The drug "Azithromycin" refers to the antibiotics of the macrolide category. It is used to treat a variety of pathologies caused by pathogens sensitive to the main component of the drug. Instructions for use and analogues of "Azithromycin" will be considered in this article.
The composition of the medication
The product is available in the form of tablets, which are coated with an enteric coating and have a round shape, a shiny surface and white color. The main component of the drug is the antibacterial substance azithromycin, the content of which in one tablet is 500 mg. They are packed in contour cells of 3 pieces and a cardboard pack, which contains such a cell with tablets. Analogues of the drug "Azithromycin" should be selected by a doctor.
pharmachologic effect
The main active substance of the drug is an antibiotic of the macrolide group, which affects the ribosomes of pathological cells, as a result of which it disrupts protein synthesis with subsequent cessation of growth and death of the pathogen.
Depending on the concentration in which azithromycin is used, this substance can have an effective bacteriostatic effect, by inhibiting the growth and reproduction of bacteria, or bactericidal, leading to the death of these microorganisms,. In relation to infectious agents, this medication has a wide spectrum of activity, and has an overwhelming effect on the following infections:
- Gram-positive bacteria, which are streptococci and staphylococci.
- Gram-negative - bordetella, gardnerella, moraxella, legionella, Pseudomonas aeruginosa, Neisseria.
- Some varieties of anaerobic microorganisms are clostridia, bacteroids, peptostreptococci.
The drug "Azithromycin" has a fairly high activity against pathogens of many genital infections, for example, chlamydia, mycoplasmas, ureaplasmas, etc.
The tablets “Azithromycin”, getting inside the stomach, begin to dissolve quickly, and the active component is absorbed into the blood and evenly distributed over the peripheral tissues. It can be partially processed in the liver and subsequently excreted in the urine. Analogues of Azithromycin can be purchased at any pharmacy.
Indications for use
The main medical indication for taking the drug "Azithromycin" in tablets is a variety of infectious pathologies, the development of which is caused by microorganisms sensitive to the active component.
Its use is shown in the following cases:
- For diseases in the urogenital tract - urethritis (inflammation of the urethra), cervicitis (inflammation developing in the cervix), infections with sexual transmission - ureaplasmosis, chlamydia, mycoplasmosis, trichomoniasis, etc.
- ENT pathologies of an inflammatory nature - sinusitis (a disease developing in the paranasal sinuses), tonsillitis (an inflammatory process in the tonsils), otitis media (infectious disease of the middle ear).
- Infectious processes in the lower respiratory tract - bronchitis (an inflammatory process in the bronchi), laryngitis and tracheitis (inflammation of the vocal cords and trachea), as well as various forms of pneumonia (pneumonia).
- Infectious processes in the skin and soft tissues - in the initial stages of Lyme disease, as well as with erysipelas, pyodermatitis, impetigo.
- Peptic ulcer.
The drug can be used both independently and in combination with other antibacterial agents. This confirms the instructions for the Azithromycin. Analogs have the same indications.
Contraindications
When determining certain pathologies or physiological conditions of a person, taking the medication is contraindicated in:
- Hypersensitivity, as well as individual intolerance to the active ingredient or some auxiliary substances of this drug.
- Severe impairment of liver function.
- Severe renal failure.
- Up to 12 years.
- Concomitant drug therapy with Ergotanin and Dihydroergotanin.
With caution, the drug "Azithromycin" should be used for moderate or severe liver or renal failure, as well as various pathologies of cardiac conditions, which are accompanied by a prolongation of the QT interval.
While taking such medications as Warfarin, Digoxin, as well as antiarrhythmic drugs, it is necessary to monitor the patient’s blood condition.
Side effects
Against the background of treatment with the drug “Azithromycin” with a different frequency, some negative reactions may occur.
- Nausea, periodic bouts of vomiting, abdominal pain, accompanied by flatulence. In some cases, the development of constipation, ulcers of the oral mucosa, an increase in the functional activity of the salivary gland is possible.
- Heart palpitations, periodic sensation of heat of the face, less often - a decrease in blood pressure.
