The drug is an analeptic that has a positive effect on the vasomotor and respiratory centers in the medulla oblongata.
The drug is dispensed from the pharmacy in the form of drops for oral administration, this drug is sold in dark glass bottles of fifteen, twenty-five and thirty milliliters. According to the instructions for use, "Cordiamine" in ampoules is also available.
Structure
The main active ingredient is niketamide, in one milliliter of drops its concentration is reached in the amount of 0.25 milligrams. In addition, the structure of "Cordiamine" includes additional trace elements.
What properties does the drug have?
A medication is a respiratory stimulant with a mixed mechanism of action. "Cordiamine" has a positive effect on the respiratory and vasomotor centers, which are located in the medulla oblongata, and also affects the receptors of the peripheral nervous system.
When drops are used inside, the vasomotor center is activated , as a result of which there is an instant narrowing of the vessels and, as a result, blood pressure rises.
The peripheral effect of the drug is due to the action of the active substance on the nerve endings of the site, which affects the depth and frequency of respiratory movements.
In the reflexogenic site there is a huge number of receptors responsible for oxygen saturation. That is, when oxygen becomes less, these nerve endings respond to the signal, then they stimulate rapid breathing through the ganglia.
"Cordiamine" does not have a definite effect on the functioning of the myocardium; all the properties of the drug are revealed at the level of reflexes.
Indications
According to the instructions for use of Cordiamine, drops are prescribed to people for the elimination and treatment of the following diseases and pathologies:
- Collapse (a life-threatening condition characterized by a drop in blood pressure and a deterioration in the blood supply to vital organs).
- Disruption of the cardiovascular system.
- Suffocation.
- Shock (response of the body to the action of external aggressive stimuli).
- Respiratory depression and oxygen starvation.
- Severe hypotension (a condition characterized by low blood pressure).
- Overdose of barbiturates, analgesics.
Contraindications
The drug "Cordiamine" is allowed to be used only as directed by a medical specialist. Before using the drug, you must thoroughly familiarize yourself with the instructions for use. The medication has the following prohibitions, for example:
- Increased Sensitivity.
- Intolerance to the components.
- Epilepsy (one of the most common chronic neurological diseases of a person, manifested in the predisposition of the body to the sudden onset of convulsive attacks).
- Fever.
- Arterial hypertension (persistent increase in blood pressure).
With extreme caution, the medicine is taken during pregnancy.
"Cordiamin": instructions for use, price
Drops must be taken orally. Initially, the required single dose of the drug is dissolved in water.
Adults are advised to take up to one hundred and eighty drops per day.
In pediatrics, children from ten years of age are prescribed ten drops of Cordiaminum once a day. The drug has a low cost, within 200 rubles.
The duration of the course depends on the condition of the patient and the speed of his coming to health. For example, at low pressure, forty drops should be used to normalize performance. With edema of the bronchi and suppression of respiratory function, medication is carried out for several days to completely restore airway patency.
If suffocation occurs in children, the patient should be given drops as soon as possible so that the patient does not suffocate (according to the instructions for use). Cordiamine tablets do not exist.
Can I use the drug during pregnancy?
Currently, there is no reliable information regarding the safety of the action of the existing microelement on the intrauterine development of the baby. Since vasoconstriction is carried out against the background of the use of drops, it is important for women to use the drug with extreme caution during pregnancy. Frequent intake of the drug can lead to a constant narrowing of the vessels of the placenta, as a result of which the future baby does not receive the necessary amount of oxygen, which can adversely affect its development.
The use of drops during lactation should be discussed with a medical professional.
Side effects
Subject to the doctor's prescriptions, the drug is remarkably tolerated by patients. In people with increased sensitivity to trace elements "Cordiamine", a number of negative reactions may occur:
- irritability;
- anxiety;
- hyperemia of the face;
- migraine;
- nausea;
- impaired heart rate;
- allergy;
- hives.
