A person is surrounded by a huge number of different microorganisms, which under certain circumstances (decreased immunity, the period of the epidemic) can cause infectious diseases. In the absence of timely assistance and effective drug therapy, complications may develop. In order to prevent this from happening, you need to use reliable means. For example, lincomycin hydrochloride is a well-known antibacterial drug.
Release form
This medicine for many years is available in several forms:
- Ampoules with an injection solution of 1 ml, in each of which 300 mg of pure drug.
- Capsules of 250 and 500 mg.
- Ointment for external use.
Therapeutic effect
The main effect is bacteriostatic. This means that the drug disrupts protein synthesis, which is necessary for pathogenic microorganisms for normal functioning.
The range of action of lincomycin hydrochloride is quite wide. It is able to destroy bacteria such as:
- Staphylococcus aureus.
- Actinomyces israelii.
- Streptococcus viridans.
- Streptococcus agalactiae.
- Bacteroides spp. (Excluding B.fragilis).
- Chlamydia trachomatis.
- Mycoplasma hominis.
Indications for use
Due to the directed action on many bacteria, lincomycin hydrochloride has a wide list of indications. This includes any infections that are caused by bacteria that are sensitive to lincomycin. Namely:
- pneumonia;
- lung abscess;
- osteomyelitis;
- sepsis and so on.
Contraindications
Lincomycin hydrochloride has a systemic effect on the human body, therefore there are a number of conditions in which its use is dangerous and therefore strictly prohibited. Contraindications include:
- High sensitivity to lincomycin or other antibiotics of the lincosamide group (for example, clindamycin). Otherwise, a severe allergic reaction in the form of a rash, itching or Quincke's edema may develop.
- Due to the fact that the drug strongly affects the functioning of the liver and kidneys, it is forbidden to use it in case of impaired function of these organs.
- The drug passes into breast milk, therefore, the drug is prohibited for women who breast-feed a baby.
- In addition, the instructions of lincomycin hydrochloride indicate that it has a teratogenic effect. Therefore, its use by pregnant women is unacceptable.
Side effects
Like any other drug, lincomycin hydrochloride can have a negative effect on various body systems.
For example, digestive system malfunctions are possible. This is usually manifested by nausea, vomiting, upset stools, abdominal pain.
According to the information specified in the instructions for use, lincomycin hydrochloride changes the composition of the blood. It becomes few leukocytes, platelets, neutrophils.
In addition, the development of candidiasis, stomatitis, glossitis is possible.
The occurrence of allergies is not excluded.
With a quick injection, a decrease in pressure, muscle weakness, and dizziness are possible.
Dosage and administration
Lincomycin hydrochloride capsules are prescribed as follows:
- adult - 500 mg 3-4 times a day;
- adolescents from 14 to 18 years old - 250 ml each;
- for children from 1 month to 14 years, the dosage is calculated individually and depends on body weight according to the formula 45 mg / kg per day.
When using injection forms:
- The drug is pre-dissolved in 250 ml of 0.9% sodium chloride solution or 5% glucose and is administered intravenously at 600 mg 1-2 times a day. When administered intramuscularly, these numbers are similar.
- For children, the drug is administered intravenously. The dosage is calculated according to the formula - 10-20 mg / kg every 12 hours.
When using the external dosage form, lincomycin is applied to the affected area several times a day.
Terms and conditions of storage
Lincomycin hydrochloride, regardless of the chosen form of release, is stored the same.
The main conditions:
- Humidity is not higher than 65%.
- Air temperature is not higher than 30 degrees.
- Lack of sunlight.
- Away from small children.
The shelf life of the injection form is 2 years from the date of production.
In capsules for oral administration - 3 years.
Ointment for external use - 3 years.
Pharmacy Vacation Terms
Like any other antibiotic, lincomycin hydrochloride is a prescription drug, therefore, to purchase it, you must first consult a doctor. And he, if he considers it necessary, will write a prescription on the form of a strictly defined sample indicating all the main and additional details.
With this recipe, you should contact the pharmacy organization, where the pharmacist (or pharmacist) will verify the correctness of the document and release lincomycin hydrochloride.
Drug cost
The exact price depends on the chosen form of release, as well as the dosage of the drug.
For instance:
10 pieces of lincomycin hydrochloride in ampoules will cost the buyer about 100-150 rubles.
Capsules 250 mg of 20 pieces - 50-100 rubles, and 500 mg of 20 pieces - 80-130.
A tube of ointment with a volume of 15 grams with a concentration of 2% will cost about 70-120 rubles.
Regardless of the form of release of lincomycin, hydrochloride is a very low-cost drug.
Conclusion
The use of lincomycin hydrochloride has been tested for years, because the drug has been on the pharmaceutical market for decades. During this time he proved himself to be excellent.
Another advantage of the drug is its low cost. Indeed, with respect to other antibiotics on the pharmaceutical market, the cost of which sometimes reaches 1000 rubles per pack, the price of lincomycin is quite reasonable.
Nevertheless, it should be borne in mind that some types of bacteria may have resistance to lincomycin hydrochloride. Therefore, with certain infections, the drug may be ineffective.