The drug "Finasteride" helps to inhibit the enzyme that converts testosterone to dehydrotestosterone, reduce its concentration in the blood, as well as in prostate tissue. As a result, the stimulating effect on the development of adenoma in the prostate gland is reduced. The medicine helps to reduce the size of the enlarged prostate, increases the flow of urine. Due to the effect of the medication, the symptoms of benign type prostate hypertrophy are alleviated. To reduce the manifestations of pathology, it may take several months to take the drug. The medicine has good absorption, the drug penetrates into the fluid and tissues, its presence is detected in the ejaculate. The bioavailability of the drug is independent of food intake and is about 80%. The drug is excreted through the intestines and kidneys.
Means "Finasteride". Instruction Indications
The medication is prescribed for benign prostatic hyperplasia. The medicine is effective for reducing the size of the enlarged gland, reducing the symptoms of hyperplasia, increasing urine flow. The drug is prescribed to reduce the development of acute urinary retention, requiring surgery (prostatectomy or transurethral resection) or catheterization.
The drug "Finasteride." Instructions for use
Five milligrams is recommended per day. The drug is taken once a day. Therapy is prescribed for a long period.
Means "Finasteride". Instruction Adverse reactions
Negative manifestations are relatively rare due to treatment. The drug can provoke gynecomastia, angioedema, decreased libido, skin rash. In some cases, impotence, a decrease in the amount of ejaculate is noted.
Medication Finasteride. Instruction Contraindications
The drug is not prescribed for children and women. The drug is contraindicated in men who have hypersensitivity to the components, prostate cancer, obstructive uropathy. Before starting therapy and during it, a rectal examination and other diagnoses by other methods for the presence of prostate cancer are mandatory. Women during pregnancy and reproductive age are recommended to avoid contact with the medication, due to the fact that the drug has a teratogenic effect.
additional information
Caution when prescribing the drug "Finasteride" (reviews of experts confirm this) should be observed with patients with renal failure. Against the background of a large volume of residual urine or its sharply reduced current, the likelihood of obstructive uropathy should be considered. In practice, there was no significant interaction of Finasteride with the medicines Wafarin, Theophylline, Gliburide, Digoxin, Propanolol, Antipyrine. There is no significant effect of the drug on the cytochrome P450 system. In this regard, there is no effect of the drug on the pharmacokinetic parameters of drugs undergoing metabolism in the liver cells. Before using the Finasteride medication, a specialist should warn the patient about the need for long-term treatment.