"Ceraxon" is a synthetic nootropic. It has a wide range of effects. The drug reduces the severity of neurological symptoms, inhibits the phospholipase effect and regenerates the membrane part of the cells. In the instructions for use of "Ceraxon" (in sachets), the main indications for admission are: hemorrhagic and ischemic strokes, brain and head injuries, as well as cognitive and behavioral disorders.
Release form
The drug is on sale in the following forms:
- a solution for oral administration (inside, by mouth) of a pinkish color;
- solution for injection (intramuscular, intravenous and intravenous drip) is colorless;
- pills of a whitish color, oval.
Also in pharmacies you can see the drug, packaged in a sachet. This is a bag of bulk medicine, from which the suspension is prepared.
The composition of the drug
One injection vial contains 1000 mg or 500 mg of the main substance, citicoline. As auxiliary components, water for injection, sodium hydroxide or hydrochloric acid are used. Pack the solution in ampoules of 4 ml, which are placed in the cells of the contour packaging. After everything is sealed in cardboard boxes.
A 100 ml oral solution contains 10 g of citicoline and additional excipients.
The solution is poured into a glass container of 30 ml.
Tablets contain 500 mg of citicoline and excipients.
These include:
- magnesium stearate and hydrogenated castor oil;
- colloidal silicon dioxide (anhydrous) and croscarmellose sodium;
- talc.
Tablets go on sale in blisters placed in cardboard boxes.
The composition of Ceraxon sachets and tablets is identical.
Pharmacology
Due to the main substance, the drug has a nootropic effect and has a large spectrum:
- enhances the transmission of cholinergic type in the brain of the head;
- regenerates membrane sections of cells;
- inhibits the phospholipase effect;
- stops the formation of active oxygen molecules without a paired electrode (free radical);
- reduces the number of damaged cells in the brain of the head during a stroke (acute);
- inhibits and stops neurological symptoms in case of craniocerebral injuries, and also shortens the duration of post-traumatic coma.
The use of "Ceraxon" in sachets, according to reviews from medical experts, is particularly effective in the treatment of neurological disorders (motor or sensory) that are of vascular or degenerative origin.
The drug during oxygen starvation (hypoxia) of chronic brain tissue produces good results in the treatment of cognitive impairments (lack of initiative, memory impairment, difficulties in performing self-care actions). The instructions for use of Ceraxon in a 1000 mg sachet say that taking the drug slows down the manifestations of amnesia and increases alertness.
This product is well absorbed. Metabolism occurs in the liver and intestines, followed by the formation of cytidine and choline. After entering the body, the active substance enters the brain and integrates into the cell membranes of the cytoplasmic and mitochondrial type. Excretion occurs in a small volume (approximately 15%), 3% with urine and 12% with exhaled air.
Indications for use
Doctors highlight the main testimony for "Ceraxon" in the sachet.
These include:
- stroke (hemorrhagic or ischemic) during the recovery period;
- stroke (ischemic) in the acute period;
- head and brain injuries (during recovery and in the acute period).
Also, the use of "Ceraxon" is necessary for disorders of the intellectual and behavioral type that arose with degenerative and vascular disorders in the brain of the head.
Contraindications
This drug is prohibited for children under 18 years of age and patients with hypersensitivity to the components of the drug. Also, reception is prohibited with pronounced vagotonia.
However, in certain cases (the threat of cerebral palsy, prematurity, congenital pathologies, developmental delay), the doctor may prescribe the use of this drug for children. Before that, he makes a prediction and, if the benefit exceeds the risk, “Ceraxon” is prescribed. Treatment in this case takes place under the close supervision of a doctor. The dosage is individual for each child, taking into account diseases.
Instructions for use "Ceraxon" in sachets and other forms
The drug in the form of a sachet is used 20 minutes before meals or after. To prepare the suspension, it is necessary to open 1 sachet, having previously separated it from the rest. Then the contents are dissolved in 50 ml of water and drunk. The dosage of Ceraxon in a sachet should not exceed 2-3 sachets of medicine in 24 hours. The exact dosage for treatment is determined by the doctor depending on the patient's problem.
