Sodium acetate trihydrate: instructions for use

Sodium acetate trihydrate is a regulator of water-electrolyte and acid-base balance. Plays an important role in the body. The substance is responsible for the compensation of sodium salts and acetate ions. The component produces the following therapeutic effect:

1. Detoxification.
2. Rehydrating.
3. Diuretic.
4. Plasma replacing.

Sodium acetate trihydrate and sodium chloride are different substances. The first component is the sodium salt of acetic acid, the crystals have a weak vinegar aroma. And sodium chloride is the sodium salt of hydrochloric acid.

Together they form a combined saline solution used for detoxification and rehydration.

Chemical properties

Sodium acetate is a white, hygroscopic, fine powder that dissolves in water. It decomposes at 324 degrees Celsius. The molecular weight is eighty-two grams per mole for the anhydrous form.

Formula sodium acetate trihydrate: CH3COONa * 3H2O.

Indications and contraindications

This substance is prescribed for rehydration in the presence of the following ailments:

1. Hyperkalemia (a pathological disease that provokes an abnormally high content of potassium in the blood).
2. Cholera (an acute intestinal infection caused by the bacteria Vibrio Cholera).
3. Acute dysentery (acute bacterial intestinal disease, which is characterized, as a rule, by a violation of the mucous membrane of the large intestine).
4. Foodborne infection (acute intestinal disturbances provoked by the intake of products that contain harmful microorganisms and their toxins).

The following conditions are considered restrictions on the use of:

1. Increased Sensitivity.
2. Kidney disease.
3. Lesions of the liver.

With extreme caution, sodium acetate trihydrate is used in the following cases:

1. The age of the patient is up to eighteen years.
2. Retirement age.
3. Pregnancy.
4. Lactation.

Side effects

Like any other medicinal substance, sodium acetate trihydrate can provoke certain negative reactions in the human body:

1. Swelling.
2. Tachycardia (a sharp increase in heart rate).
3. High blood pressure.

If signs of poisoning occur, hemodialysis and symptomatic therapy are performed. Toxic dosage - 100 grams.

annotation

According to the instructions for use, it is known that the drug is used intravenously under the control of laboratory parameters. The parameters of the fluid used and the amount of urine are checked every six hours. Within an hour, the solution is administered in a concentration that is from 7 to 10 percent of the patient’s weight.

Next, the jet infusion is replaced by a drip, which lasts for forty-eight hours at a speed of 40 to 120 drops per minute. Before injection, sodium acetate is heated to 36-38 degrees. The solution is administered in the dosage that is necessary to resume the amount of fluid that was lost with feces, vomiting, as well as urine and sweat.

Treatment begins with a jet infusion of the drug with the subsequent transition to drip in the following severe forms of the disease:

1. Hypovolemic toxic shock (a life-threatening condition that is caused by poisoning of the body by components secreted by pathogenic microorganisms).
2. Decompensated acidosis (a pathological process in which the alkaline balance of the blood gets lost, namely, a low concentration of bicarbonate in such a biological fluid is noted).
3. Anuria (a disease in which urine does not enter the bladder, and, as a result, does not stand out from it).

Interaction with other drugs