In the article, we consider the instructions for use with Streptocide.
It is an antimicrobial drug, which is one of the chemotherapeutic drugs with bacteriostatic effect in relation to pneumococci, E. coli, meningococci, gonococci, streptococci and other bacteria.
This article will discuss the features of the use of "Streptocide", dosages, available analogues and the real reviews of doctors and patients who used it.
Forms of drug release
The drug is produced in the following forms:
- White tablets, which contain 300 and 500 milligrams of streptocide, ten pieces per pack.
- Ointment "Streptocide". The instruction reports that the concentration of the active substance in it is different 5 and 10% based on petroleum jelly. The drug comes in tubes of 50, 30 or 25 grams.
- 5% suspension, which contains five grams of streptocide, 0.5 grams of thymol, 69.75 grams of distilled water, 20 grams of emulsifier.
- 5% liniment, which contains 5 grams of streptocide, 3.1 grams of animal fat, 57.9 grams of lime water, 34 grams of fish oil, cans of 30 or 25 grams.
The composition of the drug and the features of influence
According to the instructions for Streptocide, the active component of the drug is sulfanilamide, a proven and old chemotherapeutic antimicrobial agent. The medicine changes the procedure for the formation of vitamin B9 (folic) and dihydrofolic acid. In this, it is similar to other antibiotics from among sulfonamides. The streptocidal molecule has a structure that is similar in structure to paraaminobenzoic acid. Being an antagonist of PABA (its pair is aminobenzoic acid), it damages the chain of metabolic reactions of bacteria and stops metabolic processes in cells. This contributes to the bactericidal effect. As indicated by the instruction, the soluble Streptocid is a sulfanilamide that is fast-acting.
White “Streptocid” is used orally, absorbed at high speed. The peak content in blood plasma occurs after one and a half hours, the blood-brain barrier overcomes after four hours. The powder is metabolized in the same way. The elimination half-life is approximately equal to eight hours. For excretion, the main burden falls on the kidneys, they excrete more than 95% of the metabolites.
When is a medication used?
In accordance with the instructions for Streptocide, the indications for use are infectious diseases with a pronounced process of inflammation. White “Streptocide” (both powder and in other forms) is used for:
- diseases of the mucous membranes and skin: ulcers, wounds and pressure sores;
- inflammatory process of the bladder and diseases of the excretory system;
- enterocolitis and prick.
The drug is used for angina in the form of a powder diluted with water, which needs to be gargled. In addition, the drug is used against protozoa, including malaria and toxoplasmosis pathogens.
The drug in a slightly alkaline environment exhibits an increased degree of activity. Very low absorption when applying liniment or ointment through intact skin.
Although the drug has antimicrobial activity, Streptocide is used in rare cases from acne in rare cases, but this is possible. Affected areas on the face should be treated with a cotton pad, which is wetted in the solution. For this, a soluble Streptocide is taken. The instructions for use confirm this. An ointment or liniment is applied to the face. However, it is better to replace the remedy for acne with a safe and reliable drug - zinc ointment.
All sulfonamides, including the white Streptocide, are characterized by limited use. This is due to their lack of effectiveness against most infectious pathogens, many side effects and the inability to use it during pregnancy. For example, it is inappropriate to use in the treatment of anaerobic infections, which are caused by clostridia, and diseases caused by Pseudomonas aureginosa and enterococci. It does not act on fungi, and is also not used in getting rid of fungal infections.
This drug was almost completely replaced by modern antibiotics. It is also important that the majority of virulent strains acquired resistance over time to the bacteriostatic effect of the active substance, in particular this applies to infectious hospital pathogens.
The instructions for the Streptocid tablets will be discussed below.
Allergoproba drug
An allergy test must first be done to determine the presence of a hypersensitivity reaction to the drug. For this purpose, a scratch should be made on the inner surface of the wrist, anointed with a small layer of ointment on top or sprinkled with powder. If after fifteen minutes there is no edema, redness, general malaise of the patient, an allergy test is passed. During pregnancy, the drug cannot be used.
In addition, it is necessary to determine the degree of resistance of pathogenic flora. Spend this laboratory methods. Therapy is advisable if the microorganisms are moderately stable or sensitive to the active substance.
After that, they begin to be treated, while choosing a convenient form for themselves.
Streptocide tablets: instructions for use
The instruction reports that the tablets are made in a blister of ten pieces, the concentration of the active substance is 300 or 500 milligrams.
The most convenient to use is this form. The tablets are crushed into powder and can be taken orally in this form.
You need to drink it with water, use the product 5-6 times a day for 500 milligrams. The maximum daily dosage for an adult patient is seven grams. Single - five grams.
The following is a brief instruction for use with Streptocide powder.
Powder
Powder or soluble Streptocide is available in small bags of two grams. This form can be used externally as applications for the treatment of skin and mucous membranes. Inside the wound, sterile soluble Streptocide (powder) can be poured in an amount of five to fifteen grams. Dressings need to be done in 1-2 days.
Also, according to the instructions, Streptocid powder can be drunk if dissolved in boiled water. In this case, the dosage is the same as with the use of tablets.
Liniment
A form such as liniment is in the tube, which contains fifty grams of the active component with a concentration of 5%.
