The preparation “Neurodiclovit” calls the instructions for use an effective non-steroidal agent that has anti-inflammatory, anti-aggregate, analgesic and antipyretic effects. The above medicine perfectly eliminates the symptoms of neuralgia, degenerative diseases of the joints and relieves pain, which occurs with all kinds of inflammations of a non-rheumatic nature. Read on for more details about the drug "Neurodiclovit." Its price is also listed below.
Neurodiclovit tablets: a brief description
The above preparation is available in the form of gelatin capsules, which have a brown cap and a pinkish-yellow body. Inside these pills contains diclofenac sodium in the form of white granules and vitamins in the form of pink powder.
The drug for use advises you to store away from children, in a well-darkened and dry place. The temperature of the room where the remedy is located should not exceed 25 degrees Celsius.
Subject to all storage standards, the shelf life of the drug is 2 years.
It should also be noted that this tool affects the ability to control mechanisms and to drive vehicles. Therefore, while taking the above drug, you need to refrain from such activities.
This medicine is dispensed in a pharmacy according to a special prescription.
The composition of the drug "Neurodiclovit"
The medicinal product contains the following substances:
- diclofenac sodium;
- cyanocobalamin;
- thiamine hydrochloride;
- pyridoxine hydrochloride;
- other substances.
Also, the drug "Neurodiclovit" (instructions for use confirms this), includes such excipients:
- talc;
- ethyl acrylate copolymer;
- triethyl acetate;
- methacrylic acid;
- povidone K25.
One package contains 10 capsules.
The drug "Neurodiclovit" the instruction calls an oral therapeutic agent. Sodium diclofenac is perfectly absorbed for two hours. B vitamins are absorbed in the intestines.
About 60% of diclofenac sodium is excreted by the urinary system, 30% - by the intestines. The instruction indicates that the patient's age does not affect the pharmacokinetics of sodium diclofenac at all. It should be noted that this substance passes into breast milk.
pharmachologic effect
The drug "Neurodiclovit" describes the instructions for use as a therapeutic agent in which vitamins of group B and sodium diclofenac are combined. The latter is a non-steroidal anti-inflammatory substance. Together with neurotropic sodium vitamins, diclofenac quite effectively relieves pain and significantly reduces the level of inflammation in pathologies of the musculoskeletal system and neuralgia.
The accompanying drug "Neurodiclovit" instructions for use contain information that this is a narcotic analgesic. The main substance that is part of it is sodium diclofenac. It inhibits lipoxygenase and cyclooxygenase, contributes to the process of reducing the synthesis of inflammatory mediators, mainly prostaglandins. Diclofenac is characterized by the ability to reduce the intensity of the development of inflammation, relieve swelling, as well as joint pain.
B vitamins act as coenzymes and produce a neurotropic effect on the patient's body. Thiamine plays a significant role in fat, protein and carbohydrate metabolism. In addition, the aforementioned substance promotes nervous excitement in synapses.
In order for the peripheral and central nervous systems to function normally, the patient needs vitamin B6. This substance is an active participant in the biosynthesis of many neurotransmitters, such as serotonin, adrenaline, dopamine, norepinephrine, histamine, etc.
Cyanocobalamin has a significant effect on the normal implementation of blood formation processes. The above vitamin promotes the maturation of red blood cells. This substance is one of the active participants in biochemical reactions. This is the synthesis of nucleic acids, the exchange of amino acids, lipids and carbohydrates, the transfer of methyl groups. Coenzymes of cyanocobalamin are adenosylcobalamin and methylcobalamin. They promote cell replication and growth.
Instructions for use certifies that B vitamins potentiate the analgesic effect of diclofenac sodium.
Neyrodiklovit tablets: indications for use, price
The drug is popular among many experts. So, what are Neurodiclovit tablets from? This preparation instruction suggests using for the treatment of the following diseases:
- acute gouty arthritis;
- defeat (rheumatic) of soft tissues;
- neuralgia (lumbago, cervical syndrome, sciatica);
- degenerative and inflammatory diseases of the spine and joints (rheumatoid arthritis, osteoarthritis, rheumatoid arthritis, spondylarthrosis, chronic polyarthritis, ankylosing spondylitis);
- pain when observing signs of inflammation that are non-rheumatic in nature (after dental and surgical interventions, in inflammatory processes in the ENT region (tonsillitis, pharyngitis, otitis media), in gynecological diseases (adnexitis, primary algodismenorrhea), and also after injuries) .
