The medicine “Exoderil” is used to treat mycoses, fungal infections of the skin, pityriasis, candidiasis, and inflammatory dermatomycosis. The main form of release is a solution that is placed in dark glass bottles with a screw cap - a dropper made of polyethylene.
The drug "Exoderil." Instructions for use: composition, pharmacokinetics
The main active substance of the drug is naphthyne hydrochloride. Auxiliary components include ethanol, propylene glycol.
The drug has high absorbability when applied to the skin, nails. It does not enter the systemic circulation.
Pharmacodynamics of the drug "Exoderil"
The medicine is intended exclusively for external use. It has a pronounced antifungal effect. The active substance acts on trichophytes, epidermophytes, microsporums, yeast by blocking the enzyme squalene epoxidase, which is necessary for the growth of the microorganism. Suppression of this active substance allows squalene to accumulate in foreign cells, which directly damages them.
In addition to antifungal activity, the drug has an antibacterial effect, which applies to gram-negative, gram-positive microorganisms that accompany mycobacteria (Proteus, Pseudomonas aeruginosa, Staphylococcus aureus). In the clinic, it was proved that the drug has an anti-inflammatory effect, contributes to the disappearance of a symptom such as itching.
The drug "Exoderil." Instructions for use: dosage
The drug is recommended to be applied to affected areas of the skin, nails twice a day. For more comfortable use, there is a special dropper on the cap. Before using the drug, it is necessary to clean the skin, nails with wet swabs, then drain. To improve its absorption, it is necessary to remove part of the hyperkeratotic layers before application. At the end of the procedure, an occlusive dressing with urea is applied. Four days later, the affected part of the nail is removed. To exclude relapse of the disease, a similar procedure is carried out after the disappearance of clinical signs within two weeks.
The drug "Exoderil." Instructions for use: side effects, contraindications
Among the side effects, the appearance of signs of local inflammation, which is manifested by dry skin, burning, redness, is distinguished. All of them are reversible, do not require discontinuation of the drug.
The main contraindication to the use of the drug is hypersensitivity to its components. In addition, it is not recommended to apply the solution to open wounds.
The drug "Exoderil." Instructions for use: special instructions
This medicine is for topical use. It is forbidden to use the drug in ophthalmology, to apply to open wounds. In these cases, it is recommended to use another form of the drug - a cream that does not include ethanol. The drug "Exoderil", the use of which is practically not accompanied by the appearance of adverse reactions, can be used during lactation, as well as during pregnancy.
The drug must be stored in a dark place, protected from children, at a temperature of up to 30 degrees. Shelf life is five years. After this period, the use of the drug is prohibited due to the high probability of toxic effects. The drug is dispensed from pharmacies without a prescription.