- Dizziness, cephalalgia, the appearance of a feeling of fear, insomnia or drowsiness. In some cases, convulsions and severe mental disorders (hallucinations) are possible.
- Inflammatory processes in the liver tissue (hepatitis), increased production of digestive enzymes, which indicates damage to liver cells.
- Rhinitis.
- Shortness of breath and nosebleeds.
- Anemia is a decrease in the number of lymphocytes in the blood.
- Visual and hearing impairment.
- Dry skin, dermatitis, excessive sweating.
- Discomfort during urination.
- Arthralgia, arthritis.
Analogues of the antibiotic "Azithromycin" can also cause side effects.
special instructions
Before using the product, you need to carefully read the annotation, which is contained in the package with tablets. In cases of skipping the medication, the dose should be taken as soon as possible. Against the background of treatment, diarrhea may occur due to a violation of the microflora in the intestine.
The drug "Azithromycin" may interact with other medicines, however, it is necessary to warn the specialist who prescribes this drug.
"Azithromycin" affects the functional state of the central nervous system. Exceeding the dosage of tablets leads to increased signs of negative reactions. The first symptoms are vomiting and hearing loss. Treatment is carried out by a specialist and includes gastric lavage, the appointment of intestinal sorbents, as well as symptomatic therapy.
Analogues of Azithromycin
Similar in composition and effect of the drug "Azithromycin" are:
- "Azimycin".
- "Azicide."
- "Azitroks".
- Azimed.
- "Erythromycin."
- "Zitrolide Forte."
"Erythromycin" also refers to the group of macrolides, available in the form of tablets, ointments for the eyes and for local external use. Blocks protein synthesis. With prolonged use, it inhibits harmful microorganisms. Effective for dysentery, trachoma, scarlet fever, whooping cough, childhood pneumonia and inflammation of the eye mucosa, infectious lesions of the gallbladder, chlamydia, gonorrhea. "Zitrolide Forte" - is available in capsules, the main substance in the composition of azithromycin. It treats otitis media, tonsillitis, sinusitis, bronchitis caused by bacteria, pneumonia, infectious skin lesions, erysipelas, infections of the genitourinary system.
We also give imported analogues of "Azithromycin":
- "Azitral" (India) - is used for lesions of soft tissues and skin, respiratory tract, genital infections.
- Sumamed (Croatia) - effective for diseases of ENT organs, infections of the respiratory system, soft tissues, skin, as well as genital pathologies.
- “Hemomycin” (Serbia) is an analogue of “Azithromycin”, which treats pathologies of the digestive system, respiratory organs, as well as skin lesions
- "Ketek" (Italy) - prescribed for bronchitis, pharyngitis, acute sinusitis, uncomplicated pneumonia.
Is it possible to purchase analogues of Azithromycin without prescription? Yes, these products do not require a prescription from a doctor.
Reviews
The drug "Azithromycin" has proven itself very well, and there are a lot of positive reviews about it. Patients who used this medication note that after its use, overall health improves significantly, the temperature decreases in acute inflammatory diseases of various origins, and side effects are minimal.
Patients who were prescribed the medication “Azithromycin” for the treatment of infectious pathologies of the respiratory system, observed a significant decrease in the manifestations of unpleasant symptoms in the form of cough, sputum discharge from the bronchi, as well as symptoms of a runny nose and inflammation of the nasopharynx.
In the treatment of skin diseases, patients observed an improvement in their health several days after the initial administration of the tablets, and noted that skin pathologies in the form of purulent wounds, boils and other lesions began to heal intensively even without external exposure to these areas with antimicrobial drugs.
Negative comments
Negative reviews suggest that this drug in tablets causes allergic reactions in the form of skin itching and urticaria, and also provokes some unpleasant effects on the part of the digestive system in the form of dyspepsia, thinning stools, constipation and flatulence.
In addition, the drug is not approved for use in the early stages of bearing a child, which also negatively affects the number of negative reviews. Also, patients are dissatisfied with the occurrence of side effects after using the medicine in children - parents commented on the opinion that the drug reduces immunity and provokes the frequent occurrence of respiratory diseases in their children.
We reviewed the instructions for use with "Azithromycin", reviews and analogues.