In the article, we will consider which drugs with pyelonephritis are the most effective. This is one of the most common nephrological pathologies. The disease can affect the renal pelvis along with the parenchyma, causing a violation of urination in combination with pain in the lumbar region. Such a disease can even end with an abscess. Not the most pleasant consequence of the acute form is its transition to the chronic stage, which is much more difficult to treat. That's why it is important to diagnose this disease in time and start taking the necessary medications for pyelonephritis.
How is the therapy going?
This disease is fought through the use of the following drugs:
- The use of analgesics. Most often these are combined medicines, which include painkillers and antispasmodics. The use of anti-inflammatory non-steroid drugs is not recommended due to their nephrotoxicity.
- Treatment with antipyretic drugs. As a rule, “Paracetamol” is prescribed. By the way, in fairly high doses (up to 1 thousand milligrams), he is quite capable of relieving pain.
A review of drugs for pyelonephritis: antibiotics
In order to eliminate infectious agents, antibiotics are used along with antimicrobial agents of various groups. In the presence of pyelonephritis, drugs should be selected on the basis of urinalysis data, which reflect not only the pathogen, but can also help establish its sensitivity to a particular type of medication in a particular patient.
What medications to take with pyelonephritis, it is better to check with your doctor. Unfortunately, in our country, the methodology for selecting antibiotics in accordance with the effectiveness or ineffectiveness of treatment has taken root more, although initially a correctly selected remedy can significantly accelerate therapy. Such drugs for kidney pyelonephritis, such as antibiotics, belong to the following groups:
- Means of the penicillin series (we are talking about Amoxicillin, Ampicillin and others), this also includes combinations of penicillins with clavulanic acid, for example, Amoxiclav. With pyelonephritis, this category of drugs has been used for a very long time and quite successfully.
- The use of injectable cephalosporin antibiotics of the second and third generations (for example, "Cefotaxime", "Cefazolin").
It is important to note that antibiotics in the presence of pyelonephritis and cystitis, as well as with other infectious pathologies, are taken with mandatory minimum courses for a week, and if necessary, the duration of antibiotic therapy can be increased to two weeks. What medications for pyelonephritis are better to buy, it is sometimes difficult to decide.
Effective Antimicrobials
Another category of drugs that fight infections with diseases of the urinary system are antimicrobials, which are synthetic compounds of the following chemical groups:
- Fluoroquinolones (for example, “Ciprofloxacin” along with “Norfloxacin”, “Ofloxacin” and others). It should be emphasized that in the treatment of urological pathologies, the drug of choice is Norfloxacin.
- The use of nitrofurans ("Furadonin" or "Furamaga" and so on). These are quite old, but at the same time effective means.
- The use of oxyquinolines (for example, "Nitroxoline"). This is a very long known category of drugs, but due to its active use in the treatment of diseases of the urinary system, the sensitivity of a large number of microscopic organisms to them has significantly decreased in recent years.
- Treatment with sulfonamides. This is a well-known medicine for pyelonephritis called Biseptol, which does not currently have the necessary effectiveness in the fight against infections.
- Derived medicines of phosphonic acid. Today it is the only means of "Fosfomycin." In pharmacies, it is sold under the original trade name "Monural". In the presence of pyelonephritis, such a drug is not used so often and, as a rule, it is prescribed for the treatment of cystitis. But it is worth emphasizing its powerful, and at the same time rapid antimicrobial effect on the entire urinary system. The medicine "Monural" is a rather effective medicine for chronic pyelonephritis, which can be prescribed as part of a comprehensive treatment of the disease. It is often prescribed in the complex treatment of the disease.
- The use of uroseptics is very common. They are one of the main categories of drugs, along with antibiotics, because they act on the urinary tract. Almost all antibiotics can be attributed to this class, since they usually pass through the kidneys, and their withdrawal is carried out with urine. But the best uroseptic will be the one that can maximally maintain antibacterial activity against the background of output through the urinary ducts.
Plant-based products
What medications to drink with pyelonephritis are interesting to many patients. In the complex therapy of inflammation of the kidneys, herbal remedies are often used. This can, for example, be independent medicinal herbs like bearberry, lingonberry, birch buds and multicomponent collections, or medicines based on various plants.
Quite effectively, “Fitolizin” acts in the presence of pyelonephritis. This drug is a vegetable-based paste that is diluted with water and taken orally. The composition of the medication contains extracts of birch leaves, horsetail grass, parsley root, knotweed, and so on. The drug can have anti-inflammatory, antimicrobial, diuretic and antispasmodic effects.