The price of the drug is on average 220 rubles of the Russian Federation for 30 capsules.
Contraindications
The drug "Neurodiclovit", the indications for use of which are described above, are not allowed to be taken by all patients. It depends on the individual characteristics of the patient's body. So, there is a group of patients who are absolutely contraindicated to use the drug "Neurodiclovit" in a therapeutic course. The instruction indicates a number of diseases in which it is undesirable to use this therapeutic agent:
- intracranial hemorrhage;
- erosive and ulcerative formations in the digestive organs;
- bronchial asthma, which is also accompanied by symptoms of polyposis of the nasal mucosa;
- violation of hemostasis;
- violation of blood formation.
With caution, the drug "Neurodiclovit" is recommended by the instruction for signs of the following diseases:
- bronchial asthma;
- anemia;
- arterial hypertension;
- heart failure (congestive);
- edematous syndrome ;
- alcoholism;
- liver failure;
- diabetes mellitus;
- renal failure;
- induced porphyria;
- diverticulitis;
- inflammatory diseases of the digestive tract;
- systemic diseases of the connective tissue.
In addition, the instruction prohibits the use of Neurodiclovit tablets for small patients, that is, children. The above remedy is also contraindicated for mothers who are breastfeeding, and women in position. Experts note that this drug can contribute to the development of malformations in the embryo or fetus. Also, with mother's milk, sodium diclofenac passes to the baby, which can adversely affect its health.
Also, elderly people are advised to use caution with the drug "Neurodiclovit" instructions for use. Tablets, in addition, should not be given to patients if they are undergoing rehabilitation after extensive surgical interventions.
Side effects
In some cases, side effects may occur when using the drug "Neurodiclovit." Indications for use and recommended dosages sometimes do not bring the desired result. On the contrary, some patients after taking the above drug complain of unpleasant sensations and conditions:
- from the nervous system: dizziness, drowsiness, sleep disturbance, headaches, irritability, depression, general weakness, cramps, disorientation, a sense of fear, aseptic meningitis, nightmares;
- from the digestive tract: diarrhea or constipation, abdominal pain, nausea, peptic ulcer with various symptoms of complications, flatulence, dry mucous membranes, sensation of bloating, aphthous stomatitis, gastrointestinal bleeding, liver necrosis, vomiting, hepatorenal syndrome, liver cirrhosis, change in appetite, cholecystopancreatitis, colitis, pancreatitis;
- from the sensory organs: blurred vision, scotoma, taste disturbance, diplopia, tinnitus;
- from the genitourinary system: fluid retention, oliguria, proteinuria, hematuria, nephrotic syndrome, papillary necrosis, renal failure (acute), azotemia;
- from the respiratory system: cough, pneumonitis, bronchospasm, laryngeal edema;
- on the part of the heart: increased arterial pressure, chest pain, heart failure (congestive), myocardial infarction.
In addition, you may experience:
- anaphylactic shock, swelling of the tongue and lips, anaphylactoid reactions, allergic vasculitis;
- skin rash or itching, erythema multiforme, exudative urticaria, toxic dermatitis, eczema, increased photosensitivity, epidermal toxic necrolysis, small hemorrhages, alopecia.
It is very important to consider indications for use and not only when using the drug "Neurodiklovit". In no case can one fail to pay attention to the above side effects. If these symptoms are observed, the patient recommends that the patient stop using the Neurodiclovit drug. The reviews of specialists contain tips that such a patient must seek qualified medical help.
How to take the above drug? Overdose
Capsules should be washed down with a sufficient amount of liquid. The drug should be taken during meals.
For adult patients, specialists usually prescribe 1 capsule every 8 hours at the initial stage of treatment. The patient will consume approximately 100 mg of diclofenac sodium. Then the dosage changes a little: the drug should be taken 1-2 times a day as maintenance therapy.
For patients under 14 years of age, the maximum dosage of the above medication should not exceed 2 capsules per day.
Older people are better off not using this drug for medicinal purposes or treat it with great care.
The duration of the course of therapy depends on the severity and nature of the disease.
