In the article, we consider the instructions for use with Andipal, reviews and analogues.
The tool is included in the group of combined drugs that have an antispasmodic, analgesic and vasodilating effect. It relieves painful sensations associated with smooth muscle spasms with a high degree of effectiveness. In addition, it has a weak antihypertensive effect, slightly lowering blood pressure. It is a common drug that is often prescribed as part of complex therapy for hypertension.
Reviews for Andipal are presented below.
Description
The drug belongs to the combined clinical and pharmacological group and has an analgesic, antispasmodic, sedative and vasodilating effect.
Andipal is available in pharmacies without a doctor’s prescription and is an inexpensive drug. On average, the cost of one package is about 30-40 rubles.
Tablets are produced in a flat-cylindrical form, have a yellowish or white tint. Packed in tablets of 10, 30 and 100 pieces.
Structure
The active ingredients of the drug are analgin or metamizole sodium, papaverine hydrochloride, bendazole and phenobarbital. In addition, a number of excipients are present in the tablets, such as starch, talc, steric acid, calcium sterate, etc.
The drug effectively dilates blood vessels, relieves spasm and anesthetizes, which is due to the active substances included in its composition.
Papaverine hydrochloride and bendazole have the ability to dilate peripheral vessels and reduce the high tone of the so-called smooth muscles. Sodium metamizole has an antipyretic and analgesic effect on the body.
“Andipal”, depending on the indications, is prescribed as an antispasmodic for violations in the vessels of the brain and periphery. Taking the drug causes a decrease in blood pressure, reduces total peripheral vascular resistance (OPSS) and normalizes collateral circulation. Phenobarbital as part of the drug allows you to enhance the action of other substances, and also has a mild calming effect on the nervous system.
Reviews on the use of Andipal are abundant.
Indications and contraindications
The instruction contains the following indications for its use:
- Pain syndrome that occurs against a background of spasm of the smooth muscles of the gastrointestinal tract, cerebral vessels and peripheral arteries.
- Arterial hypertension.
There are also a number of contraindications to taking the drug. Among them:
- Angle-closure glaucoma.
- Bowel obstruction.
- The child is under 8 years old.
- Enlarged prostate gland.
- Deficiency of the liver or kidneys of a pronounced type.
- High sensitivity of the body to the components of the drug.
- Glucose-6-phosphate dehydrogenase deficiency.
- The period of gestation and lactation.
- Severe angina pectoris, a decompensated form of chronic heart failure, tachyarrhythmia and other diseases associated with the blood and circulatory system.
Phenobarbital negatively affects the fetal development. Even in small doses, it can cause underdevelopment of the brain of an unformed child. In addition, the fetal nervous system falls under attack. The risk of having a baby with cerebral palsy is increasing. Therefore, the reception of Andipal during pregnancy is categorically prohibited. In most cases, the choice is the woman.
It is necessary to take into account the fact that most antihypertensive drugs can have teratogenic, that is, fatal effects on the fetus. Reviews about Andipal from pressure are contradictory.
Instruction manual
"Andipal" is prescribed for oral administration without chewing. The standard dosage is considered for an adult 1-2 tablets 2-3 times a day. The duration of admission should be no more than 10 days.
Before taking the drug, be sure to consult your doctor. Duration of admission can be adjusted depending on the nature of the disease and patient complaints. However, taking the drug for more than 10 consecutive days is not recommended.
The drug is prescribed at high pressure, that is, it acts hypotensively. With hypotension, its use is strictly prohibited, as this can lead to negative changes in the brain.
Side effects
According to reviews, Andipal can provoke a number of negative reactions. In particular, they include:
- Nausea followed by vomiting.
- Blood clotting disorder.
- Failure of the gastrointestinal tract.
- Decrease in the immune qualities of the body.
- The state of depression.
- General weakness.
- Impaired functioning of the liver system.
- Imperishable feeling of drowsiness.
- An allergic reaction to the components of the drug.
According to reviews of “Andipal”, side effects, as a rule, appear against the background of prolonged use.
If the dosage is exceeded, overdose symptoms may appear, such as:
- Dizziness.
- Increased sweating.
- Collapse.
If signs of an overdose are observed, it is urgent to rinse the stomach and take enterosorbent. In the future, symptomatic therapy is prescribed. This is confirmed by the instructions for use and reviews of Andipal.
Special recommendations
Andipal is not intended for long-term use. Tablets are used for symptomatic administration according to the patient's condition. If you need to take the drug for more than a week, then you need to monitor the condition of the liver and analyze the composition of the patient’s peripheral blood. If three days after the start of the administration, the therapeutic effect is not observed, it is necessary to refuse further administration and consult a doctor.
It is important to remember that Andipal is part of a group of narcotic analgesics. That is, it can affect psychomotor reactions. For this reason, you should refuse to drive the car for the treatment period. The presence of phenobarbital causes addiction to the drug over time. For children over 8 years of age, the drug should be taken only strictly in accordance with the doctor's prescription.
In combination with some drugs, the effect of Andipal increases. These medicines include:
- Beta-blockers - Anaprilin, Metoprolol, etc.
- Diuretics - "Lasix", "Furosemide", etc.
- Nitrates such as Nitroglycerin.
- Calcium channel blockers - Nifedipine and others.
- Myotropic antispasmodics - "Eufillin."
To reduce the antihypertensive effect of Andipal, its combination with the following drugs is capable of:
- Analeptics - Camphor, Citizin, Sulfocamphocaine, etc.
- Tonic preparations, for example, tincture of ginseng, Rhodiola rosea, Eleutherococcus, etc.
- Adrenomimetics - Adrenaline, Ephedrine, etc.
The instructions also say that the combination of “Andipal” with drugs from the group of opioid analgesics can cause the development of undesirable reactions. With simultaneous administration with enterosorbents, the drug is worse absorbed in the gastrointestinal tract. The same applies to antacids and those containing bismuth.
Analogs
The modern pharmaceutical market is ready to offer a number of similar drugs that have the same properties as Andipal. In particular, they include:
- "Papazol".
- "Analdim."
- Captopril.
- "Cofalgin."
- "Celebrex."
- Quatrox.
However, before switching to another drug, you should consult a doctor, since all of the above analogues have a number of contraindications.
Reviews of doctors about Andipal
As for the reviews, on the part of the doctors they are in most cases positive. However, it should be borne in mind that Andipal is an emergency aid and is most often prescribed to relieve an attack of hypertension. All experts emphasize that for regular intake with hypertension, it is better to choose other drugs that are more suitable for these purposes.
Reviews about Andipal from patients
As for the patient reviews, they are found both positive and negative. For some, the drug is not suitable individually. Or it has an effect at the beginning of administration, but over time the body gets used to it, and Andipal ceases to act. For other patients, only this drug is suitable. In addition, he, unlike many others, is cheap and affordable, you can buy it at any pharmacy. In this case, one should not forget about contraindications and possible side effects, therefore, the drug should be taken only as directed by the attending physician.
We reviewed the instructions for Andipal and the reviews.