to improve clinical manifestations in patients with a diagnosed II-IV functional class of the disease and to increase tolerance to physical activity;
- with secondary pulmonary arterial hypertension (PAH), proceeding against the background of systemic scleroderma;
- with PAH, resulting from heart disease with impaired hemodynamics.
"Traklir" is also prescribed for systemic scleroderma and the progression of ulcerative lesions of the upper or lower extremities, to reduce the number of new ulcers.
Dosage
These tablets are taken twice a day, without correlating it with food intake - in the morning and in the evening. At the initial stage, the appointment of the drug and monitoring of therapy should be carried out only under the supervision of an experienced specialist.
The dose of Traklir, as a rule, is 62.5 mg in the first 4 weeks of treatment, and then it is increased to 125 mg. In some patients, a dosage increase of up to 250 mg is possible.
For children, the drug is prescribed depending on body weight.
Contraindications
"Traklir" is not assigned:
- children under 3 years old;
- pregnant
- lactating;
- suffering from severe arterial hypotension;
- moderate and severe liver function;
- having increased sensitivity to the components of the drug.
Caution should be used in patients with mild hepatic impairment.
Special instructions for taking the drug "Traklir": instructions
During therapy, the activity of hepatic transaminases should be monitored once a month. With subsequent increases in the dose of the drug after 2 weeks, the activity of these enzymes should also be checked.
In case of manifestations of associated clinical symptoms of liver dysfunction (nausea, abdominal pain, apathy, fatigue, jaundice), treatment with Traklir should be discontinued.
The instruction for the named remedy, in addition, suggests examining women of reproductive age for absence of pregnancy before treatment. And in the course of therapy and within 3 months after it, they should use reliable contraceptives. Since the use of the described drug reduces the effectiveness of hormonal contraceptives, patients should use additional methods to prevent pregnancy.