In the article, we consider the instructions for use with Furazolidone.
It is an antibacterial agent used mainly in the field of urology. The drug allows you to effectively deal with the causative agent of the disease, causing adverse reactions is extremely rare. In the treatment of children, a suspended form of the drug can be used, which also has a detrimental effect on pathogens in the digestive tract.
So, let's figure out what “Furazolidone” treats and helps?
Pharmacological forms
The manufacturer produces the drug in tablet form. Each cardboard package contains 2 blisters, each of which contains 10 tablets. For the treatment of pediatric patients, a preparation is produced in the form of granules, which are used to make the suspension.
Composition, description
According to the instructions for use, "Furazolidone" is included in the group of antibacterial drugs of a number of nitrofurans. The drug is effectively used in the treatment of many diseases of infectious etymology. It is able to have an antimicrobial effect, highly effective, low toxicity, well tolerated by patients. Most often, "Furazolidone" is used in the treatment of dermatological, gastroenterological, urological and nephrological diseases. Compared with other antibacterial drugs, this drug has a reasonable price. “Furazolidone” does not have structural analogues, therefore, if replacement is necessary, only drugs with a similar mechanism of action can be used.
Each tablet "Furazolidone" contains as an active component furazolidone in an amount of 0.05 g, as well as a number of auxiliary components.
Pharmacological group
As indicated by the instructions for use with Furazolidone tablets, the medication is an antimicrobial agent belonging to the group of nitrofurans. Against the background of the use of the drug, aggressiveness and the ability to reproduce an extensive number of bacteria with pathogenicity are suppressed. Among microorganisms sensitive to furazolidone are gram-negative and gram-positive bacteria, salmonella, trichomonads. These pathogens most often provoke diseases affecting the genitourinary system. The high activity of the drug does not apply to purulent and anaerobic infections.
The mechanism of the effect of the drug allows at the cellular level to disrupt the respiration of pathogens, suppress their reproduction, and inhibit the biological processes. As a result, the bacterial membrane is destroyed, their reproduction stops, and further penetration into the deeper layers of tissues. Under the influence of the drug, the level of toxins produced by bacteria decreases. Thus, the patient's condition improves, the risk of acute intoxication as a result of the influence of bacterial vital products is reduced.
"Furazolidone" is a preparation of synthetic origin. Its administration is accompanied by a pronounced bacteriostatic effect, persistent antimicrobial action. The medication is able to disrupt the integrity of the shells of bacterial cells, block their growth and subsequent reproduction, thereby reducing the likelihood of complications, and also accelerate recovery.
Indications for use
In accordance with the instructions for use, "Furazolidone" is indicated for use in some cases. The advisability of using this antibiotic in each case should be determined by the doctor.
For adult patients, the drug is prescribed as an element of the complex therapy of diseases such as:
- Food intoxication.
- Cystitis.
- Vaginitis.
- Giardiasis
- Enterocolitis.
- Diarrhea of infectious etymology.
- Typhoid
Indications "Furazolidone" in the instructions for use are described in detail. Granules intended for the manufacture of a suspension can be used in the treatment of the following diseases in children:
- Burns, infected wounds.
- Infections affecting the genitourinary system.
- Parasitic lesions.
- Intestinal infections.
It can be prescribed to children only by a pediatrician and only with strict indications. In this case, the dosage of the drug should be selected individually.
As we are informed by the instructions for use for Furazolidone tablets, during pregnancy, as well as breastfeeding, it is recommended that women refrain from using the product. But during clinical trials, there were no cases of negative effects of the active component on the fetus. In this regard, the medication may be admitted to the indicated category of patients, but only if the doctor considers it appropriate. Pregnant women "Furazolidone" is sometimes prescribed for the treatment of cystitis, giardiasis, intestinal infections and some other diseases.
It is important to follow the instructions for use with Furazolidone. The price of the drug is quite reasonable.
In clinical trials, cases have been identified where the use of "Furazolidone" during lactation provoked the development of a child's lack of glucose-6-phosphate dehydrogenase, hemolytic anemia and other adverse conditions. In this regard, the need to use the medication should be determined by the doctor, and it is recommended that the woman suspend breast-feeding for the period of therapy. This is confirmed by the instructions for use with Furazolidone.
Contraindications
This medication, like any drug, has a number of contraindications, such as:
- Children's age up to 1 year.
- The lactation period.
- Renal failure in chronic form.
- Pregnancy.
- Individual hypersensitivity to any component that is part of the drug.
Caution should be exercised when using the drug in patients who suffer from CCC and NS pathologies, glucose-6-phosphate dehydrogenase deficiency.
Let us consider in more detail the instructions for use for "Furazolidone" for adults and children.
