Prices, possible replacements, reviews, instructions for the use of "Genferon", "Genferon Light" - all of these topics are extremely interesting to those to whom the doctor prescribed this drug. The product belongs to the class of combined, has a pronounced local anesthetic effect. "Genferon" fights harmful viruses, enhances the human immune status. The active components of the drug have an antioxidant effect. However, the benefit of using a pharmaceutical product will be only if you use it according to the instructions, in accordance with medical recommendations. Self-medication "Genferon" is prohibited.
Features of the drug
In the instructions for use "Genferon" 500 000 UNITS (and other options for release), the manufacturer indicates that the tool is combined. Its effectiveness is explained by the presence of several active compounds in the composition. Not only local effects are inherent in “Genferon” - the drug has a systemic effect on the patient's body.
One of the main substances that ensure the effectiveness of the drug is recombinant human interferon. Initially, a product manufactured by one of the varieties of bacteria is used, but the product is improved by genetic engineering methods - the human interferon gene is introduced into it.
The resulting product, as stated in the instructions for use of "Genferon Light", "Genferon", has a pronounced effect against viruses, prevents pathological proliferation processes. Interferon has an antibacterial effect. The substance strengthens the immune status of a person.
And if in more detail?
The popularity of “Genferon” in gynecology in the instructions for use is explained by the fact that the interferon, on which the medication is based, is able to activate some enzymes inside the cells. The same phenomenon explains the applicability of Genferon in other branches of medicine. Under the influence of interferon, those compounds are activated that can inhibit the reproduction of viral cells.
"Genferon" has an immunomodulating effect, expressed in increasing the strength of the immune response at the cellular level. Activation of the mediated defense reaction is observed. The response of the immune system when used according to the instructions of Genferon suppositories of 500,000 units and other forms of release of the drug can increase the strength of the immune system, which collides with viral cells, parasites that invade organic cells. The drug is effective in relation to cells transformed due to tumor processes.
Under the influence of the drug, natural killer cells of the cellular level are activated, lymphocytic differentiation, antibody production, and phagocytosis become more active. The activity of the system of macrophages and phagocytes, molecular expression increases. Against the background of such processes, the immune system more efficiently recognizes which cells are infected.
Theory and practice
In the instructions for the use of candles "Genferon Light", the drug "Genferon" the manufacturer mentions the activation of leukocytes under the influence of human interferon. The effect is observed in all tissues that form the mucous membranes of the human body. Consequently, the fight against foci of pathological changes is faster and more effective. Interferon stimulates the normalization of IgA production. The antimicrobial effect of “Genferon” is explained by mediated immune reactions, the strength of which increases under the influence of human interferon.
And what else?
In the instructions for use of "Genferon" (spray, suppositories - all forms of release of the drug), the manufacturer reports that taurine is in the medication. This substance normalizes metabolism, stimulates regenerative processes, stabilizes cell membranes and enhances a person's immune status. Taurine is one of the powerful antioxidants that reacts with active oxygen molecules, the excess of which can cause illness. Due to the presence of taurine in the composition of the drug, interferon remains active for longer. It is taurine that provides Genferon with a long-lasting and strong therapeutic effect.
Another important substance mentioned in the instructions for use of "Genferon" is benzocaine. The compound has a pronounced local effect, relieves pain in the injection area. Under the influence of anestezin, membrane permeability to sodium ions decreases. At the same time, calcium charged particles are released from the receptors, which means that nerve impulses stop and cannot penetrate further than the generation area. Under the influence of benzocaine, the occurrence of a pain impulse, its conduction, is impossible. The action is strictly local. The inability of a substance to penetrate into the circulatory system and affect the body systemically is proven.
Drug kinetics
The use of Genferon suppositories according to the instructions in gynecology, pediatrics, and other areas of medicine has proved to be an excellent effect: tests have shown that the bioavailability when introducing suppositories into the rectum is extremely high, exceeding 80%. This allows you to achieve a strong local and pronounced systemic effect of interferon, affecting the human immune system.
