"Sonisin" is used to eliminate disorders of the bladder emptying process, which are associated with benign prostatic hyperplasia. The medication is in the form of modified release capsules. The composition of the drug includes the following substances:
- tamsulosin hydrochloride;
- calcium stearate;
- ethyl citric acid;
- talc;
- ethyl acrylate copolymer;
- methacrylic acid;
- cellulose.
The article will consider reviews, instructions for use and analogues of "Sonizin".
Pharmacological actions
The drug belongs to alpha-blockers. Due to the action of the drug, a decrease in the tone of the smooth muscles of the prostate is observed. This leads to a reduction in the signs of irritation associated with benign prostatic hyperplasia.
The therapeutic effect, as a rule, occurs two weeks after the start of the use of Sonizin, although in some patients a decrease in the severity of symptoms is noted already on the first day of use of the medication.
Indications and contraindications
According to the instructions for use, "Sonizin" is recommended to eliminate dysuria, which is associated with benign prostatic hyperplasia. The drug is contraindicated in people with individual intolerance to the substances of the drug. Additional restrictions are:
- Arterial hypotension (decrease in blood pressure by more than 20 percent).
- Severe illness.
- Kidney disease.
Instructions for use
"Sonisin" must be used orally, preferably at the same time, after a meal, washed down with water. In order not to disrupt the release of the active component, the capsule cannot be chewed. The recommended dosage is 1 capsule per day. The cost of the drug varies from 400 to 550 rubles.
Side effects
Like any other medication, "Sonisin" is able to provoke undesirable reactions:
- Nausea.
- Constipation.
- Diarrhea.
- Vomiting.
- Asthenia (a painful condition that is manifested by increased fatigue).
- Dizziness.
- Migraine (a neurological disease, the most frequent and characteristic sign of which is episodic or regular severe pain).
- Sleep disturbances.
- Heartbeat
- Tachycardia (a sharp increase in heart rate, is a sign of serious disorders).
- Orthostatic hypotension (a clinical syndrome characterized by impaired ability of the body to maintain a normal level of blood pressure in an upright position).
- Decreased libido (energy of psychic, including sexual drives).
- Retrograde ejaculation (violation of ejaculation, which is characterized by improper passage of seminal fluid).
- Angioneurotic edema (acute condition, which is characterized by the rapid appearance of edema of the mucous cavity, as well as subcutaneous tissue and the skin itself).
- Skin rashes.
- Itching
- Rhinitis (runny nose).
- Pain in the back.
To restore blood pressure and stabilize the heart rate, the patient should be laid down. In this case, cardiotropic therapy is recommended. It is necessary to monitor the functioning of the kidneys and carry out general supportive treatment.
While maintaining unpleasant signs, the use of volume-replacing and vasoconstrictive drugs will be required. To prevent further absorption of the active substance, gastric lavage can be prescribed, as well as the use of enterosorbents, activated carbon.
Analogs "Sonizina"
Substitute List:
- Hyper simple.
- Glansin.
- Tamsulon.
- Tamzelin.
- Omnic.
- Focusin.
- Tamsulosin.
- Tulosin.
- "Proflosin".
Before replacing "Sonizin" with an analogue, you should consult a doctor to exclude contraindications.
Omnic
The active ingredient is tamsulosin hydrochloride. Additional substances are:
- cellulose;
- polysorbate 80;
- triacetin;
- titanium dioxide;
- indigotine;
- iron oxide yellow;
- gelatin;
- talc;
- calcium stearate;
- sodium salt of lauryl sulfuric acid.
Before you start using drugs, you need to clarify the diagnosis and exclude the presence of other pathologies in the body. With caution, the drug Omnic is used if there is orthostatic hypotension in the medical history.
From the instructions for use with the Sonizin analogue, it is known that alpha-blocker does not adversely affect the ability to drive a car or carry out work that requires increased attention and speed of psychomotor reactions. The price of Omnik ranges from 350 to 2800 rubles.
Hyperprost
The drug is forbidden to use with increased sensitivity to any of its components. Caution during therapy should be observed in the following situations:
- chronic kidney damage;
- severe liver disease;
- low pressure.
According to the instructions for the analogue of "Sonizin", the composition of the medication includes:
- tamsulosin hydrochloride;
- ethyl cellulose;
- sucrose;
- mannitol;
- povidone;
- indigo carmine;
- gelatin;
- water;
- titanium dioxide.
According to the reviews of patients and doctors, the medication can only be used after a full examination. When the first symptoms of orthostatic hypotension occur - weakness, as well as dizziness - a person must be laid down or seated. During therapy, caution should be exercised when carrying out work with potentially dangerous consequences.
Glansin
After oral use, the active substance is well absorbed in the intestine. The drug has almost 100% bioavailability. If you take "Glansin" during meals, the absorption process is somewhat slowed down. Therefore, it is recommended to use the drug before meals.
The composition of the medicine:
- tamsulosin hydrochloride pellets;
- sugar grains;
- macrogol;
- isobutenic acid;
- ethyl acrylic acid;
- ethyl cellulose.
Before using the drug, an examination should be performed to exclude other diseases that may manifest with the same symptoms. Prior to initiating therapy and periodically during treatment, a regular examination should be performed.
Particular caution when taking the drug should be observed for persons with symptoms of its development, the patient should sit down or lie down and remain in this position until the unpleasant signs disappear completely.
Due to the likelihood of narrow pupil syndrome, if surgery is necessary for glaucoma and cataracts, you need to stop taking the medication in one to two weeks.
