This article describes drugs that are similar in name, but based on different active substances and accordingly have different mechanisms of action. The first drug is “Libexin”, the instructions to which are attached, contains preoxidiazine as the active substance. This drug reduces the sensitivity of peripheral receptors (cough). In this case, the peripheral, afferent link of the cough reflex is blocked. The drug "Libexin" also has a central effect on the cough reflex.
If you came to the pharmacy and asked for the Libexin medication, then they can give you the Libexin Muco remedy, the instructions for which are also given here. When closely related, the latter has cardinal differences from the peripheral antitussive drug "Libexin" both in composition and in the mechanism of action. Below are descriptions and instructions for the use of the above drugs.
"Libexin": instruction
The active substance of libexin is prenoxdiazine (prenoxdiazine). The instruction explains the mechanism of action of the Libexin agent by blocking the peripheral parts of the cough reflex. The following effects appear here:
- local anesthetic effect - the sensitivity of peripheral (cough) receptors decreases;
- bronchodilating effect - stretching receptors involved in the cough reflex are suppressed;
- a slight decrease in the activity of the center of respiration (without its inhibition).
Indications for the use of the drug "Libexin"
The instruction prescribes a drug for unproductive cough of any etiology:
- Qatar airways,
- flu
- acute and chronic bronchitis,
- pneumonia
-emphysema.
Contraindications to the use of the drug "Libexin"
The instruction prohibits the use of the drug with:
- hypersensitivity to it;
- diseases associated with increased bronchial secretion;
-conditions after inhalation anesthesia;
- galactose intolerance;
- Lactase deficiency or malabsorption of glucose-galactose.
It should be used with caution in childhood. During pregnancy and lactation, the use of the drug "Libexin" is justified when the expected benefit to the mother is higher than the expected risk to the fetus or child born.
Side effects
Possible appearance:
- allergic reactions,
- dry mouth or throat,
- temporary numbness and loss of sensitivity of the oral cavity.
In one case out of 10 symptoms are possible in the form of pain in the stomach, constipation, nausea.
Interaction with other medicines
The combination of the drug with mucolytic and expectorant drugs is not recommended , because it makes sputum secretion difficult. There is no information on interaction with other medicines.
Mode of application
The tablet is swallowed without chewing in order to avoid oral anesthesia. Adults are prescribed 1 tablet. (100 mg) 3-4 p. in a day. If necessary, the amount can be doubled. For children, the average dose is prescribed based on age and body weight - 0.25-0.5 tablets. (25-50 mg) 3-4 p. in a day.
"Libexin Muco": instructions
Release form and composition
Red syrup for children with aroma of raspberries and cherries. It is packaged in glass bottles of 125-300 ml. It is a mucolytic product with the active substance "carbocysteine."
Auxiliary ingredients in the composition: sucrose, methyl parahydroxybenzoate, vanillin, crimson dye (Ponceau 4R), raspberry or cherry flavor, sodium hydroxide, purified water.
Farm action
Carbocysteine is a mucolytic and acts on the gel phase of the bronchial secretion. At the same time, disulfide bonds of glycoproteins are broken, so the viscosity decreases and the elasticity of the secretion increases.
It is prescribed for acute and chronic bronchopulmonary diseases, in which viscous, difficult to separate sputum is formed. It is prescribed for inflammatory diseases of the facial cavities. Used in preparing the patient for bronchoscopy and bronchography.
Reception methods
Ingestion.
In 1 scoop of syrup (5 ml) contains 100 mg of carbocysteine. Babies 2-5 years old are given 1 scoop - 2 doses / day. Children over 5 years of age: 1 scoop - 3 times / day.
Therapy should not be continued for more than 8 days without medical advice.
Side effect
In the digestive tract, side effects are sometimes noted in the form of nausea, vomiting, diarrhea, epigastric pain, and gastrointestinal bleeding.
Allergic reactions in the form of itching, urticaria, exanthema, angioedema.
Common symptoms are dizziness, weakness, malaise.
Contraindications
Do not prescribe for:
- gastric ulcer in the acute stage;
- chronic glomerulonephritis (acute phase), cystitis;
- pregnancy;
- children under 2 years old;
- high susceptibility to the drug.
With caution in the anamnestic gastric ulcer.
Reviews: "Libexin Muco" for children
Reviews are mostly positive. The drug well dilutes sputum, so that it separates well and the respiratory organs are released. There are no negative reviews for the medicine.