"Nitroglycerin" tablets 0.0005 contain the active substance under the same name, with its content in each tablet of the drug - 0.5 milligrams. As auxiliary substances are used: microcrystalline cellulose, magnesium stearate, lactose, croscarmellose sodium, povidone ...
As the name of this publication shows, the tablets "Nitroglycerin" application instruction refers to cardiovascular drugs from the pharmacotherapeutic group cardiological agents. First of all, it should be said that this drug is effective in stopping angina attacks, which is the main indication for treatment with Nitroglycerin.
Instructions for use of this medication also include the following indications for its appointment:
- As part of complex therapy for acute left ventricular failure.
- Also in combination with other therapeutic treatment for acute myocardial infarction.
- With vasospastic angina pectoris.
Describing the pharmacological effect of the active substance nitroglycerin, the instructions for use call it a peripheral vasodilator, which predominantly affects the venous system. The effect of the drug is mainly due to such a factor as a decrease in preload (peripheral veins expand, blood flow to the atrium (right) decreases).
Reduces due to the action of "Nitroglycerin" and the total peripheral vascular resistance - afterload. Thus, myocardial oxygen demand is reduced. The drug provokes a central inhibitory effect against sympathetic vascular tone, by inhibiting the component of the vessels that forms the pain syndrome. With all of the above, due to the use of Nitroglycerin, meningeal vessels expand.
It is a consequence of the last effect of the drug that the occurrence of headache is explained. Sublingual (sublingual) tablets "Nitroglycerin", the instructions for use are called a remedy that relieves attacks of angina pectoris, literally within a minute - 90 seconds.
The absorption of the described drug from the surface of the mucosa occurs completely and quickly. The sublingual (sublingual) use of tablets of this drug provides almost instant penetration of the active substance into the circulatory system of the victim.
In the described drug - tablets "Nitroglycerin" - contraindications - this is, first of all, hypersensitivity to similar drugs, to nitrates. Also, this drug is not prescribed for isolated mitral stenosis, cardiac tamponade. Other contraindications to treatment with "Nitroglycerin":
- Pulmonary edema of toxic origin.
- Hemorrhagic stroke.
- Head injuries due to which the patient has recently been treated.
- Severe forms of anemic pathologies.
- Hyperthyroidism
- Closed-angle glaucoma in the presence of intraocular pressure.
- Collapse.
- Arterial hypotension (blood pressure matters)
- Simultaneous adoption with Viagra is not allowed.
- Pregnancy and lactation (with caution).
- Severe forms of renal failure (with caution).
- The risk of methemoglobinemia in liver failure.
- Shock.
Both the danger and the safety of using the medicine by persons under the age of eighteen have not been established.
Among the side effects recorded as a result of taking sublingual tablets and other forms of Nitroglycerin, one should single out abdominal pains, dry mouth, anxiety states, headaches, which are more pronounced at the initial stage of therapy. There have also been cases of allergies, weakness, dizziness, lethargy, tachycardia, fever.
To minimize the possibility of side effects of the drug, it is recommended to carefully combine it with other drugs, especially those with a hypotensive effect, alcohol. You can not take several tablets at the same time.