In addition, it is important to inform the surgeon about the use of the medicine so that he takes this into account when preparing and conducting the operation. The cost of the drug varies from 370 to 1,200 rubles.
Proflosin
Alpha-1 blocker, which is used for urination problems that are provoked by benign prostatic hyperplasia. This is an analogue of "Sonizin" (photo of the drug is presented above).
Structure:
- focusin;
- ethyl acrylic acid;
- isobutenic acid;
- cellulose;
- talc;
- triethyl citrate.
After taking the medication, the absorption of tamsulosin from the stomach and intestines is carried out almost completely and quickly. The rate of absorption decreases while taking food. The maximum blood level after using a single dosage of the drug is reached after about 6 hours.
If dizziness or weakness occurs, which may be the first signs of orthostatic hypotension, the patient should sit down or lie down.
The appearance of Quincke's edema in humans with the use of the analogue of the drug "Sonisin" indicates increased sensitivity to the active substance. Therefore, therapy must be stopped immediately; repeated use of Proflosin is prohibited in this situation.
With cataract surgery, there is a possibility of the appearance of atonic iris syndrome in patients who use this medication. Therefore, it is important to warn the doctor about the use of Proflosin so that he takes this fact into account. The cost of the drug varies from 400 to 1,300 rubles.
Tamsulosin
A medication that is designed to eliminate urination disorders with benign prostatic hypertrophy. This is a cheap analogue of "Sonizin", its cost varies from 400 to 900 rubles.
The composition of the medicine includes:
- tamsulosin;
- 2-methylpropenoic acid;
- ethyl acrylic acid;
- triethyl citrate;
- talc;
- water.
Before using Tamsulosin, it is important to ensure that there are no other diseases that can trigger the same unpleasant symptoms. Before the start of therapy, certain examinations are also performed.
Tulosin
An alpha-blocker that competitively blocks postsynaptic adrenergic receptors located in the smooth muscles of the bladder neck and prostate. From the instructions and reviews for the analogue of "Sonizin" it is known that the following components are included in the structure of the medication:
- tamsulosin;
- cellulose;
- a salt of calcium and stearic acid;
- ethyl acrylic acid;
- 2-methyl-2-propenoic acid.
With the help of the action of the active component, the tone of the smooth muscles of the prostate gland, as well as the neck of the bladder, is reduced, the functioning of the detrusor is improved. As a consequence of these effects, the drug provides relief from signs of irritation and obstruction.
According to reviews, the pharmacological effect of the drug is noted, as a rule, two weeks after the start of therapy, but in some people, a decrease in the severity of symptoms can be observed already after taking the first dose. The cost of Tulozin varies from 500 to 600 rubles. What other drugs are included in the review of Sonizin analogues?
Focusin
A drug that is aimed at eliminating urination disorders that are caused by benign prostatic hyperplasia.
The structure of the drug:
- tamsulosin hydrochloride;
- gelatin;
- cellulose;
- silica;
- dibutyl sebacate;
- talc.
The therapeutic effect of the drug is based on its ability to block postsynaptic alpha-adrenergic receptors located in the neck of the bladder, smooth muscles of the prostate gland.
In addition, the drug has the ability to block adrenergic receptors like Alpha1D, which are usually found in the body of the bladder. Subsequently, there is a decrease in the tone of the smooth muscles of the above organs, and the functioning of the muscles of the urethra is also improved. This, in turn, entails a decrease in signs of irritation and obstruction caused by prostatic hyperplasia.
According to the annotation, to Fokusin, the pharmacological effects of the use of a medication occur within two weeks from the start of use. In rare situations, there is a decrease in the severity of symptoms after the first dosage. The price of a medicine ranges from 400 to 1,400 rubles.
Zoxon
An antihypertensive drug is also effective for benign prostatic hyperplasia as a drug that reduces urination disorders.
"Zoxon" is another name for the analogue of "Sonisin". In the composition of:
- doxazosin mesylate;
- granulated cellulose;
- lactose;
- silicon dioxide colloid;
- sodium carboxymethyl starch;
- magnesium salt of stearic acid;
- sodium salt of lauryl sulfuric acid.
When applying Zoxon to patients with benign prostatic hyperplasia, urodynamics improve and symptoms of the disease decrease. The positive effect of the medication is due to blockade of alpha1-adrenergic receptors, which are located in the stroma of the prostate and in the neck of the bladder.
Subsequently, lowering the total peripheral vascular resistance significantly decreases blood pressure. Clinically significant antihypertensive effect is achieved with the appointment of "Zoxon" once a day and lasts for an hour.
In this case, blood pressure decreases gradually, and the maximum is observed 2-6 hours after taking the tablets. The drug has a beneficial effect on the lipid profile of the blood, greatly reducing the level of cholesterol and triglycerides, thereby helping to reduce the likelihood of cardiac ischemia.
"Zoxon" reduces hypertrophy of the left ventricle of the heart, inhibits the production of platelets and reduces the tendency to thrombosis. The medication can be used in patients with diabetes mellitus, as well as people with gout, bronchial asthma, since it does not have a negative effect on metabolism.
The bioavailability of the drug is seventy percent. With impaired liver function and the use of drugs that alter hepatic metabolism. Its excretion from the blood is considered two-phase, the final half-life is 22 hours.
Conclusion
In most situations, drug reviews confirm that the patient's condition improves after treatment. According to men who have been diagnosed with prostate damage, they are undergoing a full course of therapy with the prescription of these drugs.
Such pharmacological treatment is effective, but only for a certain time. After discontinuation of therapy, all negative symptoms return again. To start using such alpha-blockers should only be prescribed by a medical specialist.