Any mental disorder requires complex therapy. And often in the treatment regimen include the drug Tizercin. Reviews of experts indicate that the tool really helps to cope with psychomotor agitation that develops against a background of various diseases (including schizophrenia and oligophrenia).
Of course, people who are faced with the need to take medicine are looking for additional information. What are the properties of Tizercin? Instructions for use, reviews, prices, analogues - these are important data that should be studied before the start of therapy.
Features of the composition. Product release form
Unfortunately, today many people are faced with the need to take the drug Tizercin. Instructions for use, price, reviews - these are important facts. But first, it’s worth studying the general characteristics of the product.
Tizercin is available in the form of small, round, film-coated tablets. The main active ingredient is levomepromazine (1 tablet - 25 mg of the substance). In addition, the composition contains magnesium stearate, lactose, potato starch, povidone. For the manufacture of the shell, titanium dioxide, magnesium stearate, hypromellose, dimethicone are used.
In addition, the drug is made in the form of a solution for injection. This is a clear liquid, packaged in 1 ml glass ampoules. One serving (ampoule) contains 25 mg of levomepromazine. As for excipients, anhydrous citric acid, sodium chloride, monothioglycerol, as well as purified water as a solvent are present in the composition.
How does the drug affect the body?
"Tizercin" is a very effective antipsychotic agent of the phenothiazine series. This antipsychotic blocks the dopamine D2 receptors of the mesocortical and mesolimbic system, thereby exerting an antipsychotic effect.
The drug has sedative properties - it calms the nervous system, relieves anxiety and irritability, copes with anxiety and other symptoms. By the way, the medicine also acts as a sleeping pill.
Tizercin tablets also have antiemetic and hypothermic properties. They relieve pain by acting as analgesics. In addition, during therapy, a decrease in blood pressure is observed.
The drug is quickly absorbed by the walls of the digestive tract. The maximum concentration of levomepromazine in the blood is observed approximately 1 to 3 hours after administration. The substance is rapidly distributed throughout tissues and organs. Metabolism occurs in the liver - as a result of chemical reactions, glucuronide and sulfate conjugates are formed, which are excreted by the kidneys.
The drug "Tizercin": indications for use
Reviews indicate that this is a very effective antipsychotic. So in what cases do doctors recommend taking this medicine?
The drug helps to relieve psychomotor agitation in diseases such as schizophrenia, epilepsy, oligophrenia. Tablets are effective in all kinds of bipolar disorders and psychoses (including intoxication and senile).
In what other cases is it advisable to take Tizercin tablets? Reviews of experts say that the drug copes with anxiety, panic attacks, persistent forms of insomnia, various phobias, agitation. As part of complex therapy, tablets are used for shingles, facial neuritis, trigeminal neuralgia - they help relieve pain and alleviate the patient's condition.
Instruction Approximate dosage
For various psychomotor disorders, the drug Tizercin is often used. Reviews indicate that the medicine is really effective. But the dosage in this case is selected individually in each case.
The initial dose is 25 - 50 mg - it must be divided into several doses, and the maximum amount should be taken before bedtime. The dose is increased daily by 25 - 50 mg, bringing it to 200 - 300 mg per day. As soon as the patient's condition is stabilized, the daily amount of the drug begins to slowly decrease. Of course, during the whole time it is necessary to monitor the patient's condition, adjusting the dose depending on the appearance or disappearance of certain symptoms.
As a rule, therapy begins with intramuscular injection of a solution. Such treatment is carried out in a hospital, as the patient's condition (in particular, indicators of his blood pressure) must be constantly monitored. After improvements appear, the patient is transferred to outpatient treatment and pills are prescribed.
Contraindications: who should not take the medicine?
Despite the fact that the drug is considered relatively safe, not everyone can take it. There are contraindications, and their list needs to be studied.
- The medicine is not prescribed for patients with hypersensitivity to some of its constituent components, as well as phenothiazines.
- Contraindications include chronic heart failure, liver and kidney failure.
- The drug is not used for Parkinson's disease, multiple sclerosis.
- Contraindications include angle-closure glaucoma, severe forms of arterial hypertension, porphyria.
- Do not prescribe “Tizercin” to children (reviews indicate that in this case it is very difficult to choose an effective and safe dose).
- The medicine is not recommended to be taken during pregnancy. If there is a need for therapy during lactation, breastfeeding should be discontinued.
Adverse Reactions Information
What are the dangers associated with taking the drug Tizercin? Reviews of doctors, as well as the results of statistical surveys, confirm that adverse reactions rarely develop during treatment. But still, you need to familiarize yourself with their list.
- Most often, therapy provokes a violation of the cardiovascular system. Against the background of taking pills, a decrease in blood pressure often occurs until the development of orthostatic hypotension. Tachycardia is sometimes observed.
- The drug can affect hematopoiesis, causing eosinophilia, pancytopenia, leukopenia, agranulocytosis.
- The medicine affects the central nervous system. Against the background of therapy, the development of a malignant antipsychotic syndrome is sometimes observed. Sometimes intracranial pressure rises. Some patients complain of slurred speech and confusion. Epileptic seizures are possible.
- Therapy sometimes negatively affects the metabolic processes and causes fluctuations in the hormonal background. Sudden weight loss is possible. Sometimes there is the development of galactorrhea. Women sometimes complain of menstrual irregularities.
- Adverse reactions from the excretory system are possible. Their list includes urinary retention, as well as its discoloration.
- Sometimes there are violations of the digestive tract. Some patients complain of nausea, constipation, unpleasant, sometimes painful sensations in the abdomen, as well as dry mouth.
- If we are talking about long-term therapy, then the development of pigmented retinopathy is possible.
- Do not exclude the likelihood of developing allergic reactions. Therapy is sometimes associated with skin rash, itching, burning, the appearance of urticaria.
How to replace the medicine?
What should a patient do who, for one reason or another, cannot take the Tizercin antipsychotic (EGIS)? The pharmacological market offers a fairly large selection of such drugs. For example, with various mental disorders, Haloperidol is widely used. Sulpiride and Droperidol are also effective analogues of this drug.
Of course, self-medication with the help of antipsychotics is unacceptable. These are serious medications that affect the central nervous system. Their inept use can only further complicate the situation.
How much is the drug?
In modern medical practice, the drug Tizercin is often used. Instructions for use, reviews, indications and contraindications are information that must be studied. But for many patients, one of the important factors is cost.
Of course, it’s almost impossible to name the exact number, because much here depends on the pricing policy of the pharmacy. On average, the cost of one package, consisting of 50 tablets, ranges from 210 to 280 rubles.
Tizercin medicine: reviews of patients and doctors
This drug is often used in medical practice. Experts say that the medicine really helps to stop various symptoms of psychomotor disorders. In a correctly selected dose, the tablets help to cope with anxiety, nervousness, insomnia and other problems. The drug rarely causes any complications (despite an impressive list of adverse reactions), and there are not so many contraindications.
It must be understood that diseases such as schizophrenia, bipolar disorder, oligophrenia require complex treatment. These pills help relieve some symptoms, but do not cope with the disease itself.