Suppositories for women can be used not only rectally, but also injected into the vagina. In the instructions for the use of suppositories "Genferon" it is mentioned that this method of use allows to achieve an increased content of active components in the infectious focus, while the drug shows the most striking effect on the cells of the mucous membranes of the reproductive system. This allows you to slow down proliferation. Intravaginally administered suppositories "Genferon" have a pronounced effect against microbes and viruses. At the same time, there is minimal systemic effect, since the mucous membrane of the reproductive female system practically does not absorb active substances, which means that they cannot penetrate the bloodstream.
The maximum concentration in the plasma component of the blood is observed on average 5 hours after using the medication. In the instructions for the use of Genferon suppositories, the manufacturer mentions that the elimination of active compounds is provided by the kidneys. The half-life is from half a day, therefore, the optimal format for using the drug is twice daily.
What's on sale?
Most often, users are interested in instructions for the use of "Genferon" in the form of candles, since this is the format that is written out in most cases. The drug for rectal use is based on interferon, contains taurine and benzocaine. As additional compounds, solid fat and acids, sodium compounds, water, macrogol, dextran, emulsifier are used. Such a set of components provides shelf life and high efficiency of the product.
One package contains 5-10 suppositories "Genferon", instructions for use.
The manufacturer warns that the drug must be prescribed very carefully to allergy sufferers, people suffering an exacerbation of an autoimmune disease.
Also on sale is the spray "Genferon Light." Instructions for use for children under fourteen years of age, this format is contraindicated. You can not use it with nosebleeds. In addition to the main components in the composition of the spray there are sodium compounds, water, peppermint oil, potassium components.
The nuances of using
In the instructions for use of "Genferon", the manufacturer pays special attention to the fact that the best treatment result is achievable if the medication is combined with other medicines. This is especially true if urogenital infectious diseases are detected. "Genferon" goes well with antimicrobials and antibiotics.
Under the influence of anticholinesterase, non-narcotic painkillers, the strength of the effect of benzocaine increases. This component of the medication in question inhibits sulfonamides, making them less effective against bacterial invasion.
At the moment, there are no known cases of excessive use of Genferon.
How to use?
The appointment of candles is the doctor's responsibility. Prescribing the drug, the doctor will explain how often to administer it, how to do it correctly, and also pay attention to the instructions for use of "Genferon". Suppositories for children and adults can be used rectally. In gynecology, vaginal use is common.
Women who have identified foci of inflammation, infectious processes in the urogenital tract, are shown to use one candle in the vagina or intestinal tract twice daily. The dosage, option for the release of suppositories will be recommended by the doctor, assessing the severity of the disease, especially the causative agent that caused it. The duration of the course is 10 days. If the disease is prolonged, you can use the medication three times a week for a candle. In this format, the course can reach a quarter of a year.
If the activity of the foci of inflammation and infection is high, the area of ​​localization is the vagina, “Genferon” can be used locally by a candle in the morning, and the second candle can be administered rectally in the evening. In the intestinal tract, a twice more concentrated drug is used. At the same time, candles containing antimicrobial or antifungal components are placed in the vagina at night.
Special occasion
It is allowed to use Genferon suppositories for the treatment of pregnant women. During gestation, the drug is indicated for foci of inflammation, infection in the urogenital tract. The main objective of the course is to stimulate local immune defense. The medicine is allowed from the 13th week of the term to the 40th. Twice a day they use Genferon, introducing one candle with a dosage of 250,000 units in one procedure. The duration of the course is 10 days.
Men “Genferon” is indicated for inflammation, infections in the urogenital tract. The drug is injected into the intestinal tract. Recommended dosages are 500,000 units and twice as much. The doctor chooses a specific option, assessing the severity of the course of the disease. Course duration - one and a half weeks, frequency of use - twice every day.
Note!
In acute bronchitis, the use of “Genferon” candles is indicated for adults, and for children - “Genferon Light” candles. Instructions for use draws attention to the fact that it is allowed to use the drug at different ages. If necessary, treatment of very young children should contact a pediatrician for the selection of the optimal program. With bronchitis, the use of the drug as an element of a comprehensive therapeutic course is indicated - only Genferon alone can not cope with the disease. Usually use suppositories twice a day for at least five consecutive days. The dose of a single procedure should be prescribed by a doctor.