Overdose
When ingestion of increased doses of "Cordiamine" inside, convulsions that remotely resemble epilepsy may occur. If seizures occur, a person needs to undergo complex therapy.
Interaction
"Cordiamine" is not recommended for people to use with ascorbic acid, since such a combination is unacceptable.
Under the influence of the drug, the pharmacological effect of antidepressants increases, which is important to remember when prescribing such drugs.
A medication can lower the effects of tranquilizers and analgesics when taken together.
Features
The drug can be taken in pediatrics in newborn babies with symptoms of asphyxia as a result of birth trauma, according to the instructions for use of Cordiamine. According to reviews, it is known that the dosage of drops in such cases is determined by a neonatologist.
Analogs
Substitute drugs are:
- Cordimide.
- Apilak.
- "Securinine nitrate."
- Gutron.
- "Dopamine Solway."
- Niketamide.
- Cortineff.
- "Caffeine".
- "Cofetamine."
- "Shave."
- "Etymizole".
- "Noradrenaline Agetan."
- "Ringer's solution."
- Estecor.
- "Armanor".
When changing "Cordiamine" one of the listed drugs, the patient should consult a medical specialist.
Cofetamine
The drug is considered a complex drug, the effect of which is due to the properties of its trace elements. The active substance is caffeine. The main component has a stimulating effect on the nervous system, as well as on the cerebral cortex and respiratory center, with the help of which physical performance is enhanced, fatigue and drowsiness are eliminated. In addition, caffeine increases heart rate by increasing blood pressure in hypotension.
When using the drug, sixty-two percent of the substance is absorbed from the stomach and intestines. Within two hours, its maximum content in the blood is achieved. Protein binding is ninety-eight percent.
The active substance is exchanged in the liver, as a result of which active metabolic products arise. Excretion of the main component is carried out, as a rule, with bile, in two stages. The elimination half-life varies from three to twenty hours.
Prolonged use of "Cofetamine" leads to addiction, as well as weakness in the legs, Lerish syndrome. The cost of the drug is 200 rubles.
Cortineff
The medication has a glucocorticoid and mineralocorticoid effect. Cortineff is dispensed from the pharmacy in the form of tablets for oral use.
The drug is a synthetic hormone of the adrenal cortex, which has a high mineralocorticoid activity. When compared with hydrocortisone, the effect of flucrocortisone is one hundred times higher, and the anti-inflammatory effect is only fifteen times.
The drug enhances the excretion of hydrogen and potassium ions, increases the reverse absorption of water and sodium in the renal tubules. When using the drug "Kortineff" in dosages that exceed the recommended pharmacological, inhibition of the activity of the adrenal cortex and thymus gland may occur.
The medication contributes to the deposition of the polysaccharide in the liver, and with a deficiency leads to a negative nitrogen balance. The cost of the drug is 120 rubles.
Gutron
The drug has a vasoconstrictive, hypertensive effect. In addition, Gutron has an activating effect on alpha-adrenergic receptors.
The drug is available in two forms:
In tablet form, Gutron is dispensed from drugstores in blisters, in a total of twenty capsules.
In the form of drops, the drug is sold in bottles of ten, twenty and twenty-five milliliters. The drug is an analogue of Cordiamine.
According to the instructions for use, it is known that the use of Gutron during pregnancy and breastfeeding is allowed after the approval of a medical specialist.
In addition, the medicine is subject to mandatory adjustment for severe diseases of the heart and blood vessels, as well as for violation of heart contractions and kidney damage. In this case, you need to carefully determine the dosage for the treatment of hypotension with changing weather. Long-term use of the drug should be accompanied by a clear control of the functioning of the kidneys. In addition, the study of the kidneys must be done at the end of treatment.
Storage conditions
Drops can be purchased at any pharmacy without a prescription. Keep the drug away from children. The optimum temperature should not be higher than twenty-five degrees (according to the instructions for use). According to reviews, the price of "Cordiamine" varies from 110 to 200 rubles.