In the article, we consider the instructions for the Epigen spray.
The medication is a topical agent that is used both for therapeutic purposes and as a prophylaxis. The main indication for using the spray is considered to be the treatment of problems in the field of gynecology. The drug has antiviral and immunostimulating activity. It is made on the basis of a natural component obtained from a plant called licorice. Reviews about the Epigen spray are abundant.
Structure
The drug is available in the form of a spray, which is used externally and locally. The spray is packaged in special bottles, and the packaging is completed with a nozzle for use inside the vagina. The main active component of the drug is glycyrrhizic acid. In addition to it, Epigen spray includes such excipients as folic, fumaric, ascorbic, maleic acids, as well as propylene glycol and tween-80.
Glycyrrhizic acid is extracted from licorice root and is part of the drug, so it has an antipruritic, immunomodulating, anti-inflammatory, restoring and antiviral effect.
The properties
The drug has a detrimental effect on the DNA and RNA of various viruses, including cytomegalovirus, herpes, papillomas, etc. The antiviral effect occurs against the background of the indication of interferon. A medication has the ability to replicate viral cells at an early stage of their development. This occurs as a result of a selective dose-dependent slowdown of the P-phosphorylating type kinase.
Entering into interaction with virus structures, the active components of the drug change their cyclic phases, which leads to an irreversible process of inactivation of virus particles in a free state. "Epigen" prevents the invasion of virus proteins into healthy cells, disrupting their ability to produce new microorganisms.
In addition, Epigen has a mild anti-inflammatory and immunomodulatory effect. It reduces the activity and production of vosfolipase, as well as prostaglandins in activated macrophages and contributes to a more rapid movement of leukocytes to the affected area. The drug also helps supply cells with oxygen.
According to the instructions, the Epigen spray protects the cell membrane and also reduces the process of lipid oxidation, establishing a connection between free radicals and toxic elements. The healing effect of the drug promotes the regeneration of the skin and mucous membrane.
The use of Epigen spray is quite convenient, while the effect occurs only a few seconds after the irrigation procedure. The active component, subject to external use, tends to accumulate in affected areas. In this case, the absorption of active components into the systemic circulation is minimal and occurs very slowly, which eliminates the effect on the body and minimizes the likelihood of adverse reactions.
Indications spray "Epigen"
The drug is most often prescribed as a drug for the treatment of herpes virus infection in both acute and recurrent forms caused by the herpes simplex virus type 1 and 2. The shingles caused by the Varicella Zoster virus no less effectively eliminates the spray, but in this case it is used along with other medicines.
The medicine is often prescribed for the treatment of infection caused by the papillomavirus, as well as for prophylactic purposes in pathological processes in the uterine neck, as well as in genital warts. A spray is also used to prevent relapse of infectious diseases provoked by cytomegalovirus, herpes and papilloma.
"Epigen" is indicated as a therapeutic and prophylactic agent in conditions caused by a decrease in the local immune qualities. In case of vaginal dysbiosis, vulvovaginal candidiasis, bacterial vaginosis and a nonspecific colpitis, the drug is used as part of complex therapy in combination with other drugs. Also "Epigen" in the form of a spray is used to treat erosion. The medication effectively relieves pain and discomfort.
The spray has a regenerative effect on tissues, eliminates harmful microorganisms and prevents the occurrence of oncological processes. The drug eliminates discomfort in the genital area, accompanied by burning, itching, etc. At sexual contacts, the spray is used as a prophylactic to prevent viral and infectious diseases.
Instruction manual
Shake well before use. During irrigation, keep the bottle upright. To eliminate thrush, the drug is applied to the entire affected area, while the dispenser should be five centimeters from the skin.
Most often, the standard dosing schedule involves two clicks on the valve. For intravaginal use, it is recommended to use a special nozzle, which is included in the package of packaging with Epigen. It is a hollow pipe 7 cm long, at one end of which a valve is located, and at the other a spray.
