What is the drug "Estrofan"? Instructions, methods of use, the composition of the medication will be indicated below. You will also learn about for whom this remedy is prescribed and for what indications.
Form, composition
The drug "Estrofan", the instructions for use of which is in a cardboard box, goes on sale in the form of an injection solution. The active component of this agent is cloprostenol, and the auxiliary components are citric acid, sodium hydroxide, chlorcresol and water for injection.
In appearance, this medication is a clear solution without color and a pronounced odor. It is packaged in glass ampoules or glass bottles, which are corked with rubber stoppers and secured with aluminum caps.
Pharmacological properties
What features are characteristic for the drug "Estrofan"? Instructions for use in veterinary medicine say that this tool belongs to the pharmacological group of hormones and their antagonists.
Cloprostenol is a hormone prostaglandin PHF2a (synthetic). It is able to exert a luteolytic effect on the corpus luteum of the ovaries, as well as eliminate the inhibitory effect of progesterone on the hypothalamic-pituitary complex and promote the growth of follicles. Due to this effect, the substance in question increases the level of estrogen in the blood, causes manifestations of sexual hunting and ovulation of mature follicles. Also, cloprostenol enhances uterine contractions.
Kinetics means
What kinetic properties does Estrofan solution have? Instructions for use in veterinary medicine claims that in animals the main substance of this drug is metabolized quite quickly, after which it is excreted along with urine during the day.
By the degree of its effect on a living organism, Estrofan belongs to moderately hazardous drugs (hazard class 3).
Indications for appointment
Instructions for use of "Estrofan" (the composition of the drug was indicated above) states that this tool causes synchronization and estrus in mares, ordinary and spring cows. It is also used to induce farrowing of sows.
In small and cattle, this drug treats abnormalities in the ovaries, post-service and postpartum anestrus (including silent estrus, impaired periodicity of the cycle, persistent corpus luteum, anovulation cycle, luteal cyst), as well as endometritis, post-peruperal diseases of the uterus, its suppuration interruption of pathological and normal pregnancy (in the first half).
What are the other uses of Estrofan? Instructions for use in veterinary medicine reports that this medicine works well in combination therapy of follicular cysts.
Dosage and administration
Instructions for the use of the Estrofan veterinary drug states that cattle is administered intramuscularly to cattle. To synchronize estrus, it is prescribed 2 ml twice a day with an interval of ten days.
The first dose of the drug is used in any phase of the cycle. On the eleventh day after the first injection, a double dosage is administered, and on the 14th day artificial insemination is carried out, followed by repetition on the fifteenth day.
Before each use of the injection solution for synchronization in a pet, a thorough examination of the genitals should be performed.
For the treatment of ovarian disorders, the drug in question is administered in 2 ml. In this case, artificial insemination is carried out at the first estrus. If it does not occur, then the medication is reused in a dosage of 2 ml, on the eleventh day after the first injection, followed by artificial insemination after 72-75 hours.
In order to treat follicular cysts, Estrofan solution is administered once in an amount of 2 ml, not earlier than on the tenth day after administration of LHRH or HCG and the establishment of a positive ovarian response. In this case, estrus should occur on the third day after the administration of the drug.
Treatment of post-peruperal uterine diseases is carried out by introducing 2 ml of the drug. If required, then such therapy is supplemented with intrauterine application of drugs (washing or in the form of a foam). In this case, insemination (artificial) is carried out on day 14, and on 15 - it is repeated.
Termination of pregnancy in domestic animals is treated with the introduction of 2 ml of the drug. Subsequent care depends on their condition.
A single dose of the sow agent in question is 0.7 ml. At the same time, it is introduced from the 111th day of pregnancy. Most often, induced farrow occurs 39 hours after administration of the drug.
Personal Prevention
Now you know how to use the Estrofan medication. Instructions for use in veterinary medicine have been described in detail above.
When working with this medication, all safety rules must be observed. After completing veterinary work, wash your hands and face thoroughly.
If the drug comes in contact with the optic membranes or skin, they should be immediately rinsed with plain water. Veterinarians with hypersensitivity to drug substances need to avoid direct contact with it.
If you develop an allergy or accidentally swallow a solution, you should immediately consult a doctor.
Empty medicine vials cannot be used for domestic purposes. Such containers must be disposed of.
Reviews
Most reviews of the veterinary drug Estrofan are positive. Farmers claim that after using this product, their livestock has significantly decreased deaths due to internal diseases, as well as significantly increased fertility of young animals.
As for the shortcomings of this drug, then most people attribute its toxicity to humans to them. Therefore, injections should be given to animals only by experienced specialists, observing all safety and personal hygiene requirements.