The instructions for the streptocid liniment are simple and straightforward. Since it is liquid, in some cases this makes the treatment of the epidermis uncomfortable, in which case an ointment is better.
Streptocide ointment
In accordance with the instructions for use, Streptocid ointment is produced in tubes of thirty grams. The concentration of streptocide is equal to ten percent. Sometimes ointment is found in dark glass or plastic jars of 15, 25 or 20 grams.
Ointment or liniment is applied topically over the wound. Both forms must be applied with a thin layer and not rubbed. It is also allowed to use Streptocid ointment under a gauze dressing.
It is forbidden to constantly use the drug for more than two weeks. Sometimes it is allowed to use the medicine once a day on a small area of the skin, however, in no case should it be applied to the face.
Before and after using the medication, you need to wash your hands well.
Contraindications
What else can you learn from the instructions? "Streptocide" can not be used in the following cases: with severe kidney or liver failure, porphyria, anemia, congenital deficiency of glucose-6-phosphate dehydrogenase, azotemia, pregnancy, as well as hypersensitivity to the ingredients in the composition, breastfeeding. "Streptocide" is forbidden to treat newborns, since it contributes to the appearance of nuclear jaundice. The medicine in the form of tablets is contraindicated until the age of three.
Interaction with other drugs
Medicines that suppress hematopoiesis can enhance the similar effect of Streptocide. The instructions for use confirm this.
If a large piece of skin is processed, the drug can increase the side effects of hematotoxic drugs that adversely affect the blood system. When treating with “Streptocide” after the skin has been lubricated with “Novocain”, the therapeutic effect of the drug is reduced, and therefore it is recommended to observe at least a half-hour break between the uses of these funds.
It is undesirable to combine the use of Streptocide and medicines that contain such active substances as phenobarbital, caffeine and phenylephrine.
Side effects and overdose
According to the instructions to "Streptocide", when using the drug, side effects are not excluded. This can be a severe headache, slight dizziness, vomiting, nausea, or a vomiting reflex. In some patients, severe allergic manifestations, disturbances in the activity of the heart and blood vessels, which were observed in the form of tachycardia, were also noted.
In case of drug overdose, it is necessary to rinse the stomach with a 2% solution of sodium bicarbonate and activated carbon or other enterosorbents. In case of an overdose, vomiting, nausea, dizziness, paresthesia, headache, tachycardia, cyanosis, renal shock, hematuria, diarrhea, fever, and sweating may occur.
Analogs
“Streptocide” has such structural analogues in the active substance as “Sulfanilamide”, “Osarcid” and “Streptonitol”.
Another analogue is Sunoref ointment, which contains streptocide, norsulfazole, camphor, eucalyptus oil, ephedrine hydrochloride, sulfadimezin. It is used locally in the treatment of chronic and acute rhinitis.
The opinion of experts
Doctors' opinions about this drug are mostly neutral or negative. They say that “Streptocide” can dry a wound on the surface of a child’s skin, but this medicine is not at all what it used to be. “Streptocide” tablets, which were sold in the USSR, are difficult to replace with anything. Experts say that he did not dry the wound, for example, with burns, but covered its surface with a hard crust, giving a feeling of discomfort.
Doctors believe that for your peace of mind, you can buy one pack of medicine so that it is at hand at home. But the quality of the current drug is still dubious. At the institutes, this substance has not been studied for about forty years, so it is difficult to say for what purpose it can be used.
Patient Reviews
Patient reviews about the drug, on the contrary, are mostly positive. "Streptocide" is a universal remedy with a very wide scope. He is proven and old, helps in many cases. People say that from childhood they took it at the first symptoms of a sore throat, and he really coped with the pathology. The tablet should be held in the mouth until dissolved and a little swallowed saliva. They also advise crushing it and blowing it in the throat, since this is the most effective method.
Also, the drug is used in the treatment of burns and fresh wounds. The damaged area is washed, sprinkled with powder, covered with a gauze cloth and bandaged. The tool is effective and inexpensive.
Many patients say that they have “Streptocid” in a first-aid kit in a ground state. It not only tightens the affected skin area, but also has excellent antiseptic properties. People like that, getting into the wound, the powder first creates a kind of barrier to external irritants. For example, when salt is cut, it is not so felt after treatment with the drug. Then the wound turns into a dry crust, and it also passes very quickly.
When used for sore throat, discomfort was noted due to the taste of the medicine. In the treatment of children, this will cause certain difficulties, since small patients will most likely not agree to take a second pill. Adults can endure.
Also, tablets are taken for inflammatory processes in the genitals of a woman and the bladder, for five days a course of 3-5 tablets. "Streptocide" allows you to achieve an excellent result. Among the advantages, its cheapness is also noted.
It is noted that the drug has long been banned for admission to the European Union, since it negatively affects the hematopoietic system.
There are also negative reviews, which say that the desired result was not achieved, the pain only intensified.
Many people considered Streptocide their whole life a wonderful antiseptic; it was successfully used by the whole family in accordance with the evidence. However, then they learned that the drug is among the antibiotics (more precisely, it is an antiparasitic and antimicrobial agent), and therefore they began to use it more carefully for sore throats, despite the fact that it copes well with inflammation, including with purulent.