"Janine" birth control pills belong to modern low-dose hormonal drugs. They have a pronounced therapeutic effect. They help to cope with pain during menstruation, to defeat endometriosis. Normalize the menstrual cycle and protect against unwanted pregnancy. They should be used only as directed by a doctor.
The composition and form of the drug
"Janine" birth control pills contain two active ingredients, these are ethinyl estradiol in an amount of 0.03 mg and dienogest in a dosage of 2 mg. Data are per capsule.
Additional components in the composition of the tablets are lactose monohydrate, talc, potato starch, gelatin, magnesium stearate. The pill shell consists of dextrose, sucrose, povidone K25, macrogol 35000, calcium carbonate, carnauba wax and titanium dioxide.
The tablets produce white and rounded shapes. Packaged in blisters for 21 pieces. In a cardboard box there is one or three aluminum blisters. For the convenience of taking each tablet, the day of the week is written, this helps the woman not to stray and carefully monitor the intake of pills.
Pharmacological features
Birth control pills "Janine" have a pronounced contraceptive effect, which is manifested only when exposed to various complementary mechanisms. First of all, this is a warning of ovulation, as well as a change in the viscosity state of cervical mucus, because of which it becomes simply impermeable to sperm.
If you use the medicine in accordance with the instructions, then the Pearl index, which reflects the number of pregnant women after taking the capsules, does not reach one. With contraceptive use and pill misses, the Pearl Index goes up steadily.
Dienogest in the composition of "Janine" is characterized by antiandrogenic activity. Positive effect on the lipid profile of the blood.
Women who use a combined contraceptive inside notice a normal menstrual cycle. On critical days, they are almost not worried about pain, the volume of secretions is reduced, the duration of menstruation is reduced. This reduces the likelihood of ladies with iron deficiency anemia, ovarian cancer and endometrium.
Dienogest is completely absorbed into the intestinal wall. The maximum concentration of the active substance in the blood is observed 2.5 hours after taking the pill. The bioavailability of the drug is 96%, and its half-life from plasma ranges from 8.5 to 10.8 hours. A small part of the drug is excreted unchanged, along with urine, and the bulk comes in the form of metabolites through the kidneys in a ratio of 3: 1.
Ethinyl estradiol, like dienogest, has complete and rapid absorption. The maximum plasma concentration is observed after 1.5-4 hours. At the first intake, it is metabolized in the liver, which affects the bioavailability of the component, which is 44%. Ethinyl estradiol is completely distributed (98%), combining with albumin. It undergoes a presystemic biotransformation in the liver and small intestine. It is processed by aromatic hydroxylation. Unchanged, it is not excreted from the human body. Metabolites go out with bile and urine.
Indications for use
"Janine" birth control pills are used to protect against unwanted pregnancy. These are the main indications for the use of the drug.
Contraindications
The drug is not used for hypersensitivity to the active substances of the drug and its additional components. It is not recommended to take pills for arterial and venous thrombosis, thromboembolism. A ban on the use of "Janine" are conditions preceding the formation of thrombosis. You can not drink pills for migraines, accompanied by focal neurological phenomena.
A ban on the use of dragees is diabetes mellitus, in which vascular complications are observed, as well as the likelihood of venous or arterial thrombosis. These are diseases that have arisen due to trauma to the heart valve, pathology of the brain vessels of the brain, atrial fibrillation, and diseases of the coronary heart arteries.
Do not prescribe a medication for arterial hypertension and serious surgery. Do not take the drug to smokers over the age of 35 years.
It is forbidden to take pills for people with pancreatitis, liver failure and with severe liver ailments.
You should not use a contraceptive in the presence of tumors, hormone-dependent malignant pathologies, and also if there is the slightest suspicion of their presence in the body. You can not use the drug for vaginal bleeding of unknown origin. A contraindication to the reception is pregnancy and breastfeeding.
Method of application, dosage
The drug "Janine" is taken orally. Tablets should be drunk at the same time in the order that is drawn on the blister.
The medicine is taken one pill a day for twenty-one days, then take a break with a week-long duration. It is at this time that menstruation should come. Then they start taking pills from a new package. Menstruation comes on 2-3 days after using the last capsule from the old package. They may not end by the period when you need to take a capsule from a new blister.
Use of the drug begins if other contraceptives were not used in the previous month, as well as on the first day of menstruation. The medicine can be used on 2-5 days of monthly bleeding, but at the same time, secondary measures will be required to protect against unnecessary pregnancy during the next week, when pills from a new package will be taken.
When switching to "Janine" from other combined contraceptives, you need to use the capsule on the next day after using the last pill or inactive capsule from the blister of the drug taken earlier. The interval between the use of dragees from the new and old packaging should not exceed a week. If a woman switches to a contraceptive with a transdermal patch or vaginal ring, then use should begin on the day of removal of these elements. A lady is transferred from progestational contraceptives (“mini-pills”) to “Janine” on any day without taking a break. The transition from an implant or contraceptive with gestagen, administered intrauterine, is performed on the day of their removal. The transition from injection should be done at the moment when the next injection is expected. In all these cases, you need to use additional contraception throughout the first week of using "Janine."
This tool is used after an abortion, which took place in the first trimester of pregnancy. In this case, the lady can take the drug immediately after the specified procedure. Zhanin is allowed to drink on the 21–28th day after the birth of the child and after an abortion carried out in the II trimester. If you take pills later, you should take additional methods of protection for seven days of taking pills.
