Sometimes patients are prescribed Dibazole medication. What is the cure for? "Dibazole" is a synthetic drug with an active substance called bendazole, which is characterized by a vasodilating, hypotensive and antispasmodic effect. It well reduces blood pressure, helps restore peripheral nerves, and also stimulates spinal cord function. The drug "Dibazole" has an immunostimulating effect, increasing the body's resistance to the effects of certain infectious pathogens.
Pharmacology
The relaxation of the smooth muscles of blood vessels or internal organs occurs due to a decrease in the content of free calcium in them. The drug "Dibazole" causes an improvement in synaptic transmission in the spinal cord, an increase in the synthesis of nucleic acids and proteins. Due to the formation of antibodies when taking the medication, the synthesis of interferon and phagocytosis, it activates the patient's immune system. Under the influence of bendazole, interneuronal contacts in the spinal cord are improved.
Indications
Intravenous or intramuscular injections, tablets with different dosages for adults and children allow the use of the drug "Dibazol" in both inpatient and outpatient settings. Why does this medication help? He successfully copes with the removal of hypertensive crises, with the treatment of arterial hypertension at an early stage in combination with other antihypertensive drugs.
With a peptic ulcer of the digestive tract, intestinal, renal, and
hepatic colic, the drug helps relieve spasms of the smooth muscles of these organs. Has a medicine
"Dibazol" indications for use in neurology. So, it is used to eliminate the residual effects of poliomyelitis, for the treatment of peripheral
paralysis of the facial nerve, polyneuritis and other ailments. The drug "Dibazole" is also prescribed by doctors as a prophylactic against influenza.
Adult Injection Dosage
Injections of the drug "Dibazol" are widespread and often used in a hospital. The drug is produced in the form of a 0.5% or 1% solution for parenteral administration of 1, 2 or 5 ml in each ampoule. The dosage should be determined by the attending physician, who knows all the subtleties of the course of the disease in a particular patient, as well as the characteristics of his body. In hypertensive crisis, intravenous administration (more effective than intramuscular) of the drug is usually prescribed. Dose - 3-4 ml (with 1% solution) or 6-8 ml (with 0.5% solution).
But with hypertension without symptoms of crisis, as a rule, 2-4 ml (with a 1% solution) or 4-8 ml (with a 0.5% solution) are prescribed. But if there are other diseases, the dosage can be increased or decreased by decision of the doctor.
The drug "Dibazole" in tablets
The medication in the form of tablets is available for children at 2, 3, 4 mg and for adults at 20 mg. The package contains 10 pieces. The drug "Dibazole" (tablets), the instruction recommends that an adult patient take 2-3 times a day - the dosage is from 20 to 40 mg of the drug at each dose. For the best effect, the medication is consumed 2 hours before a meal or 2 hours after it.
With lesions of the nervous system, the average dosage of the drug (5 mg) is shown from 5 to 10 times a day. Maximum doses for adult patients: at one time - 0.05 g, per day - 0.15 g of the drug. The course of treatment with any form of medication should last about 3-4 weeks. If necessary, it can be repeated, but not earlier than in one to two months.
The drug "Dibazol" (tablets) has a quick and thin outer shell. This allows the active substance bendazole to begin to act quickly. This form of medication is easy to use, which makes it convenient for use in outpatient treatment. It is remarkably absorbed in the intestine, the effect of the application can be observed after half an hour. The effect of the drug lasts for two to three hours.
Use in childhood
The drug is prescribed for children in the treatment of diseases of the nervous system, ulcers and colic, as well as prevention in the flu season. The question of the need for the use of the drug is decided only by the doctor, assessing the course of the disease, the individual characteristics of the body of a particular child, and also making sure that there are no contraindications.
For outpatient or inpatient treatment, tablets with a child dosage or intravenous / intramuscular injection are used. The form of the drug is also prescribed only by a specialist. During the course of treatment, the doctor monitors the condition of the child, although side effects of the medication are not common. The instruction authorizes the use of the drug "Dibazol" for children and determines such a dosage in accordance with age:
- older than 12 years - 5 mg / day;
- from nine to twelve - no more than 4 mg / day;
- from four to eight - not more than 3 mg / day;
- from a year to three - no more than 2 mg / day;
- up to a year - no more than 1 mg / day.
The doses in the instructions are advisory in nature, therefore, under no circumstances should they be used for self-medication. If further use of the drug is necessary, subsequent courses of therapy are prescribed after 1-2 months.
Pregnant and Nursing Use
Often in obstetrics and gynecology, the drug "Dibazol" is prescribed. What is it prescribed for, is its use safe? These issues are very worrying for women. The drug "Dibazol" is widely used to treat pregnant and lactating mothers. It effectively lowers blood pressure.
For more than 60 years of its successful use in medicine, no adverse effects on the fetus or newborn have been noticed. But still, you need to know that the drug should not be used for self-medication without a doctor’s prescription. It is not suitable for daily use and is considered an emergency aid for pregnant and lactating women.
Contraindications
Having found out everything about the drug "Dibazol" (from which it is prescribed and in what doses it is necessary to take), it is also necessary to find out about all contraindications. The medication can not be used with increased individual sensitivity to its components. The drug "Dibazole" is not recommended for use in case of arterial hypotension and with severe renal impairment. It can not be used to relieve spasms of the digestive tract, if peptic ulcer is accompanied by bleeding. The drug is prohibited for the appointment of patients in whom diabetes, severe heart failure, convulsive syndrome or diseases accompanied by a decrease in muscle tone. Taking the drug, it is necessary to carefully control transport or complex mechanisms.
Side effects
Most often, the drug "Dibazol" is well tolerated, but in some cases there are allergic reactions to its components. When used in high doses, excessive sweating, a feeling of heat, nausea, dizziness, and headache may occur. Caution should be exercised when prescribing long-term treatment courses to elderly people, since a medication can cause deterioration in the results of an electrocardiogram.
Antispasmodic drugs
Pain, which is caused by involuntary contractile activity of the smooth muscles of blood vessels and organs, is called spasms.
To ease them, antispasmodics have been created, which are divided into groups depending on the area of influence (vessels, gastrointestinal tract, bronchi). In the last century, in the 40s, one of these drugs, Dibazol, was synthesized. "Papaverine", "Papazol", "No-shpa", "Tanacekhol", "Avisan", "Baralgin" - all these are antispasmodic drugs that have a similar effect (analogues).
The synonyms include drugs with the following names: "Bendazol", "Dibazol-UBF", "Dibazol-Darnitsa", "Dibazol-Vial".