Allergies in humans can occur in different ways. But most often, the hypersensitivity of the immune system is accompanied by symptoms such as pain in the eyes, urticaria, swelling, runny nose, cough, and sneezing. The listed manifestations bring a lot of discomfort to the patient. Therefore, people who regularly suffer from allergic reactions very often use drugs that can reduce the severity of such symptoms to a minimum. One of them is the medicine "Claridol". Instructions for use, photos, indications and form of release of the drug are presented below.
Description of the drug, its release form, packaging and composition
In what form are the drug in question produced? According to experts, this medicine can be found in such forms as:
- Claridol tablets. Instructions for use indicate that such a drug has a white color, a round flat shape, beveled edges, and also a fault line on one side.
The active ingredient in this medication is loratadine. In addition to this, the composition of this agent includes components in the form of anhydrous silicon dioxide, colloidal dioxide, microcrystalline cellulose, starch, purified talc, sodium methyl paraben, magnesium stearate, purified water and sodium starch glycolate.
On sale, this tool comes in blisters and cardboard boxes, respectively.
- Syrup "Claridol". Instructions for use states that this form of the drug is made in the form of a transparent orange liquid with a pleasant aroma and sweet taste.
Its active ingredient is loratadine. The syrup also contains sodium sucrose, sodium propyl paraben, citric acid, propylene glycol, sorbitol solution, sodium benzoate, sodium saccharin, disodium edetate, mixed fruit flavor, methyl paraben, dye "sunny sunset", purified water and American ice cream.
You can buy this medicine in dark glass bottles.
Drug action
What is the medicine "Claridol"? Instructions for use, reviews indicate that it is a blocker of H1-histamine receptors, which has a long-lasting effect. It prevents the development of allergies, and also releases C4 leukotriene and histamine from mast cells.
It is impossible not to say that this drug has antiexudative, antiallergic and antipruritic effects. It prevents the development of tissue edema, relieves smooth muscle spasms and reduces capillary permeability.
This tool does not affect the central nervous system, psychomotor functions, mental abilities, ability to work and attention, and does not cause drowsiness or addiction, since it practically does not penetrate the BBB.
The antiallergic properties of this drug develop after half an hour and reach its maximum after 8-13 hours (the effect lasts for a day).
Kinetics of the drug
Is Claridol absorbed? The instruction for use claims that after oral administration it is fully and rapidly absorbed from the digestive tract. Eating food slows down the process of accumulation in the blood by one hour when taking pills and does not affect absorption by syrup.
The relationship of the drug with plasma proteins is 97.5%. It is metabolized in the liver with the formation of such an active derivative as descarboethoxyl loratadine.
The half-life of loratadine is 5-20 hours (it is excreted along with urine and bile).
Indications for use of the drug
When is the patient prescribed Claridol? Instructions for use (syrup and tablets have the same indications) states that this remedy is effective in:
- hay fever;
- allergic reactions to insect bites;
- rhinitis year-round;
- pseudo-allergic reactions;
- rhinitis seasonal allergic;
- allergic conjunctivitis;
- dermatoses of allergic itching;
- urticaria (including chronic idiopathic form of the disease);
- itching of various origins;
- Quincke's edema.
Contraindications
In what cases should not use the drug "Claridol"? Instructions for use (for children under two years of age, this remedy is not prescribed) indicates such contraindications as:
- pregnancy;
- hypersensitivity;
- breast-feeding.
With extreme caution, this medication should be recommended to patients with impaired liver function (including liver failure).
The drug "Claridol": instructions for use
From what this remedy is prescribed, we described above. How should it be taken? According to experts, this tool is used only orally.
For elderly and adult patients, as well as children from 12 years of age, the medication is prescribed 10 mg once a day.
Children 2-12 years old with a body weight of less than 30 kg are recommended to take 5 mg of the drug once a day.
As for children 2-12 years old with a body weight of more than 30 kg, they are given 10 mg of the drug once.
Prescribing this medication to children under 2 years of age is highly not recommended.
For people with impaired liver function, the described drug is prescribed in an initial dosage of 5 mg per day.
Side effects after taking the medication
How is Claridol tolerated by patients? Instructions for use states that the use of this medication may cause the following reactions:
- headaches, vomiting, dizziness, impaired liver function, drowsiness;
- fatigue, palpitations, tachycardia;
- cough, allergic reactions (including rash and anaphylaxis), alopecia
- dry mouth, irritability, nausea, lethargy, gastritis.
Drug interaction
When combining the drug in question with “Cimetidine”, “Ketoconazole” or “Erythromycin”, an increase in the concentration of its active substance in the blood is possible, which has no effect on the ECG and has no clinical value.
Microsomal oxidation inducers such as barbiturates, phenytoin, rifampicin, zixorin, tricyclic antidepressants, phenylbutazone, as well as ethanol, decrease the effectiveness of loratadine.
Patient Reviews
Consumers claim that the drug "Claridol" is a very effective anti-allergic agent. It quickly eliminates such unpleasant symptoms as sneezing, itching, coughing and others, helping to improve the patient's condition.
The disadvantages of this medication include the presence of many side effects, as well as the inability to prescribe to pregnant women and nursing mothers.