In colds, as a rule, the mucous membranes of the nose and paranasal sinuses are the first to be affected by viruses, causing inflammatory processes.
In most cases, pathogenic bacteria also join them, due to which a purulent runny nose appears, as well as sinusitis, otitis media and other diseases. In such cases, local medicines with an antibiotic are in demand, which include the Isofra spray. At what age can the drug be used for children?
Spray is considered an antimicrobial agent for external use. It is used to treat infections and inflammatory processes with localization in the ENT organs, which are provoked by bacteria that are sensitive to the medication.
What is included in the spray?
The medicine "Isofra" for rhinitis and other infectious otolaryngological diseases is made in the form of a spray. The manufacturer - the French pharmaceutical organization Laboris Boshara-Recordati - offers medicine in plastic bottles of fifteen milliliters in volume with a dispenser-sprayer.
The main active component of the spray is framycetin sulfate. Its concentration in one milliliter is 12.5 milligrams. The additional components of Isofra are the following components:
- Sodium salt of hydrochloric acid.
- Preservative E218.
- Tribasic carboxylic acid.
- Distilled water.
Spray "Isofra" is dispensed in vials of fifteen milliliters.
Pharmacological properties
The active component of the drug is considered an antimicrobial agent, which refers to aminoglycosides. It has a bactericidal effect (leads to the death of bacterial cells) in relation to a large number of different pathogens, including both gram-positive and gram-negative bacteria, which provoke inflammation of the ENT organs.
The bactericidal effect occurs due to damage to the bacterial cell cytolemma and violation of the intracellular connection of proteins. With external use, the active component of the drug is not absorbed into the general bloodstream.
The drug eliminates:
- Staphylococci.
- Pseudomonas aeruginosa.
- Shigella.
- Hemophilic sticks.
- Salmonella.
- Enterobacteria.
In addition, it should be noted that the pathogens to which the active substance of the drug, as a rule, acts, may not be sensitive to the Isofra medication. This may indicate a lack of positive dynamics after several days of therapy. If five days after the start of treatment, the discharge does not become smaller, and the nasal passages are still blocked, you need to contact a medical specialist.
But the drug does not act on a certain type of bacteria, for example, on anaerobic microbes or pneumococci. Do not use the drug for viral lesions of the nasopharynx (acute respiratory viral infection, influenza). At what age can Isofru be used (according to the instructions for use)?
According to the annotation, the drug can be used from one year. If there is a need to use the spray at an earlier age, then you should consult a medical specialist and get his approval.
At what age can Isofra be given to children? Clinical trials have confirmed the effectiveness of therapy for babies up to one year old and women in an interesting position. But still, the drug is recommended for use in such cases only in emergency situations.
Indications and contraindications
The use of Isofra spray is indicated for the following diseases:
- Rhinitis (swelling of the mucous membrane of the nasal cavity, which occurs due to the penetration of an infection in the nose or allergic components or hypothermia).
- Pharyngitis (acute or chronic inflammation in the mucous membrane of the posterior pharyngeal wall, often of a viral or bacterial nature).
- Sinusitis (an infectious and inflammatory process that affects the mucous membrane of the paranasal sinuses).
- Sinusitis (inflammatory lesion of the paranasal sinuses of the nasal cavity).
- Rhinopharyngitis (an inflammatory disease characterized by damage to the oropharynx).
- Tonsillitis (inflammation in the tonsils, which occurs due to the action of bacteria or viruses on the lymphoid tissue).
- Etmoiditis (acute or chronic inflammation of the mucous membrane of the cells of the ethmoid labyrinth).
- Frontite (inflammatory disease of the frontal sinuses).
An absolute prohibition on the use of Isofra spray is the individual intolerance to framycetin sulfate or additional substances.
Mode of application
According to the instructions for use, the spray "Isofra" is used intranasally. They irrigate the nasal mucosa, while the bottle must be kept upright. The average dosage for adult patients is from four to six irrigations per day. The duration of the course of therapy should not exceed 10 days.
The drug must be injected into each nasal passage from one to four drops six times a day into each nostril no more than once every two hours.
To get the maximum effect from the spray, vasoconstrictor drops should be used in about twenty minutes in advance, for example, Naftizin, Galazolin, Ximelin. When breathing becomes freer, you need to blow your nose.
Dosage of the drug for children
Small patients receive one irrigation in each nasal passage three times a day. The duration of treatment for children is no more than seven days.
Otolaryngologists in most situations prescribe Isofra spray for small patients with adenoid growths. In clinical trials, it was confirmed that the drug significantly reduces the size of the growth, which is associated with a change in the bacterial microflora in the nasopharynx under the influence of the drug.
At what age can Isofru drip into my nose?
Spray is not recommended for the treatment of children under one year of age. But exceptions are possible, and the medication can be prescribed by the doctor much earlier (from one month).
The spray helps to carry out uniform processing of the nasal mucosa, and the active component penetrates into the blood of babies in small quantities, which does not cause any adverse reactions. Therefore, do not be afraid that such a small child is prescribed an antimicrobial drug in the nose.
Using this medicine, you can avoid taking oral antibiotics, which is often accompanied by the appearance of adverse reactions, allergies and a violation of the natural microflora in the body of the child.
