Medication “Lomilan” is an antihistamine medication of systemic effects, which is a blocker of H1-histamine receptors. It has an antipruritic, antiallergic, antiexudative effect.
Reviews about Lomilan are abundant.
Composition and form of release
The drug is made in tablets and syrups. The tablets have a flat, round shape, chamfer, dividing at risk, white color. They are packaged in 10 pieces in blisters and cardboard packs of 3, 2 or 1 blister. The suspension for oral administration is a homogeneous suspension of white color, in dark glass bottles, packaged in cardboard packaging of 1 pc., With a dosage spoon. A pack of medication also contains instructions for its use.
The tablets contain an active element - loratadine, and auxiliary components: gelatinized starch, corn starch, magnesium stearate. The oral suspension also contains the main substance - loratadine, and additional elements: citric acid monohydrate, polysorbate, sodium benzoate, sodium dihydrate citrate, crystalline white sugar, Avitzel RC 591 FMC, concentrated glycerol, propylene glycol, Wild Cherry flavoring, purified water.
According to reviews, Lomilan syrup is very popular with children.
pharmachologic effect
Lomilan is a histamine H1 receptor blocker for systemic use. It has anti-allergic, antipruritic and anti-exudative properties, does not affect the central nervous system, does not cause symptoms of addiction. This drug helps to reduce the permeability of capillary vessels, prevents the occurrence of swelling of the tissues, eliminates spasms of smooth muscles. The therapeutic effect begins about 30 minutes after application, but the maximum effectiveness occurs after 7-13 hours and lasts throughout the day.
Pharmacokinetic properties
The substance after oral administration in full is rapidly absorbed from the digestive organs. After a single dose, the maximum concentration is reached in 1 hour. In the presence of food in the stomach, absorption slows down somewhat. Binding to plasma proteins is more than 96%. This active substance does not penetrate the blood-brain barrier. The processes of its metabolism occur in the liver, with the formation of descarboethoxyl loratadine in the form of an active metabolite. The half-life of the active element is 8 hours, and it is excreted in the bile and urine. With alcoholism and in old age, metabolic processes lengthen. The pharmacokinetic parameters during hemodialysis and chronic renal failure are almost not violated.
This is what the instruction to Lomilan says. Reviews about the drug are mostly positive.
Indications for appointment
Tablets and syrups of a medication are used in the treatment and prevention of the following pathologies:
- seasonal and year-round allergic inflammation of the mucous membrane of the nasal cavity (rhinitis);
- allergic inflammation of the mucous membranes of the eyes (conjunctivitis);
- skin pathological processes of allergic etiology (including idiopathic urticaria in a chronic course);
- allergy insect and animal bites;
- pseudo-allergic phenomena.
Contraindications
It is better to familiarize yourself with the reviews about Lomilan from allergies in advance.
Absolute contraindications for taking this medication are:
- lactose intolerance,
- lack of lactase;
- fructose intolerance ;
- sucrose or isomaltase deficiency;
- pregnancy, lactation;
- age up to 3 years;
- intolerance to the components of the drug.
Relative contraindications can be considered severe renal or hepatic insufficiency.
Dosage and administration
The medication must be taken orally with milk. Simultaneous intake with food is allowed. Chew tablets if necessary.
Adults and children over 12 years of age are prescribed 1 tablet once a day, for children weighing more than 30 kg the dosage is the same. Children after 3 years old weighing less than 30 kg - half a pill 1 time per day. According to reviews, Lomilan tablets are generally well tolerated.
Syrup for adult patients and children after 12 years of age is prescribed in the amount of two dosage spoons 1 time per day. For children 2-12 years old, whose weight is above 30 kg, the dose corresponds to an adult, with a weight of less than 30 kg it is 1 dosage spoon.
Children under 12 years of age are preferable to prescribe this drug in the form of a suspension. Patients with impaired hepatic function should reduce the daily dosage of the drug. The duration of therapy depends on the duration of the symptoms of the pathological process. In the absence of improvement within 3 days of treatment, it is necessary to discuss the effectiveness of the drug with the attending specialist.
Side effects
According to reviews, Lomilan can provoke such negative reactions as:
- nervousness;
- cephalgia;
- sedation;
- dry mouth
- drowsiness;
- bouts of nausea;
- fatigue;
- gastritis;
- alopecia;
- skin rashes;
- impaired liver function;
- anaphylactic reactions.
Overdose symptoms
The main signs of an overdose of this medication are: headache, drowsiness, increased heartbeat (may last a long period of time). For therapeutic purposes, it is necessary to remove the drug from the digestive tract as soon as possible and, if possible, reduce its absorption (by taking activated charcoal, washing the stomach). There is currently no specific antidote for the main active element of this drug in medicine.
Two days before the implementation of skin allergy tests, the use of the pharmacological agent "Lomilan" should be discontinued, since it can change the results of such laboratory tests.
Influence on the ability to drive vehicles and mechanisms
Data on the effect of the drug (when used in recommended dosages) on the concentration of attention and the speed of mental and motor reactions are not available. However, patients should be careful when exceeding the dose or when unusual reactions occur while engaging in hazardous activities.
Antihistamine Lomilan is not used during pregnancy and lactation.
In childhood
The drug is approved for use in childhood, but the main contraindication for the appointment of the suspension is the age of the child up to 2 years, tablets - up to 3 years. According to reviews, Lomilan for children is effective and safe.
Drug interaction
Medicines such as Cimetidine and Ketoconazole can increase the concentration of the main element of the Lomilan drug in the blood. With the joint treatment with microsomal oxidation inducers (Rifampicin, ethanol, barbiturates, Phenytoin, tricyclic antidepressants), the effectiveness of this substance decreases.
Analogs
The list of analogues of this medication includes the following:
- Loratadine
- "Loratadin-Akrikhin";
- "Loratadin Teva";
- Loridine
- Lorahexal.
The replacement should be selected by the doctor.
Reviews about "Lomilan"
Today, almost 40% of the world's population suffer from allergies, and this figure is increasing annually. Therefore, medicines for this disease are always quite relevant.
The medicine "Lomilan", according to reviews, is in high demand among patients. They note that this is a fairly modern and safe drug that does not cause drowsiness, loss of strength and many other negative manifestations, unlike other antihistamines. It helps to normalize the condition, eliminates the symptoms of allergic rhinitis, nasal congestion, skin rashes due to exposure to allergens. Great for treating children. In addition, according to patients, this drug is an inexpensive and affordable tool, which can also be attributed to its advantages.
We reviewed the instructions for use and reviews of Lomilan.