For intravaginal use, the valve is removed from the vial, a nozzle is put in its place. Next, the nozzle is inserted into the vagina and injection is performed in an amount of 1-2 times. This method allows you to evenly spray the drug on the surface of the internal genital organs.
Within ten minutes after irrigation, you must remain in a supine position. After use, the nozzle should be washed in warm soapy water.
In men
Men can use the spray. In addition to external irrigation, injection of the drug into the urethra is allowed. With extragenital varieties of herpes infection, the irrigation procedure looks similar.
Epigen spray analogs will be considered below.
Multiplicity and duration of use
For the treatment of genital herpes and cytomegalovirus infection, the spray is used for two weeks five times a day. Spray is applied both externally and inside the vagina. If the infection recurs, Epigen is used for ten days, three irrigations per day. As a prophylactic and to prevent re-infection, the spray is used in the morning and evening, starting from the 20th day of the menstrual cycle.
When it comes to treating shingles, Epigen is applied up to six times a day. In this case, patients note a significant decrease in the number of rashes. The spray should be used until all signs of the rash have been resolved.
If the papillomas are located in the perianal region in close proximity to the genitals, irrigation of the affected areas of the body is prescribed up to six times a day. The drug is used for one week.
The spray is used to prevent the progression of infectious pathologies caused by the papilloma virus before and after intercourse. The drug is also prescribed when provoking factors appear, such as stress, overwork, taking antibiotics and cytostatics, disturbance of the vaginal microflora, viral infections of the respiratory type, etc. In this case, the drug is used three times a day.
Treatment of non-specific vaginosis and colpitis involves the use of a spray for a week.
Contraindications and adverse reactions
The drug is not recommended for use in identifying hypersensitivity to glycyrrhizic acid and other components that make up its composition. During the period of bearing a child, the use of the drug is allowed, however, only on the recommendation of a doctor and under control, subject to all necessary precautions. Spray "Epigen" during menstruation is undesirable.
The drug copes well with manifestations of candidal infection, and also prevents infection of the fetus during childbirth. The use of the spray is allowed during gestation and lactation only for critical indications and taking into account all possible consequences. Studies have not shown embryotoxic and teratogenic effects of the drug.
As for adverse reactions, the Epigen spray, according to patients and doctors, is well tolerated in the vast majority of cases. In exceptional situations due to individual intolerance, the development of an allergic reaction is possible.
Consider the recommendations for the treatment with Epigen spray.
Special recommendations
So that the drug affects the affected areas as efficiently as possible, rinsing them is not recommended. If adverse reactions such as skin irritation occur, you must abandon the use of Epigen.
In some cases, purulent formations may appear in the affected areas, as well as an unpleasant odor. In this case, consult a doctor as soon as possible.
Epigen does not actually have limitations when used with other drugs. Against the background of the simultaneous use of a spray with antiviral drugs, the effect of both drugs is enhanced. It is not recommended to combine the use of "Epigen" with interferonogens.
Epigen Spray Reviews
Reviews from patients are rather contradictory. There are comments that the drug did not have the expected effect. In other reviews, the drug is called highly effective and effective.
Quite a lot of patients got rid of thrush with a medication. Against the background of using the spray, itching and burning passed after several uses. This is confirmed by the reviews about the Epigen spray.
Many people use the drug as a means of prevention, especially during the period when immune deficiency occurs. The medication helped many to get rid of dryness and irritation that arose in the genital area. Some women, having started using the spray during pregnancy, continue to use it after childbirth.
Reviews of specialists
There are also reviews of doctors about the Epigen spray. It is considered an effective drug. Usually it is well tolerated, rarely causes side effects.
Gynecologists prescribe the drug during pregnancy, since it contains lactic acid and licorice, which contribute to the normalization of the vaginal microflora.
Similar drugs
Epigen spray has a lot of analogues. These include, for example, Glyciram, Epigen sex, Epigen labial. A doctor should select a replacement.