Experts warn that it is very important to comply with this norm and in no case do not exceed it without a doctor’s permission. Otherwise, symptoms of an overdose of the drug may occur. This headache, cramps, nausea, impaired kidney and liver, shortness of breath, abdominal pain, blurred consciousness. In this case, experts advise to immediately carry out the following actions:
- thoroughly rinse the stomach;
- take activated charcoal tablets;
- seek medical help (forced diuresis and symptomatic therapy are carried out).
The interaction of this drug with other therapeutic agents
Using the above drug, it should be remembered that it increases the plasma concentration of methotrexate, digoxin, cyclosporin and lithium. In addition, the Neurodiclovit remedy is distinguished by the following interaction with other drugs:
- minimizes the effect of hypoglycemic drugs;
- reduces the effects of sleeping pills and antihypertensive drugs;
- enhances the effect of therapeutic agents that cause photosensitivity;
- helps to increase the likelihood of side effects of other GCS and NSAIDs;
- increases cyclosporine nephrotoxicity and methotrexate toxicity;
- lowers anti-Parkinsonian high efficiency levadopa.
You should also take into account other nuances in the interaction of the drug "Neurodiclovit" with other therapeutic agents:
- acetylsalicylic acid significantly reduces the concentration of diclofenac in the blood;
- ethanol prevents the absorption of thiamine into the blood;
- drugs that block tubular secretion increase the toxicity of diclofenac;
- biguanides and colchicine minimize the absorption of cyanocobalamin.
If the drug "Neurodiclovit" is simultaneously used in combination with therapeutic agents from St. John's wort, bleeding in the digestive tract may occur.
It should also be remembered that the substance paracetamol significantly increases the risk of nephrotoxic effects of diclofenac sodium.
Preparations that contain in their composition valproic acid, cefotetan, plikamycin, cefamandol, in combination with the above therapeutic agent can contribute to the development of hypoprothrombinemia.
The drug "Neurodiclovit": analogues
The price of the above funds is acceptable, according to patient reviews. But sometimes there are situations when you just need to know how you can replace the above tool. For example, the drug “Neurodiclovit” may simply end in a pharmacy. Its analogs are as follows:
- "Block B12";
- Tsinepar
- Bol Run
- Diclofenac
- Flamidez
- Dolex
- Olfen 75;
- Fanigan
- Diclocaine;
- "Diclofenac With Paracetamol";
- "Maksigezik".
It should be noted that the group of drugs for pain in the back, muscles and joints also includes the drug "Neurodiclovit." Its analogues here are Mirlox, Ben-Gay, Melbek.
In addition, the above medicine also applies to such a group of anti-inflammatory non-steroidal agents. Substitutes for the Neurodiclovit preparation here are such products as Analgin-Ultra, Bi-Xikam, Ksefokam.
The group of drugs for the treatment of diseases of the joints and spine also includes the drug "Neurodiclovit."
Analogues, the price of which is sometimes much higher, are far from being used in all cases instead of Neurodiclovit. It should be noted that the use of a substitute for the drug is possible only after consultation with an experienced specialist. Doing this yourself is by no means recommended.
The opinion of doctors about the drug
The responses of specialists are mostly positive if we consider the assessment of the therapeutic effect of the drug "Neurodiclovit." Doctors' reviews contain information that its effectiveness is already noticeable after the first course of therapy. It is important only to strictly observe the dosage prescribed by the doctor. In addition, doctors claim that side effects are extremely rare.
Reviews of experts emphasize that during the course of therapy with the above drug it is very important to systematically monitor the status of peripheral blood, kidneys and liver function, as well as conduct fecal studies for the presence of blood in it.
Patient feedback
Many patients note the high therapeutic effectiveness of the drug "Neurodiclovit." Reviews of patients suffering from intercostal neuralgia suggest that this drug easily relieves the symptoms of exacerbation of the disease. It becomes much easier to move, the tool acts very quickly.
In addition, many patients claim that the Neurodiclovit drug, the price of which, in their opinion, really justifies itself, also relieves pain in the head, spine, hypochondrium (with biliary colic) and even in the teeth.
Some patients indicate that the long-term course of therapy is a major drawback of the above medication. In some cases, after such treatment, patients begin to have problems with the stomach.
The drug "Neurodiclovit", the price of which is quite acceptable for most patients, is indeed a fairly effective drug. It must be taken according to the doctor’s prescription, in no case exceeding the dosage. If any side effects occur, you should immediately seek medical help.