Using
An antibacterial medication should be recommended to the patient only after the diagnosis is clearly identified. The treatment regimen and dosage should be selected individually. So it is said in the instructions for use for tablets "Furazolidone" for adults and children.
Adult patients are advised to adhere to a treatment regimen that is determined taking into account the causative agent of the disease. As a rule, take up to 2 tablets three times a day. The average duration of therapy may take 3-7 days. The drug shows its effectiveness already on the second day of use.
In childhood, the suspension form of "Furazolidone" is prescribed. Children 1-3 years old are shown a single dose of up to 5 ml of suspension per day. Children 3-5 years are shown a single use of up to 7 ml per day. Children from 5 years old should take up to 28 ml of suspension once a day. Each bottle with granules is equipped with a measuring spoon, which allows you to correctly measure the required dose of the drug, and, thus, eliminate the likelihood of an overdose.
Pregnant women "Furazolidone" is prescribed extremely rarely, only in exceptional cases, therefore, the dosage of the drug should be determined individually for each patient.
Negative impact
According to the instructions for use with "Furazolidone" for adults and children, the drug has low toxicity, is well tolerated by patients, however, the likelihood of negative reactions still exists. With the use of Furazolidone, the following may develop:
- Epigastric pain.
- Allergic manifestations on the skin.
- Calls for vomiting, nausea.
- Decreased appetite.
If any of these negative symptoms develops, you should consult your doctor, as this may be a reason for changing the treatment regimen or completely discontinuing the drug. Furazolidone, if necessary, can be replaced by one of its closest analogues, among which are Enterofuril, Enterol, and Nifuroxazide.
Interaction with other medicines
Due to the fact that Furazolidone belongs to antibacterial medicines, it should not be combined with drugs of the same group. With the parallel use of tetracycline drugs, the effect of the drug increases. As a result, the likelihood of developing negative consequences increases.
This is indicated in the instructions for use with Furazolidone. Price and reviews are listed below.
Joint administration with antidepressants, monoamine oxidase inhibitors, ephedrine can provoke an increase in blood pressure.
It is strictly forbidden to combine the intake of the indicated antibiotic with alcohol.
If the patient suffers from any chronic pathologies, uses any medications, he must inform the doctor about it.
We will not consider in detail the instructions for use with analogues of Furazolidone.
Special instructions for use
It is strictly forbidden to start therapy with “Furazolidone” without the consent of a doctor. Only a specialist is able to determine the appropriateness of the use of this medication, to calculate the necessary dosage, application schedule.
If the diagnosis is not exactly known, additional studies should be done before you start taking Furazolidone.
Overdose
If the dosage regimen recommended by the doctor, the dosage of the drug are not respected, there is a risk of an overdose. The uncontrolled use of medications causes an increase in negative reactions in the form of:
- Acute intoxication.
- Polyneuritis.
- Acute toxic hepatitis.
Currently, the antidote to medicine is unknown, in this regard, if an overdose of furazolidone is suspected, the patient should contact the hospital, start taking salt laxatives and enterosorbents. That is, an overdose involves the appointment of symptomatic therapy.
This information is contained in the instructions for use with Furazolidone tablets for adults.
Analogs
"Furazolidone" has no structural analogues, there are only drugs with a similar therapeutic effect. Among them:
- Enterofuril. It is a therapeutic analogue of Furazolidone. It has a suspension and capsule form. It can be used by women during the lactation period. Its use in children from a year is allowed.
- "Macmirror." The active component in its composition is a derivative of nitrofuran - nifuratel. In the lactation period and during pregnancy should be used with caution.
- Stopdiar. Clinical and pharmacological analogue of “Furazolidone”. It is an intestinal antiseptic. The active substance in its composition is nifuroxazide. May have a tablet, suspension, capsule form. Its use in patients from 2 years is allowed. During pregnancy, during the lactation period should be used with caution.
- Phthalazole. It is an antibacterial medication that acts in the intestinal lumen. Its use in the treatment of children from 3 years is allowed.
If it becomes necessary to replace it with an analogue, it is important to consult a doctor.
In the instructions for use with "Furazolidone" price is not indicated.
Cost
In Russian pharmacies, the average cost of one package of funds is at the level of 80 rubles. However, it can fluctuate depending on the region of distribution and the pricing policy of the pharmacy chain, reaching the level of 200 rubles.
Reviews
There are mostly positive feedback on the experience of using "Furazolidone." Patients note the high effectiveness of the medication if it is used as an element of complex therapy for giardiasis, diarrhea, and Helicobacter pylori damage.
The drug is very well tolerated, negative effects on the background of its use develop very rarely. Another undoubted advantage is its affordable cost.
It is important to remember that the appointment of this medication should be carried out by a specialist.
We reviewed the instructions for use and reviews of "Furazolidone."