The drug in the form of a solution for oral administration can be taken both with food and after. It is pre-diluted in a small amount of water without gas (maximum 100 ml can be used). Take 1 g twice a day. The duration of treatment is determined by a neurologist (usually it lasts no more than 10 days).
When using a solution for oral administration, it is necessary to observe the sequence (for using a special syringe).
- It is necessary to immerse the syringe vertically in the bottle with the drug.
- Pulling the piston up, you must draw the required amount of fluid.
- It can be dissolved in a small amount of warm water without gas or consumed undiluted.
- After administration, the syringe must be thoroughly rinsed and dried. After that, it can be assembled for future use.
According to the instructions, tablets can be taken, regardless of meals. The maximum dosage is 4 tablets. The number of receptions is individual for each patient.
The injection solution is used in several ways. It can be administered intravenously, intramuscularly and intravenously. All manipulations are carried out by a nurse in a medical institution.
Side effects
In rare cases, side effects occur when the drug is taken correctly.
These include:
- mental disorders that manifest as hallucinations;
- from the nervous system, headaches and dizziness are possible;
- dyspnea, from the respiratory system;
- decrease or increase in blood pressure;
- nausea and vomiting, less often diarrhea;
- allergic reactions (urticaria, itching, burning, peeling of the skin) are possible, less often, Quincke's edema and anaphylactic type shock state can occur.
In rare cases, a side effect can manifest itself as a general deterioration in well-being with chills and swelling of the limbs.
Interaction
The main component of the drug (citicoline) is able to increase the effectiveness of levodopa. Therefore, doctors do not recommend the simultaneous use of “Ceraxon” with drugs, which include meclofenoxate.
Overdose
The instructions for the use of "Ceraxon" in sachets and other forms do not indicate data on the consequences of excessive use of the drug. In 98% of cases, the drug is tolerated normally.
Pregnancy and lactation
Currently, the instructions for use of "Ceraxon" in sachets do not contain data on the effect of the drug on the fetus and the baby during breastfeeding. The doctor may prescribe medication for the woman after assessing the risks to the child. If the risk of harm is higher than the benefit, then the woman will have to interrupt breastfeeding.
Analogs and cost
Currently, there are several analogues of Ceraxon in a 1000 mg sachet.
These include:
- "Tanakan", "Kogitum", "Nooklerin", "Nootropil" - solutions for oral administration;
- "Ginkoum", "Neuromet", "Fezam", "Vinpotropil", "Noben" - capsules;
- "Omaron", "Vincentin", "Ginos", "Acefen", "Memotropil" - tablets;
- "Escotropil", "Cerebrolysin", "Cerebrolysate" - solutions for injecting the drug into the body;
- "Cortexin" is an extract of the dry type.
Substitutes are similar in composition to the drug "Ceraxon". Before buying an analogue, it is necessary to coordinate a replacement with your doctor.
The price of "Ceraxon" in a sachet varies from 1 270 to 1 490 rubles.
Terms and conditions of storage
The instructions for use of Ceraxon in a 1000 mg sachet and 1000 and 500 mg tablets indicate that the drug should be stored at a temperature not exceeding 30 degrees Celsius.
The oral solution is not allowed to be frozen and exposed to low temperatures (cool). This can provoke opalescence, but at a temperature above 20 degrees this phenomenon disappears.
special instructions
In a solution for oral administration, small crystals in small quantities can form. This is due to preservatives that can trigger the crystallization process. With proper storage, they dissolve over time, and their appearance does not affect the quality of the drug.
When taking Ceraxon, it is necessary to avoid actions associated with a high concentration of attention (driving, working with dangerous mechanisms). This is due to a decrease in the reaction rate when using the drug. After the course of treatment, everything is normal.
Doctors in the reviews of the drug "Ceraxon" note the following positive qualities.
- It is effective in the treatment of chronic and acute forms of circulatory disorders in the brain of the head.
- It has a regenerative function of cell membranes, and because of this it reduces damage to brain tissue.
- An effective and affordable drug, it can be purchased at every pharmacy.
- The tool is well tolerated, and side effects rarely occur.
- The drug “Ceraxon” has many forms, this facilitates therapy.
- It is used for many neurological diseases.
- The drug has a large evidence base (it is well studied).
Many doctors do not see in “Ceraxon” poor qualities, with the exception of high cost.