With cystitis occurring in a chronic form, prone to relapse, adult patients “Genferon” is prescribed as an element of a comprehensive treatment program. During exacerbations, candles with a maximum content of active substances are used, injecting them twice a day into the intestine. The duration of the program is one and a half weeks. Antimicrobials are taken at the same time. For the prevention of relapse "Genferon" is used for a candle in the intestines for 40 days in a row. Use the maximum release option - 1,000,000 units.
Use cases: children
Instructions for use for children "Genferon" in certain forms of release can be used from infancy. A dosage of 125,000 units is considered safe - this format of suppositories is prescribed for babies up to the age of seven. From seven years and older, candles containing 250,000 units of active ingredients can be used.
For children, instructions for use "Genferon" is recommended as an element of the complex treatment of viral diseases (including acute respiratory viral infections). Twice a day, a candle is administered, maintaining half-daily intervals between the procedures. The duration of the drug is five days. If, at the end of such a course, the symptoms do not subside or become heavier, it is urgent to get an appointment with a qualified doctor. In some cases, the doctor recommends a five-day interval and undergo repeated treatment.
In case of chronic foci of viral activity, Genferon children are prescribed twice daily, observing breaks of 12 hours between procedures. At the same time, other means are used to stop inflammatory processes and infection. Course duration - one and a half weeks. Then, for another quarter of a year, one candle is used rectally every other day.
With foci of infection, inflammation in the urogenital tract, and in the acute form of the disease, children "Genferon" is prescribed twice a day for a candle ten-day program. At the same time, they undergo a specific course of treatment at the discretion of the doctor.
It is possible and impossible
It is not allowed to use Genferon if individual intolerance and hypersensitivity to any substances included in the composition of the drug are established. This applies both to the main active compounds and to additional components used by the manufacturer to stabilize the product and ensure its long shelf life.
In case of allergies, autoimmune disease in the acute stage, “Genferon” is prescribed only if possible to monitor the patient's condition, since such use is associated with a number of risks.
Genferon can be used as an element of a comprehensive treatment program for foci of inflammation and infection in the urogenital tract. The drug is often prescribed for herpes, localized in the reproductive system, infection with chlamydia, urea, mycoplasma, as well as candidiasis detected in the vagina and prone to relapse. You can use "Genferon" for infection with gardnerella, Trichomonas, HPV. Studies have shown the effectiveness of Genferon suppositories in case of uterine erosion, vaginosis due to bacterial invasion. The drug is prescribed for cervicitis, urethritis, prostatitis and a number of other diseases of the reproductive system, urinary tract.
You can use the medicine for acute bronchitis.
Important Nuances
You can use the drug in question while carrying a child. "Genferon" is allowed in the second and third part of the term. First, the doctor must analyze how great the benefits of such a therapeutic course are, evaluate all the possible risks associated with it, and inform the expectant mother about the dangers that can cause the use of a composition - a spray or suppositories. Only in the case when the obvious benefit is more significant than the potential risks, "Genferon" is prescribed, choosing a dosage so as not to harm the child.
To minimize the risk of re-urogenital infection, it is necessary to undergo a comprehensive therapeutic program at the same time as a regular sexual partner. You can use the medication during menstrual bleeding.
It was not possible to detect the ability of "Genferon" to influence the ability to concentrate, and therefore, during the treatment program it is allowed to drive vehicles, work with mechanisms.
Note!
"Genferon" is allowed for women bearing the fetus in the period 13-40 weeks. The drug is often prescribed as one of the means in the fight against HPV, herpetic viruses, cytomegalovirus, chlamydia, myco-, ureaplasma. "Genferon" is indicated during pregnancy with vaginosis.
Often the described conditions are accompanied by local burning, itching, unpleasant and even painful sensations in the inguinal region. To alleviate the condition of the patient is allowed to use "Genferon" at a dosage of 250,000 units. Clinical studies have proven that in this format of use in these weeks of pregnancy, the medication is safe.
There is currently no exact information about the possible dangers of using the drug in the first trimester of bearing a child.
Features of use by children
The possibilities of using Genferon in childhood cause some disagreement among specialists. The manufacturer in the instructions for the candles does not indicate age restrictions on the use, but many doctors are firmly convinced that for people under the age of seven it is not worth using the described tool. , « », – , «».
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