To date, there are many different medical methods for the treatment of pyelonephritis. But only a doctor can correctly select them, therefore, in case of signs of an inflammatory process in such an organ as kidneys or back pain, you should consult a specialist.
Instructions for the use of diuretics
Diuretics are diuretic drugs. They are prescribed for pyelonephritis when, in the presence of vivid symptoms of the disease, a diet with limited salt intake and drinking regimen does not lead to an effective emptying of the bladder. And also apply these drugs with severe swelling to withdraw the accumulated fluid. At the same time, “Furosemide” and “Lasix” are very common medications.
Furosemide is prescribed intravenously in the form of injections exclusively for concomitant diseases that disrupt the absorption process of the drug within the intestines, as well as when an urgent effect is required from the administration of the drug. The initial dose of the drug against the background of intravenous injection is 40 milligrams, after which it is recommended, with insufficient urinary excretion, to switch to oral forms of the drug. A doctor must prescribe a dosage, because it depends on the severity of edema, arterial concomitant hypotension, and other factors.
In combination with the use of diuretics in the presence of pyelonephritis, it is recommended that specialists undergo hemodialysis along with hemosorption, plasmapheresis, and also take a solution of potassium, sodium and calcium salts to prevent disturbance of water and electrolyte balance. Against the background of improving disease indicators, doctors gradually prescribe weak diuretics to patients, for example, after Furosemide they recommend switching to lighter drugs or alternative methods (tincture of parsley root).
How long to take medication?
Medicines for pyelonephritis in adults are taken for seven days, and then tests are given, according to the results of which the doctor determines the need for their subsequent use. They do not recommend using diuretics on their own, sometimes you can resort to folk recipes and drink, for example, green tea to increase urinary outflow, but it is better to coordinate any medical procedures with a doctor. Is it always possible to drink medications for pyelonephritis? There are many contraindications for the use of such drugs, which people can not guess on their own.
Contraindications
Often, diuretic drugs, together with visible positive effects, for example, removal of puffiness, can cause harm to the body. There are the following contraindications for their use:
- Kidney failure with anuria.
- Hepatic coma.
- The presence of severe electrolyte imbalance.
- The presence of hypovolemia.
- The presence of a pronounced violation of the outflow of urine.
- The presence of digital intoxication.
Medicines for kidney pyelonephritis in women
Treatment of pyelonephritis usually begins with antibiotics. No alternative method is able to cure the body of the presence of pathogenic bacteria. The causative agent of this pathology in women is most often Escherichia coli, in connection with this they use drugs to which it is sensitive. These include penicillins and cephalosporins along with fluoroquinolones and ciprofloxacins. For example, for treatment, women are often prescribed “Cefotaxime” and “Cefazolin”. After the appointment of antibacterial drugs for pyelonephritis in a woman, the symptoms subside within the first days.
Antispasmodics
In addition to antibiotic therapy, treatment is supplemented with antispasmodics, as well as diuretics, anti-inflammatory drugs and uroseptics. Antispasmodics are required in order to improve the normal urinary outflow from the inflamed kidney, and if this does not help, stenting of the ureters is used. Diuretics and uroseptics fight microbes, and anti-inflammatory drugs suppress the foci of inflammation in the infected organ. If patients have good tolerance of bee products and herbal medicine, they can be used as traditional medicine.
Prevention Products
The scheme and methods of preventing this disease require a diet, and at the same time a drinking regimen, along with the use of uroseptics and diuretic drugs. It will also require therapy of pathologies causing pyelonephritis (urinary tract infections and cystitis).
The use of bacteriophages for the treatment of this pathology
Sometimes, when antibiotics fail to positively affect the source of pathology or because of intolerance to modern methods, it is proposed to use bacteriophages, which are special drugs designed to selectively infect cells of pathogenic bacteria, for example, streptococcus, staphylococcus, dysentery bacillus and Klebsiella.
Finally
Thus, medications are the main tools in overcoming the disease. Each form and severity of the course of the disease dictates its own list of different groups of drugs that must be used without fail. Be sure to use antibiotics for the development of pyelonephritis, which affect the causes of the pathology and destroy it.
There are several categories of antibacterial drugs that are used for this disease, often they use a wide range of drugs, for example, cephalosporins in combination with penicillins and so on. For symptomatic treatment of various manifestations of this disease, diuretics are used along with antipyretic and anti-inflammatory drugs and other drugs necessary for treatment. We examined which medications for pyelonephritis are the most effective.