If a woman had already had sex before taking dragees, then before using Zhanina, a possible pregnancy should be excluded or menstruation should be expected.
Skip pills
If the lady missed the birth control pill "Janine", and the delay did not exceed twelve hours, then the protective effect of this remedy does not decrease. You need to take a pill as soon as possible. Subsequent pills are consumed as usual.
If one birth control pill “Janine” is lost, what should I do? If the delay in taking the drug is more than twelve hours, then contraceptive protection is reduced. The following concepts should be relied on here:
- The break in taking dragees should not exceed seven days.
- To achieve effective blocking of the hypothalamic-pituitary-ovarian regulation, you need to take the medicine continuously for seven days.
If you are late in taking this remedy for more than 12-36 hours, you need to take pills at the earliest opportunity, even if you have to drink two capsules at the same time. In the future, the drug is taken in the usual rhythm. During the week, additional contraception should be used.
If sexual intercourse was before the lady missed taking the medicine, then the process of fertilization of the egg is possible.
If the capsule is missed in the second week of using a hormonal contraceptive, then you need to take a pill as soon as possible. The next dragee is taken at the usual time. If a woman did not take a break in taking pills during the previous week, then there is no need to use auxiliary contraceptive measures. Otherwise, the situation is when two or more capsules are missed, here you should resort to additional protective measures throughout the week of taking the hormonal agent.
Is it possible to get pregnant by taking birth control pills "Janine"? No, if you do not skip taking the pills. Skipping dragees, especially in the third week, increases the risk of pregnancy due to the proximity of a break in drug use. If there was no break in the previous seven days of taking the drug, then secondary protection measures should not be used. If during the indicated period omissions of taking pills took place, then:
- The lady should drink the pill as soon as possible, even if you have to take two at once. The following capsules should be drunk at the usual time, until all the tablets in the blister pack have run out. Reception of a dragee from a new package should be started immediately, without a week break. While taking the drug, spotting or bleeding of a breakthrough nature can be observed.
- A lady can stop taking pills from the current package and take a week break, including a day with a missed tablet, and then start taking capsules, but from a new blister.
Pregnancy after taking birth control pills "Janine" may occur if the pill was missed, and during the weekly break, menstruation did not come.
Special reception situations
If, when taking active pills, a lady experienced vomiting or diarrhea within four hours, then the absorption of the drug will be incomplete. In this case, take secondary protective measures and drink birth control pills "Janine" in the same way as with a missed dragee.
To postpone the day the menstruation begins, you should not take a week break, but you need to continue to drink pills from the new blister until the day that the woman wants to. The second package can be used by a lady completely without a seven-day break. When taking pills from the second blister, breakthrough bleeding, as well as minor spotting, may disturb. Resume medication after a week-long break.
If there are no periods when taking birth control pills "Janine", then this indicates an excessive suppression of the hormonal work of the ovaries. In this case, you should consult a doctor for a comprehensive diagnosis and establish the cause of this phenomenon.
Side effects
“Janine” birth control pills should be used only as prescribed by the gynecologist. Instructions for use fully describe all the nuances of taking this tool. Often, when using the drug, women are faced with negative phenomena, such as nausea, vomiting reflex. In the genital area, changes in vaginal secretion can occur, breast tenderness and engorgement may occur, disturb secretion from the breasts, lack of sexual desire.
Also, pills can cause bad mood, headache, migraine, and depression. During the use of the drug, chloasma, fluid retention in the body were noticed, contact lens intolerance and allergy were recorded.
Analogs
They have not only a contraceptive effect, but also treat birth control pills "Janine". Instructions are attached to them and should be studied before using the drug. If for some reason this remedy did not fit, then it can be replaced with the following pills, these are:
- "Yarina."
- "Jess."
- Marvelon
- Triquilar.
- Loveston.
- Benatex.
- Chloe.
- "Microlute".
You should not replace the hormonal drug yourself, because only a doctor, having assessed the state of women's health, will be able to choose the right analogue correctly.
Cost
"Janine" birth control pills (the instructions describe in detail contraindications that should be considered before using this contraceptive) are sold in a package containing twenty-one tablets and in a box containing three blisters (63 capsules). The first option costs around 800 rubles, the second - 2000 rubles.
Birth control pills "Janine": reviews
This drug has a variety of reviews. Positive opinions about the pills say that they are 100% protective against unwanted pregnancy, treat endometriosis, polycystic ovaries and glandular hyperplasia. They help normalize the menstrual cycle, remove the symptoms of PMS. Women note that after their intake they do not gain weight, but, on the contrary, lose weight. Some have noticeably improved hair and skin condition. These ladies were satisfied with the drug and continue to take birth control pills "Janine."
Negative reviews indicate that this remedy can cause side effects, including headache, vomiting, nausea, pain in the liver, decreased libido, mood swings, addiction and withdrawal, painful breasts and prolonged bleeding. Many patients say that Janine birth control pills are quite expensive.
Reviews of doctors about the drug are mostly positive. They often recommend it for endometriosis, a cyst, to normalize the menstrual cycle, as well as for painful and heavy periods. They consider it a good low-dose hormone that can completely protect against unwanted pregnancy.