Pregnancy
Spray "Isofra" during an interesting position of a woman can be prescribed by a doctor if there is a likely benefit and there is no risk for both the mother and the unborn child.
Absorption of an antimicrobial agent in the blood is practically not carried out, in this regard, the medication, as a rule, is not forbidden to use by pregnant women and with breastfeeding.
Adverse reactions
As a rule, Isofra spray is well tolerated by patients. Sometimes during therapy there are local negative effects in the form of allergic reactions.
Features
Before starting treatment with a spray, you should thoroughly familiarize yourself with the annotation to the medication. There are several special instructions that include:
- Using the medicine for more than ten days can lead to a violation of the microflora of the nasal mucosa and the appearance of dysbiosis.
- The lack of improvement after starting to use the spray for ten days is considered the reason for adjusting therapy.
- The medication does not affect the speed of psychomotor reactions and attention.
In pharmacies, the Isofra spray is dispensed without a prescription from a medical specialist. If you have questions or doubts regarding its use, you should consult a doctor.
There is no evidence of exceeding the recommended pharmacological dosage of Isofra spray today.
Storage conditions
The shelf life of the Isofra spray is 36 months from the date of manufacture. Keep the medication in a place inaccessible to children at an air temperature of no more than +25 degrees.
Analogs
"Isofra" is an antimicrobial drug from the group of aminoglycosides. According to the active ingredient - framycetin - the spray does not have generics. But there are similar drugs of one therapeutic group, for example:
- Framinazine.
- "Polydex".
- "Bioparox".
- "Rinofluimucil."
- "Vibrocil."
- Protargol.
Of the non-aerosol form drugs, inexpensive Protargol drops should be noted. Despite the fact that “Protargol” has a completely different composition than that of “Isofra,” these two medicines are considered the most similar in their effect.
In the structure of Protorgol there are three more active components that are not available in Isofra, therefore Protargol has a more versatile effect on the patient's body.
"Vibrocil" is a medicine that has a pronounced anti-inflammatory, as well as vasoconstrictive and anti-allergic effect. The drug copes with various types of rhinitis and sinusitis. This generic "Isofra" is not recommended for use for more than fourteen days, since prolonged vasoconstrictor action can provoke a runny nose. In addition, dosing should be strictly observed.
"Rinofluimucil" - anti-inflammatory, as well as vasoconstrictor and decongestant medication - a good substitute for Isofra. Effectively dilutes the pathological secretion in the nasal membrane, copes wonderfully even with severe types of sinusitis or rhinitis. "Rinofluimucil" has certain limitations, it is not recommended to give it to children under three years of age, and also to use it for a long time, as addiction is possible.
Bioparox is effective not only in the treatment of infectious lesions of the nasal membrane, but also in the treatment of bronchitis, as well as laryngitis and tonsillitis. The antimicrobial component contained in its structure copes well with pathogens. In most cases, Bioparox is used after the Isofra therapy course has ended. In rare situations, Bioparox is even more effective medication.
"Polydex" is a multi-component spray that has not only anti-inflammatory and antimicrobial effects, but also a vasoconstrictor. Although the compositions of Polydex and Isofra are completely different, the clinical effects are similar. Negative effects after using "Polydex" are extremely rare, but there are a huge number of prohibitions.
Framinazine is the best known substitute for Isofra. The medication belongs to the same therapeutic group of antimicrobials as Isofra, and copes with infection and inflammation just as effectively as the described drug. "Framinazine", as a rule, is used for prophylactic purposes in inflammatory processes after surgical interventions. Both drugs can not be used for more than ten days. The average price of a spray in pharmacies varies from 270 to 450 rubles.
Opinions
Reviews of these drops in the nose are usually positive. Patients narrate that the drug helps well in the early stages of the disease. With viruses, such nasal drops are ineffective. Most managed to eliminate rhinitis in a couple of days, but then there were problems of regeneration of the microflora of the nasopharynx.
Reviews about "Isofra" with sinusitis do an excellent job with this ailment. Improvements occur already on the third day, but if this does not happen, it is recommended to cancel the drug therapy. There are situations when it was possible to eliminate the disease in their chronic form with their help. Doctors themselves often prescribe a medicine for sinusitis.
Many parents are interested in how old isofru children can take the drug and whether it can be injected into a child up to one year old. The correct answer is not worth it.
The instructions for use for Isofra for children indicate that a doctor must authorize the use of the drug. It is he who can conclude the nature of the disease. Most mothers try to self-medicate and do not get the desired effect. The same patients who used the medication for their intended purpose, consider it an excellent medicine for the common cold, as well as sinusitis and sinusitis.
The drug has excellent performance and responses with inflamed glands. The cost of Isofra for children is quite acceptable, especially since the medication has a short course.
The minus of the drug, patients call it an unpleasant taste, which is not to the liking of children. In addition, parents note that irrigation is carried out with quite a lot of force, this causes certain concerns. Some mothers are afraid of negative effects, because the drug "Isofra" is considered an antibiotic. But the experience of most parents and doctors shows that small patients tolerate the medication, as a rule, well, and the infection quickly disappears.
If used improperly, the drug will not have a positive effect and may even become addictive, which is why in the future it will be necessary to use stronger medicines to eliminate bacterial sinusitis or rhinitis.