The drug "Antisten" (tablets) is a very common remedy for disorders in the cardiovascular system. As a rule, a medicine is part of complex therapy. According to experts, the tool "Antisten" is an excellent supportive, supportive drug.
The active component of the drug is trimetazidine. Describing the action of the drug "Antisten", the instructions for use draws attention to the properties of the active substance. In particular, trimetazidine is able to directly affect cardiomyocytes and brain neurons, optimizing their function and metabolism. The cytoprotective effect of the drug is associated with an increase in energy potential. In this case, oxidative decarboxylation (cleavage of carboxylic acid molecules ) is activated and oxygen consumption is rationalized.
The active component is able to maintain myocardial contractility by preventing a decrease in the intracellular concentration of ATP (adenosine triphosphoric acid) and phosphocreatinin. Trimetazidine normalizes the activity of membrane ion channels, preventing the accumulation of sodium and calcium ions in cardiomyocytes, and stabilizes the content of potassium ions inside the cell.
The active substance prevents the damaging effect of free radicals, ensures the integrity of cell membranes, prevents the activation of neutrophils in ischemic zones, increases the duration of the electric potential.
The Antisten drug reduces the incidence of angina attacks and reduces the need for nitrates. Two weeks after the start of treatment, an increase in exercise tolerance, a decrease in sharp fluctuations in blood pressure are noted. There is also a decrease in tinnitus, dizziness of an ischemic nature. In the presence of vascular eye disease, the Antisten preparation helps to restore the functional activity of the retina.
The drug is prescribed for coronary heart disease, as part of complex therapy to prevent the development of angina attacks. The "Antisten" medication recommends the use in case of cochleovestibular disorders of an ischemic nature: hearing loss, tinnitus, dizziness. Chorioretinal vascular lesions are also referred to as indications.
The drug "Antisten" does not recommend the use of the drug for renal failure, severe disorders of the liver, hypersensitivity to the drug, under the age of eighteen years.
During animal studies, there was no teratogenic effect on the fetus or reproductive function. However, there are no clinical data on the safety of using the Antisten medication in pregnant women. In this regard, the drug is contraindicated during gestation.
The ability of the active component to be excreted in breast milk has not been clarified. When prescribing a medicine to a nursing woman, it is necessary to warn her about the need to stop feeding.
The drug "Antisten" instructions for use recommends taking with food. The duration of therapy is determined by the doctor. Dosage for adults - a tablet twice a day.
Taking the medicine may cause some negative reactions. The most common side effects of the Antisten preparation include vomiting, abdominal pain, diarrhea, nausea and other dyspeptic symptoms. In some cases, orthostatic hypotension, dizziness, tremor, and other extrapyramidal disorders, usually occurring after cessation of therapy, may occur. Allergic reactions in the form of a rash, itching, or urticaria are also likely.
In the course of the studies, no significant effect of the drug on the ability to drive transport, concentrate attention, or exhibit a psychomotor reaction was revealed.
Before using the Antisten medication, you should consult a doctor and study the annotation.